{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T17:10:41Z","timestamp":1764781841071},"reference-count":19,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1987,3]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 The long-term results of praziquantel therapy in 141 patients with neurocysticercosis are presented. Seventy-five patients (53%) were considered to be cured because the cysts or nodules disappeared or became calcified following praziquantel treatment and the patients were asymptomatic at the end of a 5-year follow-up period. An additional 35 patients (24.8%) improved clinically and radiographically. The intraventricular <jats:italic>Cysticercus<\/jats:italic> cysts of five patients in this group were not affected by praziquantel and had to be surgically removed. The remaining 31 patients (21.9%) were unchanged or became worse probably because, prior to therapy, <jats:italic>Cysticercus<\/jats:italic> larvae had caused tissue damage. The fact that praziquantel did not affect intraventricular cysts suggests a low concentration of the drug in the cerebrospinal fluid. Surgery continues to be an important tool in the treatment of cysticercosis to remove parasites that do not respond to praziquantel therapy as well as for the relief of intracranial hypertension.<\/jats:p>","DOI":"10.3171\/jns.1987.66.3.0359","type":"journal-article","created":{"date-parts":[[2009,5,8]],"date-time":"2009-05-08T16:11:54Z","timestamp":1241799114000},"page":"359-363","source":"Crossref","is-referenced-by-count":41,"title":["Long-term results of praziquantel therapy in neurocysticercosis"],"prefix":"10.3171","volume":"66","author":[{"given":"Clemente","family":"Robles","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Maria","family":"Sedano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noe","family":"Vargas-Tentori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonia","family":"Galindo-Virgen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"J Bras Med Edicao Suppl","first-page":"42","article-title":"Tratamiento da cisticercose cut\u00e2nea com praziquantel.","volume":"45","author":"Baranski","year":"1983"},{"key":"b2","series-title":"Am J Trop Med Hyg","doi-asserted-by":"publisher","first-page":"811","DOI":"10.4269\/ajtmh.1982.31.811","article-title":"Treatment of cysticercosis with praziquantel in Colombia.","volume":"31","author":"Botero","year":"1982"},{"key":"b3","series-title":"J Bras Med Edicao Suppl","first-page":"52","article-title":"Resultados con praziquantel en neurocisticercose.","volume":"45","author":"Casta\u00f1o","year":"1983"},{"key":"b4","series-title":"Esp Vet (Mex)","first-page":"159","article-title":"Droncit en el tratamiento de la cisticercosis porcina.","volume":"1","author":"Chavarria","year":"1970"},{"key":"b5","series-title":"N Engl J Med","first-page":"733","article-title":"Praziquantel for cysticercosis of the brain parenchyma.","volume":"311","author":"Ciferri","year":"1984"},{"key":"b6","series-title":"Salud Publica Mex","first-page":"643","article-title":"Resultado de las necropsias de tres pacientes con diagn\u00f3stico de cisticercosis, tratados con praziquantel.","volume":"24","author":"D\u00e1valos Mata","year":"1982"},{"key":"b7","series-title":"Ann Intern Med","doi-asserted-by":"publisher","first-page":"179","DOI":"10.7326\/0003-4819-99-2-179","article-title":"Cerebral cysticercosis treated biphasically with dexamethasone and praziquantel.","volume":"99","author":"deGhetaldi","year":"1983"},{"key":"b8","series-title":"Rev Med Hosp Gral Mex","first-page":"73","article-title":"Evolucion histopatologica de la cisticercosis cutanea tratada con praziquantel.","volume":"47","author":"Galindo","year":"1984"},{"key":"b9","series-title":"Rev Med Hosp Gen Mex","first-page":"128","article-title":"Primer caso de cisticercosis cerebral tratado con prednisolona resultado satisfactorio.","volume":"23","author":"Gamboa Acosta","year":"1959"},{"key":"b10","series-title":"Neurol Colomb","first-page":"503","article-title":"Tratamiento de la neurocisticercosis con praziquantel.","volume":"4","author":"G\u00f3mez","year":"1980"},{"key":"b11","series-title":"Gac Med Mex","first-page":"17","article-title":"Tratamiento de la cisticercosis con praziquantel. 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