{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T09:34:40Z","timestamp":1768037680522,"version":"3.49.0"},"reference-count":12,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1997,9]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 Twelve consecutive patients with severe spasticity and hypertonia following acquired brain injury were treated with continuous intrathecal infusion of baclofen via an implanted, programmable infusion pump\u2014catheter system for a minimum of 3 months. In every case intrathecal baclofen therapy resulted in a statistically significant reduction in upper- and lower-extremity tone, spasm frequency, and reflexes, contributing to improved functional abilities. There were no untoward side effects or complications associated with treatment.<\/jats:p><jats:p content-type=\"fine-print\">This preliminary assessment indicates that intrathecal administration of baclofen is effective in treating the disabling spasticity caused by acquired brain injury in selected patients.<\/jats:p>","DOI":"10.3171\/jns.1997.87.3.0415","type":"journal-article","created":{"date-parts":[[2009,6,10]],"date-time":"2009-06-10T18:18:10Z","timestamp":1244657890000},"page":"415-419","source":"Crossref","is-referenced-by-count":80,"title":["Prospective assessment of continuous intrathecal infusion of baclofen for spasticity caused by acquired brain injury: a preliminary report"],"prefix":"10.3171","volume":"87","author":[{"given":"Jay M.","family":"Meythaler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"McCary","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark N.","family":"Hadley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1136\/jnnp.37.12.1352","volume":"37","author":"Ashby P","year":"1974","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"b2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1993.78.2.0226"},{"key":"b3","first-page":"129","volume":"5","author":"Goldstein LB","year":"1991","journal-title":"J Neurol Rehabil"},{"key":"b4","volume-title":"Guidelines for the Management of Severe Head Injury.","author":"Joint Section on Trauma and Critical Care of the American Association of Neurological Surgeons and the Brain Trauma Foundation","year":"1995"},{"key":"b5","first-page":"73","volume-title":"Parenteral Drug Therapy in Spasticity and Parkinson's Disease.","author":"Kroin JS","year":"1991"},{"key":"b6","first-page":"51","volume":"5","author":"Mayer NH","year":"1991","journal-title":"J Neurol Rehabil"},{"key":"b7","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9993(96)90034-9"},{"key":"b8","doi-asserted-by":"publisher","DOI":"10.1097\/00002060-199212000-00003"},{"key":"b9","first-page":"794","volume":"73","author":"Meythaler JM","year":"1992","journal-title":"Arch Phys Med Rehabil"},{"key":"b10","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1097\/00003086-198706000-00013","volume":"219","author":"Yarkony GM","year":"1987","journal-title":"Clin Orthop"},{"key":"b11","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1056\/NEJM198105143042010","volume":"304","author":"Young RR","year":"1981","journal-title":"N Engl J Med"},{"key":"b12","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1056\/NEJM198105143042010","volume":"304","author":"Young RR","year":"1981","journal-title":"N Engl J Med"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/87\/3\/article-p415.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/87\/3\/article-p415.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/87\/3\/article-p415.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T14:23:40Z","timestamp":1710426220000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/87\/3\/article-p415.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,9]]},"references-count":12,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.3171\/jns.1997.87.3.0415","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[1997,9]]}}}