{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:48:32Z","timestamp":1787320112859,"version":"build-2736575974"},"reference-count":21,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,6]]},"abstract":"<jats:p content-type=\"fine-print\">\n                    <jats:italic>Object.<\/jats:italic>\n                    The goal of this study was to determine and compare imaging correlates in pediatric patients who underwent successful or failed endoscopic third ventriculostomies (ETVs). To this end, the authors measured ventricular size changes and the presence of cerebrospinal fluid (CSF) flow void in both groups of children following ETV.\n                  <\/jats:p>\n                  <jats:p content-type=\"fine-print\">\n                    <jats:italic>Methods.<\/jats:italic>\n                    Images obtained in children with hydrocephalus immediately before and at least 30 days after having undergone ETV were reviewed by four independent observers (two blinded and two nonblinded). Each observer independently measured the frontal and occipital horn ratio ([FOR], a reliable and valid measure of ventricular size) and provided a subjective assessment of the presence of a flow void at the ETV site, the degree of periventricular edema, and the amount of CSF over the cerebral hemispheres.\n                  <\/jats:p>\n                  <jats:p content-type=\"fine-print\">There were 29 children whose mean age was 6.6 years at the time of ETV and who had a mean postoperative follow-up period lasting 1.6 years. Postoperatively, the mean reduction in ventricular size (as measured using the FOR) was 7% (95% confidence interval [CI] 3\u201311%) in cases that were deemed failures (eight patients) and 16% (95% CI 12\u201320%) in clinically successful cases (21 patients). This reduction was significantly greater in cases of clinical success compared with those that were deemed failures (p = 0.03, t-test). There were no substantial differences between blinded and nonblinded assessments. Flow void was present in 94% of successes and absent in 75% of failures (p = 0.01, Fisher's exact test). The other subjective assessments were not significantly different between the groups of successes and failures.<\/jats:p>\n                  <jats:p content-type=\"fine-print\">\n                    <jats:italic>Conclusions.<\/jats:italic>\n                    Ventricular size appears to be somewhat reduced in both groups of patients who underwent clinically successful and failed ETV; however, the reduction is significantly greater among clinically successful cases. The presence of a flow void also appears to correlate with clinical success and its absence with clinical failure.\n                  <\/jats:p>","DOI":"10.3171\/jns.2000.92.6.0915","type":"journal-article","created":{"date-parts":[[2009,5,13]],"date-time":"2009-05-13T13:31:09Z","timestamp":1242221469000},"page":"915-919","source":"Crossref","is-referenced-by-count":115,"title":["Imaging correlates of successful endoscopic third ventriculostomy"],"prefix":"10.3171","volume":"92","author":[{"given":"Abhaya V.","family":"Kulkarni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James M.","family":"Drake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek C.","family":"Armstrong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter B.","family":"Dirks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Pediatr Neurosurg","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1159\/000028693","article-title":"Neuroendoscopic third ventriculostomy in patients less than 1 year old.","volume":"29","author":"Buxton","year":"1998"},{"key":"b2","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"448","DOI":"10.3171\/jns.1999.90.3.0448","article-title":"Failure of third ventriculostomy in the treatment of aqueductal stenosis in children.","volume":"90","author":"Cinalli","year":"1999"},{"key":"b3","series-title":"Neurosurgery","first-page":"1323","article-title":"The role of endoscopic third ventriculostomy in the management of shunt malfunction.","volume":"43","author":"Cinalli","year":"1998"},{"key":"b4","series-title":"Stereotact Funct Neurosurg","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1159\/000098925","article-title":"Computer-assisted stereotactic third ventriculostomy in the management of noncommunicating hydrocephalus.","volume":"59","author":"Dalrymple","year":"1992"},{"key":"b5","series-title":"Pediatr Neurosurg","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1159\/000121242","article-title":"Treatment of hydrocephalus with third ventriculocisternostomy: outcome and CSF flow pattern.","volume":"27","author":"Goumnerova","year":"1997"},{"key":"b6","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1227\/00006123-198010000-00002","article-title":"Percutaneous third ventriculostomy in the management of noncommunicating hydrocephalus.","volume":"7","author":"Hoffman","year":"1980"},{"key":"b7","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1097\/00006123-199904000-00062","article-title":"Endoscopic third ventriculostomy: outcome analysis of 100 consecutive procedures.","volume":"44","author":"Hopf","year":"1999"},{"key":"b8","series-title":"AJNR","first-page":"515","article-title":"Stereotactic third ventriculostomy: assessment of patency with MR imaging.","volume":"10","author":"Jack","year":"1989"},{"key":"b9","series-title":"Acta Neurochir","first-page":"48","article-title":"Burr hole third ventriculo-cisternostomy. An unpopular but effective procedure for treatment of certain forms of occlusive hydrocephalus.","volume":"79","author":"Jaksche","year":"1986"},{"key":"b10","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"865","DOI":"10.3171\/jns.1991.75.6.0865","article-title":"Stereotactic third ventriculostomy in patients with nontumoral adolescent\/adult onset aqueductal stenosis and symptomatic hydrocephalus.","volume":"75","author":"Kelly","year":"1991"},{"key":"b11","series-title":"Pediatr Neurosurg","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1159\/000028836","article-title":"Measurement of ventricular size: reliability of the frontal and occipital horn ratio compared to subjective assessment.","volume":"31","author":"Kulkarni","year":"1999"},{"key":"b12","series-title":"Neuroradiology","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1007\/s002340050387","article-title":"Functional analysis of third ventriculostomy patency with phase-contrast MRI velocity measurements.","volume":"39","author":"Lev","year":"1997"},{"key":"b13","series-title":"Neurochirurgie","first-page":"361","article-title":"La ventriculocisternostomie ster\u00e9otaxique dans le traitement de l'hydroc\u00e9phalie obstructive triventriculaire. A propos de 23 cas.","volume":"34","author":"Musolino","year":"1988"},{"key":"b14","series-title":"Pediatr Neurosurg","first-page":"245","article-title":"Frontal and occipital horn ratio: a linear estimate of ventricular size for multiple imaging modalities in pediatric hydrocephalus.","volume":"29","author":"O'Hayon","year":"1999"},{"key":"b15","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1097\/00006123-199308000-00009","article-title":"Flexible endoneurosurgical therapy for aqueductal stenosis.","volume":"33","author":"Oka","year":"1993"},{"key":"b16","series-title":"Minim Invasive Neurosurg","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1055\/s-2008-1052209","article-title":"Ultrasound-guided endoscopic fenestration of the third ventricular floor for non-communicating hydrocephalus.","volume":"39","author":"Rieger","year":"1996"},{"key":"b17","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"20","DOI":"10.3171\/jns.1999.91.1.0020","article-title":"Ventricular volume following third ventriculostomy.","volume":"91","author":"Schwartz","year":"1999"},{"key":"b18","series-title":"Minim Invasive Neurosurg","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1055\/s-2008-1052231","article-title":"Third ventriculostomy: postoperative ventricular size and outcome.","volume":"39","author":"Schwartz","year":"1996"},{"key":"b19","series-title":"Pediatr Neurosurg","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1159\/000121098","article-title":"Management of hydrocephalus by endoscopic third ventriculostomy in patients with myelomeningocele.","volume":"25","author":"Teo","year":"1996"},{"key":"b20","series-title":"Clin Radiol","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/S0009-9260(97)80306-6","article-title":"Neuro-endoscopic third ventriculostomy: evaluation with magnetic resonance imaging.","volume":"52","author":"Wilcock","year":"1997"},{"key":"b21","series-title":"Minim Invasive Neurosurg","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1055\/s-2008-1052040","article-title":"Variations in the site and size of third ventriculocisternostomy.","volume":"41","author":"Zohdi","year":"1998"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/92\/6\/article-p915.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/92\/6\/article-p915.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/92\/6\/article-p915.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T01:05:53Z","timestamp":1679879153000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/92\/6\/article-p915.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,6]]},"references-count":21,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.3171\/jns.2000.92.6.0915","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[2000,6]]}}}