{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T16:19:25Z","timestamp":1758817165344},"reference-count":28,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1991,11]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 The present study evaluates the interdependence of clinical stage, cerebral vasospasm, intracranial pressure (ICP), and transcranial Doppler ultrasonographic parameters. The mean flow velocity of blood in the middle cerebral artery and the index of cerebral circulatory resistance as a measure of the peripheral vascular flow resistance were determined in 76 patients with spontaneous subarachnoid hemorrhage. The ICP was measured using an epidural transducer in 41 patients. There was no case in which both high ICP and a high mean flow velocity were observed simultaneously. The investigations led to the following conclusions. 1) In patients with a resistance index of less than 0.5, changes in the mean flow velocity seem to reflect sufficiently the actual severity and time course of vasospasm. 2) During the time course of vasospasm, an increase in the resistance index above values of 0.6 with a simultaneously decreased mean flow velocity indicates a rise in ICP rather than a reduction in vasospasm. 3) With a pronounced increase in ICP, evaluation of the severity and time course of vasospasm by transcranial Doppler ultrasonography based solely upon the mean flow velocity can lead to false-negative results.<\/jats:p>","DOI":"10.3171\/jns.1991.75.5.0752","type":"journal-article","created":{"date-parts":[[2009,5,19]],"date-time":"2009-05-19T16:23:20Z","timestamp":1242750200000},"page":"752-758","source":"Crossref","is-referenced-by-count":69,"title":["Cerebral vasospasm evaluated by transcranial Doppler ultrasonography at different intracranial pressures"],"prefix":"10.3171","volume":"75","author":[{"given":"J\u00fcrgen","family":"Klingelh\u00f6fer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirk","family":"Sander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manfred","family":"Holzgraefe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Bischoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bastian","family":"Conrad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Neuroradiology","first-page":"11","article-title":"A transcranial Doppler method in the evaluation of cerebrovascular spasm.","volume":"28","author":"Aaslid","year":"1986"},{"key":"b2","series-title":"J Neurosurg","first-page":"769","article-title":"Noninvasive transcranial Doppler ultrasound recording of flow velocity in basal cerebral arteries.","volume":"57","author":"Aaslid","year":"1982"},{"key":"b3","series-title":"Stroke","first-page":"1300","article-title":"Management of aneurysmal subarachnoid hemorrhage.","volume":"19","author":"Biller","year":"1988"},{"key":"b4","series-title":"Stroke","first-page":"1466","article-title":"Transcranial Doppler measurements of the middle cerebral artery. Effect of hematocrit.","volume":"19","author":"Brass","year":"1988"},{"key":"b5","series-title":"The Pathophysiology of Increased Intracranial Pressure. Current Concepts.","year":"1978"},{"key":"b6","series-title":"J Neurol Neurosurg Psychiatry","first-page":"1499","article-title":"Cerebral blood velocity in subarachnoid haemorrhage. 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II: Relation of complication rates to clinical and arteriographic diagnosis.","volume":"131","author":"Mani","year":"1978"},{"key":"b19","series-title":"J Neurosurg","first-page":"98","article-title":"Report of the Cooperative Study of Intracranial Aneurysms and Subarachnoid Hemorrhage. Cerebral angiography. An analysis of the diagnostic value and complications of carotid and vertebral angiography in 5,484 patients.","volume":"25","author":"Perret","year":"1966"},{"key":"b20","series-title":"Present and Future of Diagnostic Ultrasound.","first-page":"141","article-title":"Diagnostic ultrasound for cerebral vascular diseases","author":"Pourcelot","year":"1976"},{"key":"b21","series-title":"Stroke","first-page":"963","article-title":"Noninvasive assessment of CO2-induced cerebral vasomotor response in normal individuals and patients with internal carotid artery occlusion.","volume":"19","author":"Ringelstein","year":"1988"},{"key":"b22","series-title":"J Neurosurg","first-page":"25","article-title":"Relationship between hemispheric cerebral blood flow, central conduction time, and clinical grade in aneurysmal subarachnoid hemorrhage.","volume":"62","author":"Rosenstein","year":"1985"},{"key":"b23","series-title":"J Neurosurg","first-page":"594","article-title":"Cerebral vasospasm evaluated by transcranial ultrasound correlated with clinical grade and CT-visualized subarachnoid hemorrhage.","volume":"64","author":"Seiler","year":"1986"},{"key":"b24","series-title":"Neurosurgery","first-page":"813","article-title":"Value of transcranial Doppler examination in the diagnosis of cerebral vasospasm after subarachnoid hemorrhage.","volume":"22","author":"Sekhar","year":"1988"},{"key":"b25","series-title":"J Neurosurg","first-page":"186","article-title":"Intracranial pressure changes following aneurysm rupture. Part I: Clinical and angiographic correlations.","volume":"56","author":"Voldby","year":"1982"},{"key":"b26","series-title":"J Neurosurg","first-page":"48","article-title":"Regional CBF, intraventricular pressure, and cerebral metabolism in patients with ruptured intracranial aneurysms.","volume":"62","author":"Voldby","year":"1985"},{"key":"b27","series-title":"Stroke","first-page":"905","article-title":"Transcranial Doppler in cerebrovascular disease.","volume":"17","author":"Wechsler","year":"1986"},{"key":"b28","series-title":"J Neurosurg","first-page":"173","article-title":"Time course of vasospasm in man.","volume":"48","author":"Weir","year":"1978"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/75\/5\/article-p752.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/75\/5\/article-p752.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/75\/5\/article-p752.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,19]],"date-time":"2023-03-19T22:33:30Z","timestamp":1679265210000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/75\/5\/article-p752.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,11]]},"references-count":28,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.3171\/jns.1991.75.5.0752","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[1991,11]]}}}