{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T10:27:37Z","timestamp":1781951257873,"version":"3.54.5"},"reference-count":13,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,6]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 Ancient change in a schwannoma is a histological variant typically found in longstanding tumors. Histologically, the tumor has biphasic features typical of a schwannoma with evidence of degenerative changes that may complicate diagnosis. The authors report on a 23-year-old man with no features of neurofibromatosis who presented with headaches, blurred vision, and ataxic gait. Magnetic resonance imaging demonstrated a rim-enhancing lesion in the cerebellopontine angle with displacement of brainstem structures and no supratentorial hydrocephalus. Using a lateral suboccipital approach together with image guidance and intraoperative neurophysiological monitoring, a gross-total macroscopic excision was performed. At surgery, the tumor was found to arise from the inferior division of the trigeminal nerve. The final histological diagnosis was schwannoma with ancient change. Note that ancient change in schwannomas is a histological variant thought to result from degenerative changes in longstanding tumors. To the authors' knowledge, this is the first independent report of this histological variant in an intracranial schwannoma.<\/jats:p>","DOI":"10.3171\/jns.2005.102.6.1163","type":"journal-article","created":{"date-parts":[[2009,5,13]],"date-time":"2009-05-13T18:04:03Z","timestamp":1242237843000},"page":"1163-1165","source":"Crossref","is-referenced-by-count":10,"title":["Trigeminal nerve schwannoma with ancient change"],"prefix":"10.3171","volume":"102","author":[{"given":"Kene","family":"Ugokwe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narendra","family":"Nathoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Prayson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gene H.","family":"Barnett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Cancer","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1002\/1097-0142(195107)4:4<669::AID-CNCR2820040405>3.0.CO;2-B","article-title":"Neurogenous tumors within the thorax: a clinicopathological evaluation of forty-eight cases.","volume":"4","author":"Ackerman","year":"1951"},{"key":"b2","series-title":"Ear Nose Throat J","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1177\/014556139607501209","article-title":"Ancient schwannoma of the submandibular gland: a case report.","volume":"75","author":"Bondy","year":"1996"},{"key":"b3","series-title":"Acta Pathol Microbiol Scand","first-page":"812","article-title":"Ancient neurilemmoma (schwannoma):","volume":"85","author":"Dahl","year":"1977"},{"key":"b4","series-title":"J Clin Neurosci","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1054\/jocn.2001.0952","article-title":"Intramedullary ancient schwannoma of the cervical spinal cord: case report and review of the literature.","volume":"9","author":"Darwish","year":"2002"},{"key":"b5","series-title":"J Craniomaxillofac Surg","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/S1010-5182(89)80097-6","article-title":"Ancient neurilemmoma (schwannoma) of the oral cavity.","volume":"17","author":"Dayan","year":"1989"},{"key":"b6","series-title":"J Otolaryngol","doi-asserted-by":"publisher","first-page":"236","DOI":"10.2310\/7070.2002.21156","article-title":"Ancient schwannoma of the infratemporal fossa.","volume":"31","author":"Huang","year":"2002"},{"key":"b7","series-title":"Arch Ophthalmol","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1001\/archopht.117.2.262","article-title":"Ancient schwannoma of the orbit.","volume":"117","author":"Khwarg","year":"1999"},{"key":"b8","series-title":"Folia Neuropathol","first-page":"237","article-title":"Correlation of facial nerve paresis and histopathological type of vestibular schwannoma.","volume":"41","author":"Kwiek","year":"2003"},{"key":"b9","series-title":"J Oral Surg","first-page":"731","article-title":"Ancient neurilemoma of the floor of the mouth: report of a case.","volume":"34","author":"Marks","year":"1976"},{"key":"b10","series-title":"Br J Neurosurg","doi-asserted-by":"publisher","first-page":"557","DOI":"10.3109\/02688699308995079","article-title":"Spinal subarachnoid haemorrhage from an \u201cancient\u201d schwannoma of the cervical spine.","volume":"7","author":"Mills","year":"1993"},{"key":"b11","series-title":"Jpn J Clin Oncol","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1093\/oxfordjournals.jjco.a023205","article-title":"Ancient schwannoma of the oral floor and ventricular portion of the tongue: a case report and review of the literature.","volume":"26","author":"Nakayama","year":"1996"},{"key":"b12","series-title":"Head Neck","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1002\/hed.2880130315","article-title":"Ancient neurilemmoma of the infratemporal fossa: a case report.","volume":"13","author":"Ogren","year":"1991"},{"key":"b13","series-title":"Am J Otolaryngol","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/S0196-0709(00)80127-1","article-title":"Ancient cervical vagal neurilemmoma: a case report.","volume":"21","author":"Saydam","year":"2000"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/102\/6\/article-p1163.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/102\/6\/article-p1163.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/102\/6\/article-p1163.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,3]],"date-time":"2022-07-03T15:07:13Z","timestamp":1656860833000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/102\/6\/article-p1163.xml"}},"subtitle":["Case report and review of the literature"],"short-title":[],"issued":{"date-parts":[[2005,6]]},"references-count":13,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.3171\/jns.2005.102.6.1163","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[2005,6]]}}}