{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T10:45:44Z","timestamp":1787309144665,"version":"build-2736575974"},"reference-count":29,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1996,12]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 In this paper the authors evaluate the results of linear accelerator (LINAC)\u2014based stereotactic radiosurgery for acoustic schwannomas.<\/jats:p><jats:p content-type=\"fine-print\">Fifty-six patients underwent LINAC-based stereotactic radiosurgery for acoustic schwannomas at the University of Florida between July 1988 and November 1994. Each patient was followed for a minimum of 1 year or until death; no patient was lost to follow up. One or more follow-up magnetic resonance images or computerized tomography scans were obtained in 52 of the 56 patients. Doses ranged between 10 and 22.5 Gy with 69.6% of patients receiving 12.5 to 15 Gy. Thirty-eight patients (68%) were treated with one isocenter and the dose was specified to the 80% isodose line in 71% of patients.<\/jats:p><jats:p content-type=\"fine-print\">Fifty-five patients (98%) achieved local control after treatment. The 5-year actuarial local control rate was 95%. At the time of analysis, 48 patients were alive and free of disease, seven had died of intercurrent disease, and one was alive with disease. Complications developed in 13 patients (23%). The likelihood of complications was related to the dose and treatment volume: 10 to 12.5 Gy to all volumes, three (13%) of 23 patients; 15 to 17.5 Gy to 5.5 cm3 or less, two (9%) of 23 patients; 15 to 17.5 Gy to more than 5.5 cm3, five (71%) of seven patients; and 20 to 22.5 Gy to all volumes, three (100%) of three patients.<\/jats:p><jats:p content-type=\"fine-print\">Linear accelerator\u2014based stereotactic radiosurgery results in a high rate of local control at 5 years. The risk of complications is related to the dose and treatment volume.<\/jats:p>","DOI":"10.3171\/jns.1996.85.6.1013","type":"journal-article","created":{"date-parts":[[2009,6,8]],"date-time":"2009-06-08T20:37:01Z","timestamp":1244493421000},"page":"1013-1019","source":"Crossref","is-referenced-by-count":88,"title":["Preliminary results of linear accelerator radiosurgery for acoustic schwannomas"],"prefix":"10.3171","volume":"85","author":[{"given":"William M.","family":"Mendenhall","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William A.","family":"Friedman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John M.","family":"Buatti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis 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