{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T13:55:04Z","timestamp":1788357304068,"version":"build-2803163510"},"reference-count":36,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1999,9]]},"abstract":"<jats:p content-type=\"fine-print\"><jats:italic>Object.<\/jats:italic> The authors examined the relationships of brain\u2014tumor interfaces, specific magnetic resonance (MR) imaging features, and angiographic findings in meningiomas to predict tumor cleavage and difficulty of resection.<\/jats:p><jats:p content-type=\"fine-print\"><jats:italic>Methods.<\/jats:italic> Magnetic resonance imaging studies, angiographic data, operative reports, clinical data, and histopathological findings were examined retrospectively in this series, which included 126 patients with intracranial meningiomas who underwent operations in which microsurgical techniques were used. The authors have identified three kinds of brain\u2014tumor interfaces characterized by various difficulties in microsurgical dissection: smooth type, intermediate type, and invasive type. The signal intensity on T<jats:sub>1<\/jats:sub>-weighted MR images was very similar regardless of the type of brain\u2014tumor interface (p &gt; 0.1). However, on T<jats:sub>2<\/jats:sub>-weighted images the different interfaces seemed to correlate very precisely with the signal intensity and the amount of peritumoral edema (p &lt; 0.01), allowing the prediction of microsurgical effort required during surgery. On angiographic studies, the pial\u2014cortical arterial supply was seen to participate almost equally with the meningeal\u2014dural arterial supply in vascularizing the tumor in 57.9% of patients. Meningiomas demonstrating hypervascularization on angiography, particularly those fed by the pial\u2014cortical arteries, exhibited significantly more severe edema compared with those supplied only from meningeal arteries (p &lt; 0.01). Indeed, a positive correlation was found between the vascular supply from pial\u2014cortical arteries and the type of cleavage (p &lt; 0.05).<\/jats:p><jats:p content-type=\"fine-print\"><jats:italic>Conclusions.<\/jats:italic> In this analysis the authors proved that there is a strong correlation between the amount of peritumoral edema, hyperintensity of the tumor on T<jats:sub>2<\/jats:sub>-weighted images, cortical penetration, vascular supply from pial\u2014cortical arteries, and cleavage of the meningioma. Therefore, the consequent difficulty of microsurgical dissection can be predicted preoperatively by analyzing MR imaging and angiographic studies.<\/jats:p>","DOI":"10.3171\/jns.1999.91.3.0384","type":"journal-article","created":{"date-parts":[[2009,5,13]],"date-time":"2009-05-13T17:21:15Z","timestamp":1242235275000},"page":"384-390","source":"Crossref","is-referenced-by-count":75,"title":["Correlation of the relationships of brain\u2014tumor interfaces, magnetic resonance imaging, and angiographic findings to predict cleavage of meningiomas"],"prefix":"10.3171","volume":"91","author":[{"given":"Faruk","family":"\u0130ldan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Metin","family":"Tuna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alp \u0130skender","family":"G\u00f6cer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00fclent","family":"Boyar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00fcseyin","family":"Ba\u011fdato\u011flu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orhan","family":"\u015een","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebahattin","family":"Haciyakupo\u011flu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. Refik","family":"Burgut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"51","DOI":"10.3171\/jns.1983.58.1.0051","article-title":"The recurrence of intracranial meningiomas after surgical treatment.","volume":"58","author":"Adegbite","year":"1983"},{"key":"b2","series-title":"Meningiomas.","author":"Al-Mefty","year":"1991"},{"key":"b3","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1227\/00006123-198705000-00003","article-title":"Malignant and atypical meningiomas: a reappraisal of clinical, histological, and computed tomographic features.","volume":"20","author":"Alvarez","year":"1987"},{"key":"b4","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1227\/00006123-198808000-00007","article-title":"Correlation between sex hormone binding and peritumoral edema in intracranial meningiomas.","volume":"23","author":"Benzel","year":"1988"},{"key":"b5","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1097\/00006123-199304000-00023","article-title":"Meningiomas.","volume":"32","author":"Black","year":"1993"},{"key":"b6","series-title":"J Comput Assist Tomogr","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1097\/00004728-198507010-00006","article-title":"MR imaging of meningiomas including studies with and without gadolinium-DTPA.","volume":"9","author":"Bydder","year":"1985"},{"key":"b7","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1227\/00006123-198010000-00009","article-title":"The vascular component in meningiomas associated with severe cerebral edema.","volume":"7","author":"Challa","year":"1980"},{"key":"b8","series-title":"Neurosurgery","first-page":"1015","article-title":"Magnetic resonance imaging and pathological correlates of meningiomas.","volume":"31","author":"Chen","year":"1992"},{"key":"b9","series-title":"J Comput Assist Tomogr","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1097\/00004728-199101000-00005","article-title":"Intracranial meningiomas: correlation between MR imaging and histology in fifty patients.","volume":"15","author":"Demaerel","year":"1991"},{"key":"b10","series-title":"Oncology (Huntingt)","first-page":"83","article-title":"Current management of meningiomas.","volume":"9","author":"De Monte","year":"1995"},{"key":"b11","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1148\/radiology.170.3.2916043","article-title":"Meningiomas: MR and histopathologic features.","volume":"170","author":"Elster","year":"1989"},{"key":"b12","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"545","DOI":"10.3171\/jns.1990.73.4.0545","article-title":"Growth rate of incidental meningiomas.","volume":"73","author":"Firsching","year":"1990"},{"key":"b13","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"70","DOI":"10.3171\/jns.1979.51.1.0070","article-title":"Composition of isolated edema fluid in cold-induced edema.","volume":"51","author":"Gazendam","year":"1979"},{"key":"b14","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1227\/00006123-198808000-00008","article-title":"Peritumoral brain edema associated with meningiomas.","volume":"23","author":"Go","year":"1988"},{"key":"b15","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1148\/radiology.166.3.3340779","article-title":"Sensitivity of Gd-DTPA-enhanced MR imaging of benign extraaxial tumors.","volume":"166","author":"Haughton","year":"1988"},{"key":"b16","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1227\/00006123-199004000-00009","article-title":"Metabolic and hemodynamic aspects of peritumoral low-density areas in human brain tumor.","volume":"26","author":"Hino","year":"1990"},{"key":"b17","series-title":"Cancer","doi-asserted-by":"publisher","first-page":"1466","DOI":"10.1002\/1097-0142(19861001)58:7<1466::AID-CNCR2820580715>3.0.CO;2-W","article-title":"Proliferative potential of human meningiomas of the brain. A cell kinetics study with bromodeoxyuridine.","volume":"58","author":"Hoshino","year":"1986"},{"key":"b18","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1227\/00006123-199208000-00002","article-title":"Peritumoral brain edema in meningiomas\u2014influence of vascular supply on its development.","volume":"31","author":"Inamura","year":"1992"},{"key":"b19","series-title":"J Neurol","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1007\/BF00312803","article-title":"Histological subtypes and prognostic problems in meningiomas.","volume":"208","author":"Jellinger","year":"1975"},{"key":"b20","series-title":"Neurosurgery","first-page":"2","article-title":"Factors affecting operative and excess long-term mortality in 935 patients with intracranial meningioma.","volume":"31","author":"Kallio","year":"1992"},{"key":"b21","series-title":"J Comput Assist Tomogr","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1097\/00004728-199205000-00006","article-title":"MR characteristics of meningioma subtypes at 1.5 tesla.","volume":"16","author":"Kaplan","year":"1992"},{"key":"b22","series-title":"Brain Edema.","first-page":"484","article-title":"Influence of peritumoral edema on rCBF and on cerebral function: analysis by xenon-enhanced CT and EEG topography","author":"Kawase","year":"1985"},{"key":"b23","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"187","DOI":"10.3171\/jns.1994.80.2.0187","article-title":"Contemporary management of meningiomas: radiation therapy as an adjuvant and radiosurgery as an alternative to surgical removal?","volume":"80","author":"Lunsford","year":"1994"},{"key":"b24","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"202","DOI":"10.3171\/jns.1994.80.2.0202","article-title":"Recurrent spheno-orbital meningioma.","volume":"80","author":"Maroon","year":"1994"},{"key":"b25","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"18","DOI":"10.3171\/jns.1985.62.1.0018","article-title":"Meningioma: analysis of recurrence and progression following neurosurgical resection.","volume":"62","author":"Mirimanoff","year":"1985"},{"key":"b26","series-title":"Pathology of Tumours of the Nervous System","first-page":"449","author":"Russell","year":"1989"},{"key":"b27","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1227\/00006123-199410000-00009","article-title":"Peritumoral edema in meningiomas: microsurgical observations of different brain tumor interfaces related to computed tomography.","volume":"35","author":"Salpietro","year":"1994"},{"key":"b28","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"860","DOI":"10.3171\/jns.1994.81.6.0860","article-title":"Surgical excision of meningiomas involving the clivus: preoperative and intraoperative features as predictors of postoperative functional deterioration.","volume":"81","author":"Sekhar","year":"1994"},{"key":"b29","series-title":"J Neurol Neurosurg Psychiatry","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1136\/jnnp.20.1.22","article-title":"The recurrence of intracranial meningiomas after surgical treatment.","volume":"20","author":"Simpson","year":"1957"},{"key":"b30","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1097\/00006123-199803000-00007","article-title":"Most intracranial meningiomas are not cleavable tumors: anatomic-surgical evidence and angiographic predictability.","volume":"42","author":"Sindou","year":"1998"},{"key":"b31","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1148\/radiology.161.2.3763903","article-title":"Intracranial meningiomas: high-field MR imaging.","volume":"161","author":"Spagnoli","year":"1986"},{"key":"b32","series-title":"Neuroradiology","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1007\/BF00455731","article-title":"Observations on peritumoural oedema in meningioma. Part II. Mechanisms of oedema production.","volume":"25","author":"Stevens","year":"1983"},{"key":"b33","series-title":"AJNR","first-page":"463","article-title":"T1 and T2 measurements of meningiomas and neuromas before and after Gd-DTPA.","volume":"10","author":"Watabe","year":"1989"},{"key":"b34","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"666","DOI":"10.3171\/jns.1994.81.5.0666","article-title":"Meningiomas: genetics malignancy, and the role of radiation in induction and treatment. The Richard C. Schneider Lecture.","volume":"81","author":"Wilson","year":"1994"},{"key":"b35","series-title":"Surg Neurol","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1016\/S0090-3019(96)00439-9","article-title":"Prediction of consistency of meningiomas with preoperative magnetic resonance imaging.","volume":"48","author":"Yamaguchi","year":"1997"},{"key":"b36","series-title":"AJNR","first-page":"149","article-title":"Magnetic resonance imaging of meningiomas.","volume":"6","author":"Zimmerman","year":"1985"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/91\/3\/article-p384.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/91\/3\/article-p384.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/91\/3\/article-p384.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T01:51:17Z","timestamp":1679881877000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/91\/3\/article-p384.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,9]]},"references-count":36,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.3171\/jns.1999.91.3.0384","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[1999,9]]}}}