{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T10:23:58Z","timestamp":1773829438084,"version":"3.50.1"},"reference-count":13,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004,5]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 The authors report on the case of a 37-year-old woman in whom a primary sellar malignant melanoma mimicking a hemorrhagic pituitary macroadenoma was treated. This entity is exceedingly rare; only five cases are described in the literature. The patient presented with rapid deterioration of vision within a 2-week period. After an ophthalmological diagnosis of chiasmal syndrome was made, magnetic resonance (MR) imaging of the head revealed an intra- and suprasellar mass that was elevating and compressing the optic chiasm. Because of the signal heterogeneity of the lesion a hemorrhagic pituitary macroadenoma was assumed; the lesion was transsphenoidally resected. Histological examination of the specimen showed a malignant melanocytic tumor with immunopositivity for S100 protein and HMB-45. Despite extensive staging no other primary melanotic tumor was found. Thus, a primary sellar melanoma was diagnosed. Postoperative MR images demonstrated no residual tumor. For adjuvant therapy the region around the sella turcica received 40.4 Gy stereotactically guided radiation. A 24-month follow-up examination revealed no tumor recurrence.<\/jats:p>\n<jats:p content-type=\"fine-print\">This represents the sixth case of such a lesion reported in the literature, the third case evaluated using MR imaging, and the first case with a progression-free survival of 24 months. Thus, the authors advocate that management of primary sellar melanoma should include gross-total removal and postoperative stereotactic radiotherapy.<\/jats:p>","DOI":"10.3171\/jns.2004.100.5.0931","type":"journal-article","created":{"date-parts":[[2009,5,13]],"date-time":"2009-05-13T17:57:45Z","timestamp":1242237465000},"page":"931-934","source":"Crossref","is-referenced-by-count":28,"title":["A rare case of primary sellar melanoma"],"prefix":"10.3171","volume":"100","author":[{"given":"Jochen","family":"T\u00fcttenberg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfram","family":"Fink","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter","family":"Back","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frederik","family":"Wenz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirk","family":"Schadendorf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudius","family":"Thom\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","doi-asserted-by":"publisher","DOI":"10.1080\/02688699746771"},{"key":"b2","first-page":"1054","volume":"11","author":"Chappell PM","year":"1990","journal-title":"AJNR"},{"key":"b3","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1227\/00006123-198005000-00008","volume":"6","author":"Copeland DD","year":"1980","journal-title":"Neurosurgery"},{"key":"b4","first-page":"1864","volume":"22","author":"Farrokh D","year":"2001","journal-title":"AJNR"},{"key":"b5","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1111\/j.1600-0749.1999.tb00766.x","volume":"12","author":"Fetissov SO","year":"1999","journal-title":"Pigment Cell Res"},{"key":"b6","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0090-3019(01)00348-2","volume":"55","author":"Greco Crasto S","year":"2001","journal-title":"Surg Neurol"},{"key":"b7","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1001\/archneur.1992.00530290147025","volume":"49","author":"Juneau P","year":"1992","journal-title":"Arch Neurol"},{"key":"b8","doi-asserted-by":"publisher","DOI":"10.3109\/02688698909001028"},{"key":"b9","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/S0360-3016(98)00272-7","volume":"42","author":"Mori Y","year":"1998","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"b10","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1998.89.1.0069"},{"key":"b11","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1136\/jcp.16.2.144","volume":"16","author":"Neilson JM","year":"1963","journal-title":"J Clin Pathol"},{"key":"b12","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1976.45.1.0101"},{"key":"b13","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-2388(199801\/02)14:1<70::AID-SSU9>3.0.CO;2-#"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/100\/5\/article-p931.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/100\/5\/article-p931.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/100\/5\/article-p931.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,28]],"date-time":"2022-05-28T03:12:27Z","timestamp":1653707547000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/100\/5\/article-p931.xml"}},"subtitle":["Case report"],"short-title":[],"issued":{"date-parts":[[2004,5]]},"references-count":13,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.3171\/jns.2004.100.5.0931","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[2004,5]]}}}