{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:58:45Z","timestamp":1760983125214},"reference-count":19,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1984,7]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 The authors present the cases of nine patients with acquired immunodeficiency syndrome (AIDS) and intracerebral mass lesions, who were evaluated at the University of California, San Francisco, between April, 1979, and July, 1983. Eight patients were confirmed homosexual males, and none was Haitian. Their average age was 38.8 years. Tissue diagnosis was made in all patients from brain biopsy or autopsy material. Three patients initially presented for evaluation of their neurological deficits, while the other six already carried the diagnosis of AIDS at admission. Seven patients presented with multiple intracranial lesions and two had polymicrobial infection. In this series, three patients had <jats:italic>Toxoplasma gondii<\/jats:italic> brain abscesses, two had primary lymphoma, two had metastatic Kaposi's sarcoma of the central nervous system (CNS), two had focal cytomegalovirus encephalitis and one each had cryptococcal and <jats:italic>Candida albicans<\/jats:italic> brain abscesses. The clinical presentation, radiological evaluation, and serodiagnostic study of these patients were not helpful in establishing the nature of the CNS lesions. Brain biopsy is considered by the authors to be critical for the evaluation and appropriate treatment of mass lesions in patients with AIDS.<\/jats:p>","DOI":"10.3171\/jns.1984.61.1.0009","type":"journal-article","created":{"date-parts":[[2009,5,8]],"date-time":"2009-05-08T16:12:18Z","timestamp":1241799138000},"page":"9-16","source":"Crossref","is-referenced-by-count":94,"title":["Central nervous system mass lesions in the acquired immunodeficiency syndrome (AIDS)"],"prefix":"10.3171","volume":"61","author":[{"given":"Robert M.","family":"Levy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent G.","family":"Pons","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark L.","family":"Rosenblum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Principles and Practice of Infectious Diseases.","first-page":"2127","article-title":"Toxoplasma gondii","author":"Anderson","year":"1979"},{"key":"b2","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1227\/00006123-198303000-00005","article-title":"Computed tomographic guidance stereotaxis in the management of intracranial mass lesions.","volume":"12","author":"Apuzzo","year":"1983"},{"key":"b3","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1056\/NEJM198201283060432","article-title":"Epidemiologic aspects of the current outbreak of Kaposi's sarcoma and opportunistic infections.","volume":"306","author":"Centers for Disease Control","year":"1982"},{"key":"b4","series-title":"Morbid Mortal Weekly Rep","first-page":"507","article-title":"Update on acquired immune deficiency syndrome (AIDS) \u2014 United States.","volume":"31","year":"1982"},{"key":"b5","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"157","DOI":"10.3171\/jns.1982.57.2.0157","article-title":"Intraoperative use of real-time ultrasonography in neurosurgery.","volume":"57","author":"Chandler","year":"1982"},{"key":"b6","series-title":"Ann Intern Med","doi-asserted-by":"publisher","first-page":"693","DOI":"10.7326\/0003-4819-96-6-693","article-title":"Disseminated Kaposi's sarcoma in homosexual men.","volume":"96","author":"Friedman-Kien","year":"1982"},{"key":"b7","series-title":"JAMA","doi-asserted-by":"publisher","first-page":"2941","DOI":"10.1001\/jama.1982.03330220003001","article-title":"Neurological complications now characterizing many AIDS victims.","volume":"248","author":"Gapen","year":"1982"},{"key":"b8","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"1425","DOI":"10.1056\/NEJM198112103052401","article-title":"Pneumocystis carinii pneumonia and mucosal candidiasis in previously healthy homosexual men. Evidence of a new acquired cellular immunodeficiency.","volume":"305","author":"Gottlieb","year":"1981"},{"key":"b9","series-title":"Ann Neurol","first-page":"80","article-title":"Neurological complications of gay-related immunodeficiency disorder.","volume":"12","author":"Horowitz","year":"1982"},{"key":"b10","series-title":"Lancet","first-page":"598","article-title":"Kaposi's sarcoma in homosexual men \u2014 a report of eight cases.","volume":"2","author":"Hymes","year":"1981"},{"key":"b11","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1056\/NEJM198301133080205","article-title":"Impaired cell-mediated immunity in patients with classic hemophilia.","volume":"308","author":"Lederman","year":"1983"},{"key":"b12","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1056\/NEJM198308113090608","article-title":"Acquired immunodeficiency syndrome and cranial-nerve abnormalities.","volume":"309","author":"Lehrich","year":"1983"},{"key":"b13","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"1431","DOI":"10.1056\/NEJM198112103052402","article-title":"An outbreak of community-acquired Pneumocystis carinii pneumonia. Initial manifestation of cellular immune dysfunction.","volume":"305","author":"Masur","year":"1981"},{"key":"b14","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1056\/NEJM198305053081813","article-title":"Evaluation of cerebral-mass lesions in acquired immunodeficiency syndrome.","volume":"308","author":"Pitchenik","year":"1983"},{"key":"b15","series-title":"AJR","doi-asserted-by":"publisher","first-page":"861","DOI":"10.2214\/ajr.140.5.861","article-title":"Toxoplasma encephalitis in Haitian adults with acquired immunodeficiency syndrome: a clinical-pathologic-CT correlation.","volume":"140","author":"Post","year":"1983"},{"key":"b16","series-title":"Ann Anat Pathol","first-page":"125","article-title":"Complications infectieuses pulmonaires et neurologiques d'un sarcome de Kaposi. Corr\u00e9lation anatomoclinique avec \u00e9tude ultrastructurale.","volume":"25","author":"Rutsaert","year":"1980"},{"key":"b17","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1056\/NEJM198301063080112","article-title":"Primary lymphoma of the nervous system associated with acquired immune-deficiency syndrome.","volume":"308","author":"Snider","year":"1983"},{"key":"b18","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1056\/NEJM198301203080303","article-title":"Acquired immune deficiency in Haitians. Opportunistic infections in previously healthy Haitian immigrants.","volume":"308","author":"Vieira","year":"1983"},{"key":"b19","series-title":"Lancet","first-page":"572","article-title":"Kaposi's sarcoma and Toxoplasma gondii brain abscess in a Spanish homosexual.","volume":"1","author":"Vilaseca","year":"1982"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/61\/1\/article-p9.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/61\/1\/article-p9.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/61\/1\/article-p9.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,24]],"date-time":"2022-07-24T18:41:42Z","timestamp":1658688102000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/61\/1\/article-p9.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,7]]},"references-count":19,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.3171\/jns.1984.61.1.0009","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[1984,7]]}}}