{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T13:38:21Z","timestamp":1783777101041,"version":"3.55.0"},"reference-count":19,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1983,6]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 Two cases of sphenoethmoidal encephalocele with cleft palate are reported in detail. The encephaloceles had prolapsed into the nose and nasopharynx, and protruded into the mouth. Previous examples of this entity are reviewed. Such patients have a typical facial appearance: hypertelorism, median cleft lip, and bifid nose of varied severity. Ocular findings include coloboma of the optic nerve or anophthalmia. The prolapsed cerebral tissue varies from nonfunctional glia elements to vital structures of the hypothalamus-pituitary area. Agenesis of the corpus callosum has been reported consistently.<\/jats:p>\n<jats:p content-type=\"fine-print\">Transcranial access to the bone defect, particularly its posterior portion, is difficult because of distorted cerebral anatomy and abnormal vasculature. The fragility of the prolapsed cerebral tissue makes it difficult to preserve the cerebral tissue intact and to reposition it into the cranium. When there is a cleft palate, it is possible to repair the encephalocele extracranially through a transoral, transpalatal approach, preserving and repositioning the content of the sac. Dural closure and obliteration of the bone defects are other essential steps of the operation. Both patients reported here were successfully operated on by the transoral, transpalatal route, at the age of 3 months and 4 years, respectively. They were followed for several years and had comprehensive endocrinological work-ups. One patient exhibited some pituitary deficiency requiring substitution therapy.<\/jats:p>","DOI":"10.3171\/jns.1983.58.6.0924","type":"journal-article","created":{"date-parts":[[2009,5,8]],"date-time":"2009-05-08T18:25:26Z","timestamp":1241807126000},"page":"924-931","source":"Crossref","is-referenced-by-count":28,"title":["Sphenoethmoidal cephalocele with cleft palate: transpalatal versus transcranial repair"],"prefix":"10.3171","volume":"58","author":[{"given":"Michael L.","family":"Lewin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Acta Neurochir","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1007\/BF01401170","article-title":"A case of sphenopharyngeal encephalocele.","volume":"22","author":"Avanzini","year":"1970"},{"key":"b2","series-title":"Neurology","doi-asserted-by":"publisher","first-page":"694","DOI":"10.1212\/WNL.9.10.694","article-title":"Agenesis of the corpus callosum with associated facial anomalies.","volume":"9","author":"Bell","year":"1959"},{"key":"b3","series-title":"Ergebn Chir Orthop","first-page":"258","article-title":"Die Hirnbr\u00fcche und Hirnspalten.","volume":"22","author":"Cordes","year":"1929"},{"key":"b4","series-title":"Clinical Ophthalmology.","first-page":"13","volume":"2","author":"Duane","year":"1980"},{"key":"b5","series-title":"J Clin Endocrinol Metab","doi-asserted-by":"publisher","first-page":"854","DOI":"10.1210\/jcem-51-4-854","article-title":"Hypothalamic-pituitary functions in patients with transsphenoidal encephalocele and midfacial anomalies.","volume":"51","author":"Ellyin","year":"1980"},{"key":"b6","series-title":"Dtsch Z Chir","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1007\/BF02797244","article-title":"\u00dcber basale cephalocelen.","volume":"90","author":"Exner","year":"1907"},{"key":"b7","series-title":"Zentralbl Neurochir","first-page":"85","article-title":"Zur Therapieproblem bei Sphenoethmoidalen Meningozelen.","volume":"40","author":"Gerhardt","year":"1979"},{"key":"b8","series-title":"Ann Chir Plast","first-page":"93","article-title":"[Dermal graft. Procedures for protection of meninges and re-enforcement of dura.]","volume":"12","author":"Guiot","year":"1967"},{"key":"b9","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1056\/NEJM194306242282502","article-title":"Spina bifida and cranium bifidum. IV. An unusual nasopharyngeal encephalocele.","volume":"228","author":"Ingraham","year":"1943"},{"key":"b10","series-title":"Maroc Med","first-page":"73","article-title":"Les meningo-encephaloceles anterieures de la base du crane.","volume":"40","author":"Jacob","year":"1961"},{"key":"b11","series-title":"Neuroradiology","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1007\/BF00345727","article-title":"Transsphenoidal meningocele with hypothalamic insufficiency.","volume":"18","author":"Larsen","year":"1979"},{"key":"b12","series-title":"Radiol Clin Biol","first-page":"386","article-title":"Sphenopharyngeal encephalomeningocele.","volume":"34","author":"Lau","year":"1965"},{"key":"b13","series-title":"Cleft Palate J","first-page":"61","article-title":"Spheno-pharyngeal meningocele and cleft palate. Case report with 12-year follow-up.","volume":"13","author":"Lewin","year":"1976"},{"key":"b14","series-title":"Arch Surg","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1001\/archsurg.1965.01320110023005","article-title":"Transpalatal correction of basilar meningocele with cleft palate.","volume":"90","author":"Lewin","year":"1965"},{"key":"b15","series-title":"Childs Brain","first-page":"140","article-title":"Sphenoethmoidal encephalocele: a case report with review of the literature.","volume":"3","author":"Modesti","year":"1977"},{"key":"b16","series-title":"Br J Surg","first-page":"757","article-title":"An encephalocele associated with hypertelorism and cleft palate.","volume":"25","author":"Oldfield","year":"1937"},{"key":"b17","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1148\/90.3.442","article-title":"Transsphenoidal and transethmoidal encephaloceles: a review of clinical and roentgen features in 8 cases.","volume":"90","author":"Pollock","year":"1968"},{"key":"b18","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"397","DOI":"10.3171\/jns.1979.51.3.0397","article-title":"Sphenoethmoidal meningoencephalocele associated with agenesis of corpus callosum and median cleft lip and palate. Case report.","volume":"51","author":"Sakoda","year":"1979"},{"key":"b19","series-title":"Psychiatr Neurol Neurochir","first-page":"243","article-title":"Nasopharyngeal transsphenoidal encephalocele, craterlike hole in the optic disc and agenesis of the corpus callosum. Pneumoencephalographic visualisation in a case.","volume":"67","author":"Van Nouhuys","year":"1964"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/58\/6\/article-p924.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/58\/6\/article-p924.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/58\/6\/article-p924.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,13]],"date-time":"2022-11-13T05:08:45Z","timestamp":1668316125000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/58\/6\/article-p924.xml"}},"subtitle":["Report of two cases"],"short-title":[],"issued":{"date-parts":[[1983,6]]},"references-count":19,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.3171\/jns.1983.58.6.0924","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[1983,6]]}}}