{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T15:54:32Z","timestamp":1773762872671,"version":"3.50.1"},"reference-count":12,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1992,10]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 Between January, 1981, and July, 1991, 17 infants under 1 month of age were admitted to The Hospital for Sick Children with the signs and symptoms of a Chiari II malformation. These patients' presentation included swallowing difficulty (71%), stridor (59%), apneic spells (29%), aspiration (12%), weakness of cry (18%), and arm weakness (53%). Decompression of the Chiari II malformation was performed in all patients, with a time interval between onset of symptoms and surgery ranging from 1 to 121 days. Fifteen patients (88%) remain alive, all of whom have shown a complete recovery. The mean follow-up period in this group of patients was 65 months. Two patients died, one due to respiratory arrest 8 months after decompression and the other because of shunt infection and peritonitis 7 years after decompression. These results support the concept that compressive forces, rather than a primary intrinsic disorder of the brain-stem nuclei, play a crucial etiological role in the development of a symptomatic Chiari II malformation. Early recognition of the symptoms of Chiari II malformation should be followed by immediate decompressive laminectomy in order to promote a prompt and full neurological recovery.<\/jats:p>","DOI":"10.3171\/jns.1992.77.4.0541","type":"journal-article","created":{"date-parts":[[2009,5,27]],"date-time":"2009-05-27T01:43:38Z","timestamp":1243388618000},"page":"541-544","source":"Crossref","is-referenced-by-count":73,"title":["Surgical decompression for symptomatic Chiari II malformation in neonates with myelomeningocele"],"prefix":"10.3171","volume":"77","author":[{"given":"William P.","family":"Vandertop","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akio","family":"Asai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harold J.","family":"Hoffman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James M.","family":"Drake","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robin P.","family":"Humphreys","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James T.","family":"Rutka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurence E.","family":"Becker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1987.66.6.0812"},{"key":"b2","first-page":"140","volume-title":"Syringomyelia: Current Concepts in Diagnosis and Treatment.","author":"Carmel PW","year":"1991"},{"key":"b3","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(87)80455-9"},{"key":"b4","first-page":"293","volume":"10","author":"Curnes JT","year":"1989","journal-title":"AJNR"},{"key":"b5","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1007\/BF00571117","volume":"5","author":"de la Cruz R","year":"1989","journal-title":"Childs Nerv Syst"},{"key":"b6","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1989.71.2.0159"},{"key":"b7","first-page":"719","volume":"47","author":"Lazareff JA","year":"1990","journal-title":"Bol Med Hosp Infant Mex"},{"key":"b8","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-198308000-00007"},{"key":"b9","first-page":"3","volume-title":"Syringomyelia: Current Concepts in Diagnosis and Treatment.","author":"Sarnat HB","year":"1991"},{"key":"b10","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1212\/WNL.21.7.673","volume":"21","author":"Sieben RL","year":"1971","journal-title":"Neurology"},{"key":"b11","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1986.64.3.0363"},{"key":"b12","first-page":"1075","volume":"9","author":"Wolpert SM","year":"1988","journal-title":"AJNR"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/77\/4\/article-p541.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/77\/4\/article-p541.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/77\/4\/article-p541.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,14]],"date-time":"2022-05-14T04:36:32Z","timestamp":1652502992000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/77\/4\/article-p541.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,10]]},"references-count":12,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.3171\/jns.1992.77.4.0541","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[1992,10]]}}}