{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:06:48Z","timestamp":1787497608194,"version":"build-2736575974"},"reference-count":26,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1983,5]]},"abstract":"\n \u2713 Spinal cord blood flow (SCBF) and the effect of end-tidal CO\n 2<\/jats:sub>\n concentration (ETCO\n 2<\/jats:sub>\n ) on SCBF (CO\n 2<\/jats:sub>\n reactivity) were studied in the lumbar spinal cord of cats by means of the hydrogen-clearance technique. Hydrogen gas was administered by inhalation, and its level in spinal cord tissue was estimated amperometrically with small (75 \u00b5m) platinum electrodes. The average SCBF's at normocapnia (ETCO\n 2<\/jats:sub>\n = 4%) of the ventral horn gray matter and of the white matter at several locations were 43.2 and 16.2 ml\u00b7100 gm\n \u22121<\/jats:sup>\n \u00b7min\n \u22121<\/jats:sup>\n , respectively. For gray and white matter, the values of CO\n 2<\/jats:sub>\n reactivity, estimated by the coefficient of the regression of SCBF (ml\u00b7100 gm\n \u22121<\/jats:sup>\n \u00b7min\n \u22121<\/jats:sup>\n ) on ETCO\n 2<\/jats:sub>\n (ml\u00b7100 ml\n \u22121<\/jats:sup>\n ) were 11.6 and 2.1, respectively. No differences in SCBF or CO\n 2<\/jats:sub>\n reactivity were observed between intact animals kept under N\n 2<\/jats:sub>\n O-O\n 2<\/jats:sub>\n ventilation and decerebrated animals with no anesthesia.\n <\/jats:p>\n \n After an acute spinal section, ventral horn SCBF and CO\n 2<\/jats:sub>\n reactivity (measured eight segments below the cordotomy) were not altered, in spite of the profound neural depression present (that is, spinal shock). Orthodromic (dorsal root) stimulation of the ventral horn neurons induced an average increase in blood flow of 128% above control values. Antidromic (ventral root) motoneuron activation failed to produce any significant changes in ventral horn blood flow.\n <\/jats:p>","DOI":"10.3171\/jns.1983.58.5.0742","type":"journal-article","created":{"date-parts":[[2009,5,8]],"date-time":"2009-05-08T12:09:47Z","timestamp":1241784587000},"page":"742-748","source":"Crossref","is-referenced-by-count":15,"title":["Control of blood flow in the cat spinal cord"],"prefix":"10.3171","volume":"58","author":[{"given":"Oscar U.","family":"Scremin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilio E.","family":"Decima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Circ Res","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1161\/01.RES.14.2.164","article-title":"Measurement of local blood flow with hydrogen gas.","volume":"14","author":"Auckland","year":"1964"},{"key":"b2","series-title":"J Physiol (Lond)","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1113\/jphysiol.1953.sp005013","article-title":"Intracellular recording from antidromically activated motoneurones.","volume":"122","author":"Brock","year":"1953"},{"key":"b3","series-title":"Blood Flow and Metabolism in the Brain.","first-page":"1.16","article-title":"Effect of acute sections of the brain stem on hypercapnic vasodilatation of cerebral and spinal vessels","author":"Capon","year":"1975"},{"key":"b4","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"801","DOI":"10.3171\/jns.1980.52.6.0801","article-title":"Comparison of hydrogen clearance and 14C-antipyrine autoradiography in the measurement of spinal cord blood flow after severe impact injury.","volume":"52","author":"Cawthon","year":"1980"},{"key":"b5","series-title":"Proc Int Union Physiol Sci","first-page":"373","article-title":"Blood flow and neural activity in the spinal cord of the cat.","volume":"14","author":"Decima","year":"1980"},{"key":"b6","series-title":"Fed Proc","first-page":"599","article-title":"Control of blood flow in the cat spinal cord.","volume":"39","author":"Decima","year":"1980"},{"key":"b7","series-title":"J Physiol (Lond)","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1113\/jphysiol.1951.sp004603","article-title":"Observations on the blood flow in the spinal cord of the rabbit.","volume":"114","author":"Field","year":"1951"},{"key":"b8","series-title":"Acta Neurol Scand Suppl","first-page":"46","article-title":"Regional clearance of hydrogen as a measure of cerebral blood flow.","volume":"14","author":"Fieschi","year":"1965"},{"key":"b9","series-title":"Dtsch Z J Nervenheilkd","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1007\/BF01660125","article-title":"\u00dcber die Vasodilatatoren in den peripheren Nerven und hinteren R\u00fcckenmarkswurzeln beim Menschen.","volume":"107","author":"Foerster","year":"1928"},{"key":"b10","series-title":"Res Publ Assoc Res Nerv Ment Dis","first-page":"316","article-title":"Brain metabolism and circulation.","volume":"18","author":"Gerard","year":"1938"},{"key":"b11","series-title":"J Neurol Neurosurg Psychiatry","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1136\/jnnp.36.1.42","article-title":"Spinal cord blood flow in dogs. 2. The effect of the blood gases.","volume":"36","author":"Griffiths","year":"1973"},{"key":"b12","series-title":"Cerebral Vascular Smooth Muscle and Its Control.","first-page":"339","article-title":"The significance of cortical extracellular H+, K+ and Ca2+ activities for regulation of local cerebral blood flow under conditions of enhanced neuronal activity","author":"Heuser","year":"1978"},{"key":"b13","series-title":"J Physiol (Lond)","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1113\/jphysiol.1952.sp004796","article-title":"The vasodilator activity of spinal roots.","volume":"118","author":"Holton","year":"1952"},{"key":"b14","series-title":"Exp Neurol","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/0014-4886(74)90006-5","article-title":"Regional cerebral blood flow of the main visual pathways during photic stimulation of the retina in intact and split-brain monkeys.","volume":"42","author":"Kato","year":"1974"},{"key":"b15","series-title":"J Clin Invest","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1172\/JCI101995","article-title":"The effect of altered arterial tensions of carbon dioxide and oxygen on cerebral blood flow and cerebral oxygen consumption of normal young men.","volume":"27","author":"Kety","year":"1948"},{"key":"b16","series-title":"Physiol Rev","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1152\/physrev.1978.58.3.656","article-title":"Local chemical and neurogenic regulation of cerebral vascular resistance.","volume":"58","author":"Kuschinsky","year":"1978"},{"key":"b17","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"335","DOI":"10.3171\/jns.1980.52.3.0335","article-title":"Spinal cord blood flow in experimental transient traumatic paraplegia.","volume":"52","author":"Lohse","year":"1980"},{"key":"b18","series-title":"Circ Res","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1161\/01.RES.41.1.128","article-title":"Regulation of total and regional spinal cord blood flow.","volume":"41","author":"Marcus","year":"1977"},{"key":"b19","first-page":"650","article-title":"Use of platinum black cathode for local blood flow measurements in vivo","author":"Misrahy"},{"key":"b20","series-title":"Brain","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1093\/brain\/94.4.635","article-title":"Contralateral focal increase of cerebral blood flow in man during arm work.","volume":"94","author":"Olesen","year":"1971"},{"key":"b21","series-title":"Arch Neurol","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1001\/archneur.1976.00500080001001","article-title":"Correlation between regional cerebral blood flow and oxidative metabolism. 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