{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T11:40:03Z","timestamp":1771069203321,"version":"3.50.1"},"reference-count":20,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,1]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 The Wada test is still considered the gold standard for determining the language-dominant hemisphere prior to brain surgery. The authors report on a 34-year-old right-handed woman whose Wada test results indicated that the right hemisphere was dominant for language. In contrast, functional magnetic resonance (fMR) imaging was indicative of bilaterally represented language functions. Activation in the left hemisphere demonstrated on fMR imaging was most pronounced in the Broca area. Importantly, fMR imaging results in this area were confirmed on electrocortical stimulation mapping. These contradictory findings indicated that a right hemispherre dominance for language according to the Wada test should be questioned and verified using electrocortical stimulation. Nonetheless, the question remains whether involvement of these areas in the left frontal hemisphere is critical for language, as these were spared during surgery.<\/jats:p>","DOI":"10.3171\/jns.2005.102.1.0169","type":"journal-article","created":{"date-parts":[[2009,5,13]],"date-time":"2009-05-13T18:11:32Z","timestamp":1242238292000},"page":"169-173","source":"Crossref","is-referenced-by-count":28,"title":["Discrepant findings for Wada test and functional magnetic resonance imaging with regard to language function: use of electrocortical stimulation mapping to confirm results"],"prefix":"10.3171","volume":"102","author":[{"given":"Kuan H.","family":"Kho","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frans S. S.","family":"Leijten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geert-Jan","family":"Rutten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Vermeulen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"van Rijen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nick F.","family":"Ramsey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Epilepsy Res","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/S0920-1211(00)00097-8","article-title":"The wada test: prediction of focus lateralization by asymmetric and symmetric recall.","volume":"39","author":"Alpherts","year":"2000"},{"key":"b2","series-title":"Neurology","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1212\/WNL.46.4.978","article-title":"Determination of language dominance using functional MRI: a comparison with the Wada test.","volume":"46","author":"Binder","year":"1996"},{"key":"b3","series-title":"Acta Neurol Belg","first-page":"125","article-title":"Presurgical evaluation of patients with intractable partial epilepsy: the Dutch epilepsy surgery program.","volume":"91","author":"Debets","year":"1991"},{"key":"b4","series-title":"Boston Diagnostic Aphasia Examination (BDAE).","author":"Goodglass","year":"1983"},{"key":"b5","series-title":"Neurosurgery","first-page":"567","article-title":"Cortical localization of temporal lobe language sites in patients with gliomas.","volume":"34","author":"Haglund","year":"1994"},{"key":"b6","series-title":"Arch Neurol","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1001\/archneur.1991.00530130063021","article-title":"Dominant-side intracarotid amobarbital spares comprehension of word meaning.","volume":"48","author":"Hart","year":"1991"},{"key":"b7","series-title":"Ann Neurol","doi-asserted-by":"publisher","first-page":"662","DOI":"10.1002\/1531-8249(199905)45:5<662::AID-ANA17>3.0.CO;2-A","article-title":"(15)O water positron emission tomography in language localization: a study comparing positron emission tomography visual and computerized region of interest analysis with the Wada test.","volume":"45","author":"Hunter","year":"1999"},{"key":"b8","series-title":"Neuroreport","doi-asserted-by":"publisher","first-page":"3537","DOI":"10.1097\/00001756-199711100-00024","article-title":"Neuronal responses to magnetic stimulation reveal cortical reactivity and connectivity.","volume":"8","author":"Ilmoniemi","year":"1997"},{"key":"b9","series-title":"Comput Aided Surg","doi-asserted-by":"publisher","first-page":"241","DOI":"10.3109\/10929080109146090","article-title":"Localization of implanted EEG electrodes in a virtual-reality environment.","volume":"6","author":"Noordmans","year":"2001"},{"key":"b10","series-title":"Behav Brain Sci","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1017\/S0140525X00015491","article-title":"Brain organization for language from the perspective of electrical stimulation mapping.","volume":"6","author":"Ojemann","year":"1983"},{"key":"b11","series-title":"Neuroimage","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1006\/nimg.2000.0722","article-title":"Combined analysis of language tasks in fMRI improves assessment of hemispheric dominance for language functions in individual subjects.","volume":"13","author":"Ramsey","year":"2001"},{"key":"b12","series-title":"Neuroimage","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1006\/nimg.1998.0358","article-title":"Phase navigator correction in 3D fMRI improves detection of brain activation: quantitative assessment with a graded motor activation procedure.","volume":"8","author":"Ramsey","year":"1998"},{"key":"b13","series-title":"Surgical Treatment of the Epilepsies","first-page":"341","article-title":"Intra-arterial amobarbital procedures","author":"Rausch","year":"1993"},{"key":"b14","series-title":"Brain","doi-asserted-by":"publisher","first-page":"1683","DOI":"10.1093\/brain\/124.9.1683","article-title":"Presurgical evaluation of epilepsy.","volume":"124","author":"Rosenow","year":"2001"},{"key":"b15","series-title":"Neuroimage","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1006\/nimg.2002.1196","article-title":"fMRI-determined language lateralization in patients with unilateral or mixed language dominance according to the Wada test.","volume":"17","author":"Rutten","year":"2002"},{"key":"b16","series-title":"Ann Neurol","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1002\/ana.10117","article-title":"Development of a functional magnetic resonance imaging protocol for intraoperative localization of critical temporoparietal language areas.","volume":"51","author":"Rutten","year":"2002"},{"key":"b17","series-title":"J Exp Psychol [Hum Learn]","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1037\/0278-7393.6.2.174","article-title":"A standardized set of 260 pictures: norms for name agreement, image agreement, familiarity, and visual complexity.","volume":"6","author":"Snodgrass","year":"1980"},{"key":"b18","series-title":"Brain","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1093\/brain\/122.5.839","article-title":"Electrophysiological manifestations of open-and closed-class words in patients with Broca's aphasia with agrammatic comprehension. An event-related brain potential study.","volume":"122","author":"ter Keurs","year":"1999"},{"key":"b19","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"266","DOI":"10.3171\/jns.1960.17.2.0266","article-title":"Intracarotid injection of sodium amytal for the lateralization of cerebral speech dominance. Experimental and clinical observations.","volume":"17","author":"Wada","year":"1960"},{"key":"b20","series-title":"Epilepsia","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1111\/j.1528-1167.1990.tb06300.x","article-title":"Intracarotid amobarbital (Wada) test for language dominance: correlation with results of cortical stimulation.","volume":"31","author":"Wyllie","year":"1990"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/102\/1\/article-p169.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/102\/1\/article-p169.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/102\/1\/article-p169.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,3]],"date-time":"2022-07-03T15:19:41Z","timestamp":1656861581000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/102\/1\/article-p169.xml"}},"subtitle":["Case Report"],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":20,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.3171\/jns.2005.102.1.0169","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[2005,1]]}}}