{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T04:39:51Z","timestamp":1780720791676,"version":"3.54.1"},"reference-count":12,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,2]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 Intrathecal baclofen administered by means of an implantable pump is being increasingly used for successful treatment of spasticity. Meningitis following intrathecally administered baclofen is a rare but serious complication that is difficult to treat without removal of the pump. Because success rates with intravenously administered antibiotic drugs for the treatment of meningitis have been low, intrathecal administration of antibiotic agents is often required to eradicate the pathogen. The authors report the case of a patient in whom <jats:italic>Staphylococcus epidermidis<\/jats:italic> meningitis developed after insertion of an intrathecal baclofen pump. The patient was successfully treated by intrathecal coadministration of vancomycin and baclofen.<\/jats:p>","DOI":"10.3171\/jns.2000.92.2.0347","type":"journal-article","created":{"date-parts":[[2009,5,13]],"date-time":"2009-05-13T17:33:09Z","timestamp":1242235989000},"page":"347-349","source":"Crossref","is-referenced-by-count":44,"title":["Continuous intrathecal pump infusion of baclofen with antibiotic drugs for treatment of pump-associated meningitis"],"prefix":"10.3171","volume":"92","author":[{"given":"Peter J.","family":"Zed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. grant","family":"Stiver","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia","family":"Devonshire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Jewesson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fawziah","family":"Marra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"934","DOI":"10.1097\/00006123-199605000-00015","article-title":"Continuous intrathecal baclofen infusion for symptomatic generalized dystonia.","volume":"38","author":"Albright","year":"1996"},{"key":"b2","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"409","DOI":"10.3171\/jns.1997.87.3.0409","article-title":"Intrathecally administered baclofen for treatment of children with spasticity of cerebral origin.","volume":"87","author":"Armstrong","year":"1997"},{"key":"b3","series-title":"Pain","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/0304-3959(94)90100-7","article-title":"Staphylococcal meningitis following Synchromed intrathecal pump implant: a case report.","volume":"56","author":"Bennett","year":"1994"},{"key":"b4","series-title":"Neurology","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1212\/WNL.44.1.25","article-title":"Epileptic seizures associated with intrathecal baclofen application.","volume":"44","author":"Kofler","year":"1994"},{"key":"b5","series-title":"Clin Drug Invest","doi-asserted-by":"publisher","first-page":"105","DOI":"10.2165\/00044011-199612020-00006","article-title":"Vancomycin serum concentration monitoring. 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