{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T12:56:00Z","timestamp":1772110560017,"version":"3.50.1"},"reference-count":25,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1993,3]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 It is commonly believed that differentiating solitary small cysticercus granulomas and small tuberculomas in patients with seizures is difficult without resorting to an excision biopsy. The aim of this study was to formulate clinical and computerized tomography (CT) criteria to distinguish these two entities in patients with epilepsy. Toward this end, clinical and CT data from six consecutive patients with histologically proven small solitary tuberculomas and 25 consecutive patients with histologically proven solitary cysticercus granulomas were compared. Evidence of raised intracranial tension and a progressive focal neurological deficit was seen only in patients with tuberculomas (two of six cases). All tuberculomas were greater than 20 mm in size and five of the six were irregular in outline. Only tuberculomas were associated with a midline shift on CT (four of six cases). All cysticercus granulomas were less than 20 mm in size and 24 (96%) of the 25 were regular in outline, conforming to one of two characteristic patterns. No cysticercus granuloma was associated with a midline shift. Based on the above clinical findings (evidence of raised intracranial tension and a progressive neurological deficit) and CT criteria (size, shape, and association with a midline shift), it is possible to separate these two entities in a majority of patients with seizures and with a single small lesion on CT.<\/jats:p>","DOI":"10.3171\/jns.1993.78.3.0402","type":"journal-article","created":{"date-parts":[[2009,5,27]],"date-time":"2009-05-27T15:30:56Z","timestamp":1243438256000},"page":"402-407","source":"Crossref","is-referenced-by-count":92,"title":["Differentiating solitary small cysticercus granulomas and tuberculomas in patients with epilepsy"],"prefix":"10.3171","volume":"78","author":[{"given":"Vedantam","family":"Rajshekhar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. P.","family":"Haran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. Shankar","family":"Prakash","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathew J.","family":"Chandy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"J Neurol Neurosurg Psychiatry","first-page":"915","article-title":"Disappearing CT lesions in epilepsy: is tuberculosis or cysticercosis the cause?","volume":"52","author":"Ahuja","year":"1989"},{"key":"b2","series-title":"J Neurol Neurosurg Psychiatry","first-page":"1185","article-title":"Appearing and disappearing CT scan abnormalities in India \u2014 an enigma.","volume":"52","author":"Bansal","year":"1989"},{"key":"b3","series-title":"Acta Neurochir","first-page":"27","article-title":"Micro-abscesses and presumptive inflammatory nodules of the brain.","volume":"68","author":"Basauri","year":"1983"},{"key":"b4","series-title":"Br J Radiol","first-page":"935","article-title":"Intracranial tuberculomas: a CT study.","volume":"53","author":"Bhargava","year":"1980"},{"key":"b5","series-title":"Neurol India","first-page":"139","article-title":"Solitary \u201cmicrolesions\u201d in CT: a clinical study and follow-up.","volume":"36","author":"Bhatia","year":"1988"},{"key":"b6","series-title":"J Med Assoc Thai","first-page":"673","article-title":"CT diagnosis of cerebral cysticercosis.","volume":"72","author":"Bhoopat","year":"1989"},{"key":"b7","series-title":"J Neurol Neurosurg Psychiatry","first-page":"702","article-title":"Single small enhancing CT lesions in Indian patients with epilepsy: clinical, radiological and pathological considerations.","volume":"54","author":"Chandy","year":"1991"},{"key":"b8","series-title":"Lancet","first-page":"390","article-title":"Cysticercosis causing single, small CT lesions in Indian patients with seizures.","volume":"1","author":"Chandy","year":"1989"},{"key":"b9","series-title":"Neurology","first-page":"563","article-title":"Neurocysticercosis.","volume":"40","author":"Desai","year":"1990"},{"key":"b10","series-title":"Pediatr Neurosci","first-page":"161","article-title":"Intracranial tuberculomas. 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Review of 127 cases.","volume":"39","author":"McCormick","year":"1982"},{"key":"b15","series-title":"Med J Aust","first-page":"42","article-title":"Childhood central nervous system cysticercosis in Australia.","volume":"149","author":"McKelvie","year":"1988"},{"key":"b16","series-title":"J Comput Assist Tomogr","first-page":"708","article-title":"Cysticercosis mimicking brain neoplasm: MR and CT appearance.","volume":"14","author":"Michael","year":"1989"},{"key":"b17","series-title":"J Neurol Neurosurg Psychiatry","first-page":"936","article-title":"Computed tomography in neurocysticercosis.","volume":"46","author":"Minguetti","year":"1983"},{"key":"b18","series-title":"Pediatrics","first-page":"76","article-title":"Intraparenchymal cerebral cysticercosis in children: diagnosis and treatment.","volume":"82","author":"Mitchell","year":"1988"},{"key":"b19","series-title":"Acta Neurol Scand","first-page":"465","article-title":"Etiology and management of single, small CT lesions in patients with seizures: understanding a controversy.","volume":"84","author":"Rajshekhar","year":"1991"},{"key":"b20","series-title":"J Neurol Neurosurg Psychiatry","first-page":"561","article-title":"Cysticercus immunoblot assay in Indian patients with single small enhancing CT lesions.","volume":"54","author":"Rajshekhar","year":"1991"},{"key":"b21","series-title":"Neurology","first-page":"739","article-title":"Early CT reevaluation after empiric praziquantel therapy in neurocysticercosis.","volume":"39","author":"Rawlings","year":"1989"},{"key":"b22","series-title":"J Neurol Neurosurg Psychiatry","first-page":"866","article-title":"Appearing and disappearing CT scan abnormalities and seizures.","volume":"48","author":"Sethi","year":"1985"},{"key":"b23","series-title":"Handbook of Clinical Neurology.","first-page":"195","article-title":"Tuberculous meningitis","volume":"52","author":"Tandon","year":"1988"},{"key":"b24","series-title":"Neuroradiology","first-page":"329","article-title":"CT of intracranial tuberculomas with specific reference to the \u201ctarget sign.\u201d","volume":"30","author":"van Dyk","year":"1988"},{"key":"b25","series-title":"J Neurol Neurosurg Psychiatry","first-page":"1298","article-title":"Focal epilepsy in India with special reference to lesions showing ring or disc-like enhancement on contrast computed tomography.","volume":"50","author":"Wadia","year":"1987"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/78\/3\/article-p402.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/78\/3\/article-p402.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/78\/3\/article-p402.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,19]],"date-time":"2023-03-19T21:46:16Z","timestamp":1679262376000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/78\/3\/article-p402.xml"}},"subtitle":["Clinical and computerized tomographic criteria"],"short-title":[],"issued":{"date-parts":[[1993,3]]},"references-count":25,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.3171\/jns.1993.78.3.0402","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[1993,3]]}}}