{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T10:04:19Z","timestamp":1790849059031,"version":"4.1.0"},"reference-count":15,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1988,6]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 The authors describe five cases of subependymal giant-cell astrocytoma in children in which many clinical, histological, immunohistochemical, and ultrastructural features typical of this tumor were present. However, prominent focal necrosis and mitoses, features usually associated with high-grade tumors, were seen in all cases. Despite the presence of necrosis and mitoses, clinical follow-up studies have revealed a lack of aggressive tumor behavior after surgery alone. The discrepancy between the histological and clinical features in these cases is emphasized so that excessive treatment of a basically low-grade tumor may be avoided. Mast cells were seen in all five cases, often in large numbers.<\/jats:p>","DOI":"10.3171\/jns.1988.68.6.0880","type":"journal-article","created":{"date-parts":[[2009,5,8]],"date-time":"2009-05-08T16:14:12Z","timestamp":1241799252000},"page":"880-883","source":"Crossref","is-referenced-by-count":38,"title":["Subependymal giant-cell astrocytoma in children"],"prefix":"10.3171","volume":"68","author":[{"given":"Chung W.","family":"Chow","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey L.","family":"Klug","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth A.","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","doi-asserted-by":"publisher","DOI":"10.3109\/01913128009141432"},{"key":"b2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00691851"},{"key":"b3","unstructured":"Burger PC, Vogel FS:Surgical Pathology of the Nervous System and Its Coverings.New York: John Wiley & Sons, 1976, pp 235\u2013237"},{"key":"b4","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197608)38:2<729::AID-CNCR2820380216>3.0.CO;2-Z"},{"key":"b5","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-197907000-00007"},{"key":"b6","unstructured":"Enzinger FM, Weiss SW:Soft Tissue Tumors.St Louis: CV Mosby, 1983, pp 381\u2013383"},{"key":"b7","doi-asserted-by":"publisher","DOI":"10.1007\/BF00690396"},{"key":"b8","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1967.26.2.0191"},{"key":"b9","doi-asserted-by":"publisher","DOI":"10.1007\/BF00691876"},{"key":"b10","unstructured":"Rubinstein LJ:Tumors of the Central Nervous System. Atlas of Tumor Pathology, Series 2, Fascicle 6.Washington, DC: Armed Forces Institute of Pathology, 1972, pp 7\u201317"},{"key":"b12","unstructured":"Russell DS, Rubinstein LJ:Pathology of Tumours of the Nervous System, ed 4.London: Edward Arnold, 1977, pp 165\u2013166"},{"key":"b13","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1979.50.2.0240"},{"key":"b14","doi-asserted-by":"publisher","DOI":"10.1007\/BF00688011"},{"key":"b15","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410090211"},{"key":"b16","doi-asserted-by":"publisher","DOI":"10.1007\/BF00690320"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/68\/6\/article-p880.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/68\/6\/article-p880.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/68\/6\/article-p880.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,14]],"date-time":"2022-05-14T05:19:49Z","timestamp":1652505589000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/68\/6\/article-p880.xml"}},"subtitle":["An unusual discrepancy between histological and clinical features"],"short-title":[],"issued":{"date-parts":[[1988,6]]},"references-count":15,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.3171\/jns.1988.68.6.0880","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[1988,6]]}}}