{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:31:40Z","timestamp":1790742700276,"version":"4.1.0"},"reference-count":11,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,2]]},"abstract":"Object.<\/jats:italic> A grading system, called the Clinical\u2014Radiological Grading System (CRGS), has been developed to standardize surgical indications in elderly patients harboring intracranial meningiomas. Patients with a score lower than 10 had a bad prognosis regardless of surgical treatment, those with a score between 10 and 12 had a prognosis positively influenced by surgery, and those with a score higher than 12 had a good prognosis regardless of surgical treatment. The authors performed a prospective cross-sectional study to validate further the use of the CRGS as a clinical tool to orientate surgical decision making in elderly patients and to explore prognostic factors of survival.<\/jats:p>\nMethods.<\/jats:italic> From 1990 to 2000 the authors consecutively recruited and surgically treated 90 patients 70 years of age or older with neuroimaging findings of intracranial meningiomas and a preoperative evaluation based on the CRGS.<\/jats:p>\nThe surgical mortality rate, which covers deaths within 3 months after surgical intervention, was 7.8%, and the 1-year mortality rate was 15.6%.<\/jats:p>\nFemale sex and a higher CRGS score were associated with a higher probability of survival. Among the different subset items of the CRGS score, no peritumoral edema for surgical survival and no concomitant diseases for 1-year survival provide the strongest predictive contribution, even if not at a statistically significant level.<\/jats:p>\nConclusions.<\/jats:italic> The CRGS score is a useful and practical tool for the selection of elderly patients affected by intracranial meningiomas as surgical candidates. A CRGS score higher than 10 and female sex are good prognostic factors of survival, whereas age is not a contraindication to surgery.<\/jats:p>","DOI":"10.3171\/jns.2005.102.2.0290","type":"journal-article","created":{"date-parts":[[2009,5,13]],"date-time":"2009-05-13T18:11:07Z","timestamp":1242238267000},"page":"290-294","source":"Crossref","is-referenced-by-count":69,"title":["Surgery for intracranial meningiomas in the elderly: a clinical\u2014radiological grading system as a predictor of outcome"],"prefix":"10.3171","volume":"102","author":[{"given":"Manuela","family":"Caroli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Locatelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Prada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Beretta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Martinelli-Boneschi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolando","family":"Campanella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesare","family":"Arienta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01402612"},{"key":"b2","doi-asserted-by":"publisher","DOI":"10.1007\/s007010050209"},{"key":"b3","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1007\/BF01405421","volume":"102","author":"Cornu P","year":"1990","journal-title":"Acta Neurochir"},{"key":"b4","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(194811)1:4<634::AID-CNCR2820010410>3.0.CO;2-L"},{"key":"b5","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-199502000-00005"},{"key":"b6","doi-asserted-by":"publisher","DOI":"10.3109\/02688699209002915"},{"key":"b7","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/0090-3019(94)90241-0","volume":"42","author":"McGrail KM","year":"1994","journal-title":"Surg Neurol"},{"key":"b8","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1989.71.5.0665"},{"key":"b9","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/S0039-6109(16)43141-5","volume":"63","author":"Schneider AJL","year":"1983","journal-title":"Surg Clin North Am"},{"key":"b10","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1136\/jnnp.55.6.481","volume":"55","author":"Umansky F","year":"1992","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"b11","first-page":"24","volume-title":"Practical Geriatric Medicine","author":"Wekseler ME","year":"1985"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/102\/2\/article-p290.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/102\/2\/article-p290.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/102\/2\/article-p290.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,21]],"date-time":"2022-05-21T02:30:49Z","timestamp":1653100249000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/102\/2\/article-p290.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2]]},"references-count":11,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.3171\/jns.2005.102.2.0290","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[2005,2]]}}}