{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T12:49:06Z","timestamp":1760186946176},"reference-count":6,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2002,7]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 A 23-year-old patient who was examined in 1910 by Harvey Cushing triggered his lifelong interest in the syndrome that bears his name. \u201cMinnie G.,\u201d as she became historically known, presented with a \u201c\u2026 syndrome of painful obesity, hypertrichosis, and amenorrhea with overdevelopment of secondary sexual characteristics accompanying a low grade of hydrocephalus and increased cerebral tension.\u201d This case stimulated Harvey Cushing's inquisitive mind and sparked an interest that 20 years later culminated in his seminal report, \u201cThe basophil adenomas of the pituitary gland and their clinical manifestations (pituitary basophilism).\u201d In this classic work, Cushing reported in detail the cases of two patients encountered from his own practice and 10 similar cases collected from the literature. Minnie G. was the first case that Cushing reported. The clinical course of that case is briefly reviewed in this article.<\/jats:p>","DOI":"10.3171\/jns.2002.97.1.0231","type":"journal-article","created":{"date-parts":[[2009,5,13]],"date-time":"2009-05-13T17:47:43Z","timestamp":1242236863000},"page":"231-234","source":"Crossref","is-referenced-by-count":19,"title":["Cushing's Case XLV: Minnie G."],"prefix":"10.3171","volume":"97","author":[{"given":"Giuseppe","family":"Lanzino","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niki F.","family":"Maartens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward R.","family":"Laws","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Am J Surg Pathol","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1097\/00000478-199501000-00012","article-title":"The search for Harvey Cushing's patient, Minnie G., and the cause of her hypercortisolism.","volume":"19","author":"Carney","year":"1995"},{"key":"b2","series-title":"Medicine","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1097\/00005792-198507000-00007","article-title":"The complex of myxomas, spotty pigmentation and endocrine overactivity.","volume":"64","author":"Carney","year":"1985"},{"key":"b3","series-title":"Bull Johns Hopkins Hosp","first-page":"137","article-title":"The basophil adenomas of the pituitary body and their clinical manifestations (pituitary basophilism).","volume":"50","author":"Cushing","year":"1932"},{"key":"b4","series-title":"The Pituitary Body and its Disorders: Clinical States Produced by Disorders of the Hypophysis Cerebri.","author":"Cushing","year":"1912"},{"key":"b5","series-title":"Beitr Pathol Anat","first-page":"158","article-title":"Zur normalen und pathologischen Histologie der Glandula thyreoidea, parathyreoidea und Hypophysis.","volume":"33","author":"Erdheim","year":"1903"},{"key":"b6","series-title":"Harvey Cushing. A Biography.","author":"Fulton","year":"1946"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/97\/1\/article-p231.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/97\/1\/article-p231.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/97\/1\/article-p231.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T01:15:35Z","timestamp":1679274935000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/97\/1\/article-p231.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,7]]},"references-count":6,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.3171\/jns.2002.97.1.0231","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[2002,7]]}}}