{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T02:01:22Z","timestamp":1774922482114,"version":"3.50.1"},"reference-count":44,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1999,5]]},"abstract":"<jats:p content-type=\"fine-print\"><jats:italic>Object.<\/jats:italic> The authors retrospectively analyzed the results of their 6-year experience in the treatment of basilar artery (BA) bifurcation aneurysms by using Guglielmi detachable coils (GDCs).<\/jats:p><jats:p content-type=\"fine-print\"><jats:italic>Methods.<\/jats:italic> This analysis involved 45 BA tip aneurysms in 16 men and 29 women who ranged in age from 23 to 78 years (mean 50 years). Seventy-five percent of the aneurysms had ruptured and 25% remained unruptured. Of the group whose aneurysms hemorrhaged, 14 patients were Hunt and Hess Grade I or II and 20 were Hunt and Hess Grades III to V; 32 patients were treated within 2 weeks of their subarachnoid hemorrhage (SAH). Initially, treatment with GDCs was limited to poor-grade high-risk patients who refused surgery or patients in whom surgery proved unsuccessful. Later in the study, good-grade patients with narrow-necked aneurysms were also treated using GDCs.<\/jats:p><jats:p content-type=\"fine-print\">The length of clinical follow up ranged from 1 to 72 months (average 27.4 months) in the 37 surviving patients. In 33 of the 45 aneurysms treated with coil placement, good to excellent results were achieved. There were 12 poor results (27%) including one in a patient from the non-SAH group who suffered a thrombotic complication due to an underlying vasculitis. Eight deaths were recorded in this group of 45 patients. One of these deaths was caused by a complication related to anesthesia, one by unknown causes, and six resulted from complications of the disease. One patient rebled on the 2nd day after the endovascular procedure. The mortality and permanent morbidity rates directly related to the intervention were 2.2% and 4.4%, respectively.<\/jats:p><jats:p content-type=\"fine-print\">Angiographic studies obtained immediately postintervention demonstrated 99 to 100% occlusion in 30 (67%) of the aneurysms; nine (20%) were more than 90% occluded; and six (13%) were less than 90% occluded by the GDCs. Follow-up angiograms were obtained in 31 patients between 2 and 72 months after coil placement. Nineteen (61%) of the follow-up angiograms revealed stable results (that is, no change from initial treatment). Twelve of the 31 showed coil compaction, but only eight of these lesions could accept additional coils.<\/jats:p><jats:p content-type=\"fine-print\">In large aneurysms recanalization was seen in 57%, and some of the larger lesions required as many as four embolizations (mean 1.7) to achieve optimal occlusion. When small-necked aneurysms were analyzed as a subset, a stable angiographic result was seen in 92%.<\/jats:p><jats:p content-type=\"fine-print\"><jats:italic>Conclusions.<\/jats:italic> Use of GDCs led to excellent clinical and angiographic results in the majority of patients with BA tip aneurysms included in this limited follow-up study. Rebleeding was encountered in one of the 34 previously ruptured BA aneurysms treated with GDCs, and no hemorrhages have been documented in the 11 unruptured aneurysms treated with GDCs in this series. Long-term follow-up studies are necessary before it is possible to compare adequately the treatment of aneurysms with coil placement to the gold standard of aneurysm clipping.<\/jats:p>","DOI":"10.3171\/jns.1999.90.5.0843","type":"journal-article","created":{"date-parts":[[2009,5,13]],"date-time":"2009-05-13T17:21:50Z","timestamp":1242235310000},"page":"843-852","source":"Crossref","is-referenced-by-count":109,"title":["Treatment of basilar artery bifurcation aneurysms by using Guglielmi detachable coils: a 6-year experience"],"prefix":"10.3171","volume":"90","author":[{"given":"Gerhard","family":"Bavinzski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"Killer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Gruber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Reinprecht","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cordell E.","family":"Gross","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernd","family":"Richling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1227\/00006123-198912000-00009","article-title":"Causes of morbidity and mortality from surgery of aneurysms of the distal basilar artery.","volume":"25","author":"Batjer","year":"1989"},{"key":"b2","series-title":"Acta Neurochir","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1007\/BF01417687","article-title":"Endosaccular occlusion of basilar artery bifurcation aneurysms using electrically detachable coils.","volume":"134","author":"Bavinzski","year":"1995"},{"key":"b3","series-title":"Zentralbl Neurochir Suppl","first-page":"4","article-title":"Die differenzierte chirurgische Behandlung von Aneurysmen der oberen Arteria basilaris.","author":"Bettag","year":"1996"},{"key":"b4","series-title":"J Neurosurg","first-page":"334A","article-title":"Long-term follow-up after GDC treatment of intracranial aneurysms: technical and hemodynamical considerations.","volume":"84","author":"Borchers","year":"1996"},{"key":"b5","series-title":"Br J Neurosurg","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1080\/02688699550040864","article-title":"Endosaccular treatment of inoperable intracranial aneurysms with platinum coils.","volume":"9","author":"Byrne","year":"1995"},{"key":"b6","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"3","DOI":"10.3171\/jns.1993.79.1.0003","article-title":"Selective endovascular treatment of 71 intracranial aneurysms with platinum coils.","volume":"79","author":"Casasco","year":"1993"},{"key":"b7","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1097\/00006123-199605000-00021","article-title":"Aneurysm clipping after endovascular treatment with coils: a report of eight patients.","volume":"38","author":"Civit","year":"1996"},{"key":"b8","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1227\/00006123-199501000-00017","article-title":"Treatment of experimental aneurysms using collagen-coated microcoils.","volume":"36","author":"Dawson","year":"1995"},{"key":"b9","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"230","DOI":"10.3171\/jns.1961.18.2.0230","article-title":"Bleeding aneurysms of the basilar artery. Direct surgical management in four cases.","volume":"18","author":"Drake","year":"1961"},{"key":"b10","series-title":"Clin Neurosurg","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1093\/neurosurgery\/26.CN_suppl_1.96","article-title":"The treatment of aneurysms of the posterior circulation.","volume":"26","author":"Drake","year":"1979"},{"key":"b11","series-title":"AJNR","first-page":"815","article-title":"Endovascular occlusion of intracranial aneurysms with electrically detachable coils: correlation of aneurysm neck size and treatment results.","volume":"15","author":"Fernandez Zubillaga","year":"1994"},{"key":"b12","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1227\/00006123-199510000-00006","article-title":"Early treatment of ruptured aneurysms with Guglielmi detachable coils: effect on subsequent bleeding.","volume":"37","author":"Graves","year":"1995"},{"key":"b13","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"1337","DOI":"10.1097\/00006123-199706000-00050","article-title":"A pitfall in the surgery of a recurrent aneurysm after coil embolization and its histological observation: technical case report.","volume":"40","author":"Guglielmi","year":"1997"},{"key":"b14","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"8","DOI":"10.3171\/jns.1991.75.1.0008","article-title":"Electrothrombosis of saccular aneurysms via endovascular approach. Part 2: Preliminary clinical experience.","volume":"75","author":"Guglielmi","year":"1991"},{"key":"b15","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"515","DOI":"10.3171\/jns.1992.77.4.0515","article-title":"Endovascular treatment of posterior circulation aneurysms by electrothrombosis using electrically detachable coils.","volume":"77","author":"Guglielmi","year":"1992"},{"key":"b16","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3171\/jns.1991.75.1.0001","article-title":"Electrothrombosis of saccular aneurysms via endovascular approach. Part 1: Electrochemical basis, technique, and experimental results.","volume":"75","author":"Guglielmi","year":"1991"},{"key":"b17","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"843","DOI":"10.3171\/jns.1995.83.5.0843","article-title":"Neurosurgical management of cerebral aneurysms following unsuccessful or incomplete endovascular embolization.","volume":"83","author":"Gurian","year":"1995"},{"key":"b18","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1227\/00006123-199211000-00005","article-title":"Management outcome for vertebrobasilar aneurysms by early surgery.","volume":"31","author":"Hernesniemi","year":"1992"},{"key":"b19","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"512","DOI":"10.3171\/jns.1989.71.4.0512","article-title":"Detachable balloon embolization therapy of posterior circulation intracranial aneurysms.","volume":"71","author":"Higashida","year":"1989"},{"key":"b20","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"33","DOI":"10.3171\/jns.1996.85.1.0033","article-title":"Overall management outcome of ruptured posterior fossa aneurysms.","volume":"85","author":"Hillman","year":"1996"},{"key":"b21","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"14","DOI":"10.3171\/jns.1968.28.1.0014","article-title":"Surgical risk as related to time of intervention in the repair of intracranial aneurysms.","volume":"28","author":"Hunt","year":"1968"},{"key":"b22","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"848","DOI":"10.3171\/jns.1992.77.6.0848","article-title":"Treatment of cerebral vasospasm with intra-arterial papaverine.","volume":"77","author":"Kassell","year":"1992"},{"key":"b23","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1227\/00006123-198209000-00001","article-title":"Treatment of ischemic deficits from vasospasm with intravascular volume expansion and induced arterial hypertension.","volume":"11","author":"Kassell","year":"1982"},{"key":"b24","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1227\/00006123-198311000-00001","article-title":"Aneurysmal rebleeding: a preliminary report from the Cooperative Aneurysm Study.","volume":"13","author":"Kassell","year":"1983"},{"key":"b25","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"176","DOI":"10.3171\/jns.1997.87.2.0176","article-title":"Intracranial aneurysms treated with the Guglielmi detachable coil: midterm clinical results in a consecutive series of 100 patients.","volume":"87","author":"Malisch","year":"1997"},{"key":"b26","series-title":"AJNR","first-page":"549","article-title":"Endovascular treatment of multiple aneurysms involving the posterior intracranial circulation.","volume":"17","author":"Massoud","year":"1996"},{"key":"b27","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"393","DOI":"10.3171\/jns.1996.84.3.0393","article-title":"Endovascular treatment of basilar tip aneurysms using electrolytically detachable coils.","volume":"84","author":"McDougall","year":"1996"},{"key":"b28","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"129","DOI":"10.3171\/jns.1995.83.1.0129","article-title":"Histological findings in giant aneurysms treated with Guglielmi detachable coils. Report of two cases with autopsy correlation.","volume":"83","author":"Molyneux","year":"1995"},{"key":"b29","series-title":"Int Neuroradiol","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1177\/159101999700300103","article-title":"The \u201cremodelling technique\u201d in the treatment of wide neck intracranial aneurysms. Angiographic results and clinical follow-up in 56 cases.","volume":"3","author":"Moret","year":"1997"},{"key":"b30","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3171\/jns.1993.79.1.0001","article-title":"Endovascular treatment of the acutely ruptured intracranial aneurysm.","volume":"79","author":"Nichols","year":"1993"},{"key":"b31","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"374","DOI":"10.3171\/jns.1997.87.3.0374","article-title":"Endovascular treatment of ruptured posterior circulation aneurysms using electolytically detachable coils.","volume":"87","author":"Nichols","year":"1997"},{"key":"b32","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"643","DOI":"10.3171\/jns.1994.80.4.0643","article-title":"Early surgery for ruptured vertebrobasilar aneurysms.","volume":"80","author":"Peerless","year":"1994"},{"key":"b33","series-title":"Neurosurgery","first-page":"948","article-title":"Selective occlusion of basilar artery aneurysms using controlled detachable coils: report of 35 cases.","volume":"38","author":"Pierot","year":"1997"},{"key":"b34","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"211","DOI":"10.3171\/jns.1997.86.2.0211","article-title":"Endovascular treatment of acutely ruptured and unruptured aneurysms of the basilar bifurcation.","volume":"86","author":"Raymond","year":"1997"},{"key":"b35","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"836","DOI":"10.3171\/jns.1997.87.6.0836","article-title":"Management-related morbidity in unselected aneurysms of the upper basilar artery.","volume":"87","author":"Redekop","year":"1997"},{"key":"b36","series-title":"AJNR","first-page":"35","article-title":"Long-term angiographic and histopathologic findings in experimental aneurysms of the carotid bifurcation embolized with platinum and tungsten coils.","volume":"18","author":"Reul","year":"1997"},{"key":"b37","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"165","DOI":"10.3171\/jns.1990.73.2.0165","article-title":"Surgical treatment of unruptured aneurysms of the posterior circulation.","volume":"73","author":"Rice","year":"1990"},{"key":"b38","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"791","DOI":"10.3171\/jns.1995.82.5.0791","article-title":"The poor prognosis of ruptured intracranial aneurysms of the posterior circulation.","volume":"82","author":"Schievink","year":"1995"},{"key":"b39","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1227\/00006123-198808000-00013","article-title":"Surgical approaches to aneurysms of the vertebral and basilar arteries.","volume":"23","author":"Solomon","year":"1988"},{"key":"b40","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"868","DOI":"10.3171\/jns.1988.68.6.0868","article-title":"Aneurysms of the basilar artery treated with circulatory cardiac arrest, hypothermia, and barbiturate cerebral protection.","volume":"68","author":"Spetzler","year":"1988"},{"key":"b41","series-title":"Surgical Techniques for Saccular and Giant Intracranial Aneurysms.","author":"Sundt","year":"1990"},{"key":"b42","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"475","DOI":"10.3171\/jns.1997.86.3.0475","article-title":"Guglielmi detachable coil embolization of acute intracranial aneurysm: perioperative anatomical and clinical outcome in 403 patients.","volume":"86","author":"Vi\u00f1uela","year":"1997"},{"key":"b43","series-title":"Microneurosurgery. Vol 2: Clinical Considerations, Surgery of the Intracranial Aneurysms and Results.","first-page":"232","author":"Ya\u015fargil","year":"1984"},{"key":"b44","series-title":"Acta Neurochir","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1007\/BF01808693","article-title":"Balloon embolization in the treatment of basilar aneurysms.","volume":"78","author":"Zeumer","year":"1985"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/90\/5\/article-p843.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/90\/5\/article-p843.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/90\/5\/article-p843.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T11:16:08Z","timestamp":1679915768000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/90\/5\/article-p843.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,5]]},"references-count":44,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.3171\/jns.1999.90.5.0843","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[1999,5]]}}}