{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T00:36:21Z","timestamp":1792283781700,"version":"4.4.0"},"reference-count":21,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1984,3]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 Lymph was collected from cervical lymphatic trunks of anesthetized cats under conditions of normal cerebrospinal fluid (CSF) pressure and again when the CSF pressure was elevated by infusing artificial CSF into the subarachnoid space at the cisterna magna. There was an immediate increase in lymph flow on initiation of the CSF infusion, but this increase was not maintained although the CSF infusion continued. Lymph protein concentrations fell when the CSF infusion started and remained depressed while the infusion of CSF continued. It is postulated that under steady-state conditions much of the CSF leaving the subarachnoid space via the cranial nerves enters the capillaries from the extravascular spaces, and that large molecules from the CSF, such as proteins, return to the blood via the lymphatic system.<\/jats:p>","DOI":"10.3171\/jns.1984.60.3.0577","type":"journal-article","created":{"date-parts":[[2009,5,8]],"date-time":"2009-05-08T16:22:49Z","timestamp":1241799769000},"page":"577-581","source":"Crossref","is-referenced-by-count":20,"title":["The effects of raised ICP on lymph flow in the cervical lymphatic trunks in cats"],"prefix":"10.3171","volume":"60","author":[{"given":"James A.","family":"Love","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald A.","family":"Leslie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"J Physiol (Lond)","first-page":"67P","article-title":"Proportion of cerebrospinal fluid draining into jugular lymphatic trunks of the cat.","volume":"276","author":"Bradbury","year":"1978"},{"key":"b2","series-title":"J Physiol (Lond)","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1113\/jphysiol.1980.sp013129","article-title":"The role of the lymphatic system in drainage of cerebrospinal fluid and aqueous humour.","volume":"299","author":"Bradbury","year":"1980"},{"key":"b3","series-title":"Am J Physiol","first-page":"F329","article-title":"Drainage of cerebral interstitial fluid into deep cervical lymph of the rabbit.","volume":"240","author":"Bradbury","year":"1981"},{"key":"b4","series-title":"J Anat","first-page":"153","article-title":"The connexions of the spinal subarachnoid space with the lymphatic system.","volume":"82","author":"Brierley","year":"1948"},{"key":"b5","series-title":"Br J Exp Pathol","first-page":"179","article-title":"The prelymphatic pathways of the brain as revealed by cervical lymphatic obstruction and the passage of particles.","volume":"57","author":"Casley-Smith","year":"1976"},{"key":"b6","series-title":"Aust J Exp Biol Med Sci","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1038\/icb.1951.30","article-title":"The removal of protein from the subarachnoid space.","volume":"29","author":"Courtice","year":"1951"},{"key":"b7","series-title":"Physiology of the Cerebrospinal Fluid.","first-page":"42","author":"Davson","year":"1967"},{"key":"b8","series-title":"Brain","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1093\/brain\/93.4.665","article-title":"The mechanism of drainage of the cerebrospinal fluid.","volume":"93","author":"Davson","year":"1970"},{"key":"b9","series-title":"Arch Otolaryngol","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1001\/archotol.1979.00790160014003","article-title":"Subarachnoid space of the CNS, nasal mucosa, and lymphatic system.","volume":"105","author":"Jackson","year":"1979"},{"key":"b10","series-title":"Neurology","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1212\/WNL.26.7.659","article-title":"The effect of cerebrospinal fluid pressure on the size of drainage pathways.","volume":"26","author":"James","year":"1976"},{"key":"b11","series-title":"Studien der Anatomie des Nervensystems und des Bindegewebes.","author":"Key","year":"1875"},{"key":"b12","series-title":"Acta Neurochir","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1007\/BF01406783","article-title":"Compression of cerebral vessels by intracranial hypertension. 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