{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T14:26:41Z","timestamp":1791901601010,"version":"4.3.4"},"reference-count":19,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1988,7]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 Percutaneous retrogasserian glycerol instillation was performed under local anesthesia for treatment of trigeminal neuralgia in 162 patients. A simplified technique that did not involve cisternography was used. Initial pain relief was achieved in 146 patients (90.1%). Recurrent pain was noted in 27 patients (18.5%) and was more frequent (50%) in patients who had undergone surgical treatments prior to glycerol injection than in those who had no previous surgical treatment (12.3%). A second glycerol injection was carried out in nine patients and a third injection in two patients. The follow-up period extended from 6 to 67 months and 77.8% of patients are totally pain-free after one or more glycerol injections. Another 8.6% experienced good pain relief with the addition of small doses of pharmacological agents. Thus, 140 (86.4%) of the original 162 patients experienced satisfactory pain control following glycerol rhizolysis.<\/jats:p>\n<jats:p content-type=\"fine-print\">Initial sensory loss on the face occurred in 117 patients (71.6%) but at last follow-up examination only 46 patients (28%) experienced mild orofacial hypalgesia and 13 patients (8%) noted analgesia. The corneal reflex was absent in three patients (1.8%) and reduced in five (3.1%). No patients noted corneal ulceration or anesthesia dolorosa. Percutaneous retrogasserian glycerol rhizolysis offers a rapid, safe, reliable, and relatively inexpensive surgical approach to treatment of trigeminal neuralgia.<\/jats:p>","DOI":"10.3171\/jns.1988.69.1.0039","type":"journal-article","created":{"date-parts":[[2009,5,8]],"date-time":"2009-05-08T16:16:40Z","timestamp":1241799400000},"page":"39-45","source":"Crossref","is-referenced-by-count":111,"title":["Glycerol rhizolysis for treatment of trigeminal neuralgia"],"prefix":"10.3171","volume":"69","author":[{"given":"Ronald F.","family":"Young","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1227\/00006123-197811000-00007","volume":"3","author":"Apfelbaum RI","year":"1978","journal-title":"Neurosurgery"},{"key":"b2","first-page":"152","volume":"66","author":"Arias MJ","year":"1987","journal-title":"J Neurosurg"},{"key":"b3","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1986.65.1.0032"},{"key":"b4","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1227\/00006123-198404000-00007","volume":"14","author":"Bennett MH","year":"1984","journal-title":"Neurosurgery"},{"key":"b5","doi-asserted-by":"crossref","first-page":"2519","DOI":"10.1001\/jama.1981.03310490037024","volume":"245","author":"Dalessio D","year":"1981","journal-title":"JAMA"},{"key":"b6","first-page":"93","volume":"6","author":"Gomori JM","year":"1985","journal-title":"AJNR"},{"key":"b7","first-page":"927","volume-title":"Advances in Pain Research and Therapy","volume":"5","author":"H\u00e5kanson S","year":"1983"},{"key":"b8","first-page":"137","volume":"10","author":"H\u00e5kanson S","year":"1978","journal-title":"Surg Neurol"},{"key":"b9","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-198112000-00005"},{"key":"b10","volume-title":"The effect of pure glycerol on rat sciatic nerve. An experimental model for treatment of trigeminal neuralgia with glycerol injections.","author":"H\u00e5kanson S","year":"1982"},{"key":"b11","first-page":"151","volume":"66","author":"Lunsford LD","year":"1987","journal-title":"J Neurosurg"},{"key":"b12","first-page":"680","volume":"3","author":"Lunsford LD","year":"1982","journal-title":"AJNR"},{"key":"b13","doi-asserted-by":"publisher","DOI":"10.1001\/jama.248.4.449"},{"key":"b14","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-198404000-00006"},{"key":"b15","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1001\/archneur.1985.04060020060016","volume":"42","author":"Lunsford LD","year":"1985","journal-title":"Arch Neurol"},{"key":"b16","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1227\/00006123-198312000-00012","volume":"13","author":"Rengachary SS","year":"1983","journal-title":"Neurosurgery"},{"key":"b17","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198607173150307"},{"key":"b18","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1227\/00006123-198112000-00006","volume":"9","author":"Sweet WH","year":"1981","journal-title":"Neurosurgery"},{"key":"b19","first-page":"167","volume":"15","author":"Whisler WW","year":"1972","journal-title":"Neurochirurgia (Stuttg)"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/69\/1\/article-p39.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/69\/1\/article-p39.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/69\/1\/article-p39.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,14]],"date-time":"2022-05-14T06:14:17Z","timestamp":1652508857000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/69\/1\/article-p39.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,7]]},"references-count":19,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.3171\/jns.1988.69.1.0039","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[1988,7]]}}}