{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T22:11:11Z","timestamp":1770675071593,"version":"3.49.0"},"reference-count":38,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004,5]]},"abstract":"<jats:p content-type=\"fine-print\"><jats:italic>Object.<\/jats:italic> Allergic fungal sinusitis (AFS) is a form of paranasal mycosis that often involves bone destruction and extension into the orbit and anterior skull base. Treatment consists of surgical extirpation and a course of corticosteroids. Despite frequent intracranial involvement, AFS is rarely reported in the neurosurgical literature.<\/jats:p>\n<jats:p content-type=\"fine-print\"><jats:italic>Methods.<\/jats:italic> The records of 21 patients with the histological diagnosis of AFS were reviewed. The histological diagnosis was based on findings of branching septated fungi interspersed with eosinophilic mucin and Charcot\u2014Leyden crystals without fungal invasion of soft tissue.<\/jats:p>\n<jats:p content-type=\"fine-print\">The average age of the 21 patients in this study was 25 years (range 9\u201346) and the male\/female ratio was 3.75:1. All patients were immunocompetent. All had a history of chronic sinusitis and imaging findings of expansile disease involving multiple sinuses. Fifteen patients had nasal polyposis, eight had erosion of bone, which was observed on computerized tomography (CT) scans, eight had disease extending intracranially, and six had disease that involved the lamina papyracea. All patients underwent transnasal and\/or transmaxillary endoscopic approaches for debridement and irrigation, six underwent orbital decompression, and three underwent a bifrontal craniotomy for removal of intracranial extradural disease. No patient had a cerebrospinal fluid leak. Postoperatively, one patient was treated with amphotericin B and the other 20 were treated with a short course of corticosteroids. The follow-up period ranged from 2 to 19 years.<\/jats:p>\n<jats:p content-type=\"fine-print\"><jats:italic>Conclusions.<\/jats:italic> Allergic fungal sinusitis is a unique form of fungal disease that may mimic anterior skull base and paranasal sinus tumors. A cranial base team approach of neurosurgeons and otolaryngologists is recommended. Most cases can be successfully managed with transnasal and\/or transmaxillary endoscopic techniques. A craniotomy is rarely indicated unless there is the suspicion of dural invasion or extensive intracranial and\/or intraorbital involvement that is inaccessible from below.<\/jats:p>","DOI":"10.3171\/jns.2004.100.5.0883","type":"journal-article","created":{"date-parts":[[2009,5,13]],"date-time":"2009-05-13T17:57:45Z","timestamp":1242237465000},"page":"883-890","source":"Crossref","is-referenced-by-count":23,"title":["Neurosurgical implications of allergic fungal sinusitis"],"prefix":"10.3171","volume":"100","author":[{"given":"James K.","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven D.","family":"Schaefer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Augustine L.","family":"Moscatello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William T.","family":"Couldwell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1086\/313938","volume":"31","author":"Andes D","year":"2000","journal-title":"Clin Infect Dis"},{"key":"b2","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1097\/00005537-199611000-00005","volume":"106","author":"Bent JP","year":"1996","journal-title":"Laryngoscope"},{"key":"b3","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0002-9394(98)00371-7","volume":"127","author":"Carter KD","year":"1999","journal-title":"Am J Ophthalmol"},{"key":"b4","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0030-6665(20)31026-4","volume":"25","author":"Corey JP","year":"1992","journal-title":"Otolaryngol Clin North Am"},{"key":"b5","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1017\/S0022215100120912","volume":"106","author":"Daghistani KJ","year":"1992","journal-title":"J Laryngol Otol"},{"key":"b6","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1056\/NEJM199707243370407","volume":"337","author":"deShazo RD","year":"1997","journal-title":"N Engl J Med"},{"key":"b7","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S0091-6749(95)70029-3","volume":"96","author":"deShazo RD","year":"1995","journal-title":"J Allergy Clin Immunol"},{"key":"b8","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1097\/00005537-200005000-00010","volume":"110","author":"Ferguson BJ","year":"2000","journal-title":"Laryngoscope"},{"key":"b9","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/S0030-6665(00)80018-3","volume":"33","author":"Ferguson BJ","year":"2000","journal-title":"Otolaryngol Clin North Am"},{"key":"b10","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1067\/mai.2000.109269","volume":"106","author":"Hamilos DL","year":"2000","journal-title":"J Allergy Clin Immunol"},{"key":"b11","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/S0030-6665(00)80014-6","volume":"33","author":"Houser SM","year":"2000","journal-title":"Otolaryngol Clin North Am"},{"key":"b12","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0091-6749(83)90057-X","volume":"72","author":"Katzenstein AL","year":"1983","journal-title":"J Allergy Clin Immunol"},{"key":"b13","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1097\/00000478-198307000-00006","volume":"7","author":"Katzenstein AL","year":"1983","journal-title":"Am J Surg Pathol"},{"key":"b14","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1002\/(SICI)1097-0347(199605\/06)18:3<211::AID-HED1>3.0.CO;2-2","volume":"18","author":"Kinsella JB","year":"1996","journal-title":"Head Neck"},{"key":"b15","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1016\/S0161-6420(97)30054-2","volume":"104","author":"Klapper SR","year":"1997","journal-title":"Ophthalmology"},{"key":"b16","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0030-6665(00)80016-X","volume":"33","author":"Kuhn FA","year":"2000","journal-title":"Otolaryngol Clin North Am"},{"key":"b17","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1001\/archotol.1996.01890240087019","volume":"122","author":"Kupferberg SB","year":"1996","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"b18","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000088802.58956.5A"},{"key":"b19","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1001\/archotol.1993.01880210136019","volume":"119","author":"Loury MC","year":"1993","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"b20","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1177\/014556139407300610","volume":"73","author":"Lydiatt WM","year":"1994","journal-title":"Ear Nose Throat J"},{"key":"b21","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/S0030-6665(00)80017-1","volume":"33","author":"Mabry RL","year":"2000","journal-title":"Otolaryngol Clin North Am"},{"key":"b22","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/S0194-5998(00)70153-7","volume":"122","author":"Mabry RL","year":"2000","journal-title":"Otolaryngol Head Neck Surg"},{"key":"b23","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1097\/00005537-199810000-00012","volume":"108","author":"Manning SC","year":"1998","journal-title":"Laryngoscope"},{"key":"b24","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1288\/00005537-199307000-00002","volume":"103","author":"Manning SC","year":"1993","journal-title":"Laryngoscope"},{"key":"b25","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1097\/00005537-199702000-00007","volume":"107","author":"Manning SC","year":"1997","journal-title":"Laryngoscope"},{"key":"b26","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1001\/archotol.1991.01870140062007","volume":"117","author":"Manning SC","year":"1991","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"b27","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1288\/00005537-198907000-00003","volume":"99","author":"Manning SC","year":"1989","journal-title":"Laryngoscope"},{"key":"b28","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1097\/00005537-200106000-00015","volume":"111","author":"Marple BF","year":"2001","journal-title":"Laryngoscope"},{"key":"b29","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/S0030-6665(00)80015-8","volume":"33","author":"Marple BF","year":"2000","journal-title":"Otolaryngol Clin North Am"},{"key":"b30","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/S1081-1206(10)63411-4","volume":"76","author":"Morpeth JF","year":"1996","journal-title":"Ann Allergy Asthma Immunol"},{"key":"b31","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1148\/radiology.207.2.9577490","volume":"207","author":"Mukherji SK","year":"1998","journal-title":"Radiology"},{"key":"b32","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1067\/mhn.2001.112573","volume":"124","author":"Nussenbaum B","year":"2001","journal-title":"Otolaryngol Head Neck Surg"},{"key":"b33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1177\/194589240301700101","volume":"17","author":"Rains BM","year":"2003","journal-title":"Am J Rhinol"},{"key":"b34","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1111\/j.1445-5994.1989.tb00278.x","volume":"19","author":"Robson JM","year":"1989","journal-title":"Aust NZ J Med"},{"key":"b35","doi-asserted-by":"crossref","first-page":"343, 350","DOI":"10.1136\/pmj.77.907.343","volume":"77","author":"Rupa V","year":"2001","journal-title":"Postgrad Med J"},{"key":"b36","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1258\/0022215011907154","volume":"115","author":"Serrano E","year":"2001","journal-title":"J Laryngol Otol"},{"key":"b37","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1053\/ai.1994.v94.a52634","volume":"94","author":"Tsimikas S","year":"1994","journal-title":"J Allergy Clin Immunol"},{"key":"b38","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1288\/00005537-198703000-00001","volume":"97","author":"Waxman JE","year":"1987","journal-title":"Laryngoscope"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/100\/5\/article-p883.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/100\/5\/article-p883.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/100\/5\/article-p883.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,28]],"date-time":"2022-05-28T03:12:58Z","timestamp":1653707578000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/100\/5\/article-p883.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,5]]},"references-count":38,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.3171\/jns.2004.100.5.0883","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[2004,5]]}}}