{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T13:16:35Z","timestamp":1769346995616,"version":"3.49.0"},"reference-count":23,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,1]]},"abstract":"<jats:p content-type=\"fine-print\"><jats:italic>Object.<\/jats:italic> The authors evaluated the long-term efficacy of gamma knife surgery (GKS) in patients with trigeminal schwannomas.<\/jats:p>\n<jats:p content-type=\"fine-print\"><jats:italic>Methods.<\/jats:italic> Fifty-six patients, 31 women and 25 men (mean age 42 years), underwent GKS for trigeminal schwannomas. Fourteen had previously undergone surgery, and GKS was the primary treatment in the remaining 42 patients. The mean target volume was 8.7 cm<jats:sup>3<\/jats:sup> (range 0.8\u201333 cm<jats:sup>3<\/jats:sup>); the mean maximum dose was 27 Gy (range 20\u201340 Gy); the mean tumor margin dose was 13.3 Gy (range 10\u201315 Gy); and the mean follow-up period was 68 months (range 27\u2013114 months).<\/jats:p>\n<jats:p content-type=\"fine-print\">Disappearance of the tumor occurred in seven patients. An obvious decrease in tumor volume was observed in 41 patients, four tumors remained unchanged, and four tumors progressed at 5, 26, 30, and 60 months, respectively. One patient with disease progression died of tumor progression at 36 months after GKS. The tumor growth control rate in this group was 93% (52 of 56 cases).<\/jats:p>\n<jats:p content-type=\"fine-print\">Mild numbness or diplopia was relieved completely in 14 patients. Improvement of other neurological deficits was demonstrated in 25 patients. Trigeminal nerve dysfunction was either unchanged or slightly worse in 13 patients after GKS. Four patients experienced mild symptom deterioration related to tumor progression.<\/jats:p>\n<jats:p content-type=\"fine-print\"><jats:italic>Conclusions.<\/jats:italic> Radiosurgery proved to be an effective treatment for small- and medium-sized trigeminal schwannomas. Some larger tumors are also suitable for radiosurgery if there is no significant brainstem compression.<\/jats:p>","DOI":"10.3171\/jns.2005.102.s_supplement.0220","type":"journal-article","created":{"date-parts":[[2009,5,13]],"date-time":"2009-05-13T18:11:12Z","timestamp":1242238272000},"page":"220-224","source":"Crossref","is-referenced-by-count":23,"title":["Long-term results of Leksell gamma knife surgery for trigeminal schwannomas"],"prefix":"10.3171","volume":"102","author":[{"given":"Li","family":"Pan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"En-Min","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang-Fu","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bing-Jiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ya-Fei","family":"Dong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia-Zhong","family":"Dai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pei-Wu","family":"Cai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2002.96.3.0453"},{"key":"b2","doi-asserted-by":"publisher","DOI":"10.3109\/00016488109138503"},{"key":"b3","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-199802000-00015"},{"key":"b4","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-199905000-00008"},{"key":"b5","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2001.94.1.0001"},{"key":"b6","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-199907000-00002"},{"key":"b7","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(02)03651-9"},{"key":"b8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199811123392003"},{"key":"b9","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1007\/BF01412304","volume":"138","author":"Konovalov AN","year":"1996","journal-title":"Acta Neurochir (Wien)"},{"key":"b10","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/S0360-3016(98)00445-3","volume":"43","author":"Mabanta SR","year":"1999","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"b11","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1988.69.6.0850"},{"key":"b12","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0360-3016(98)00397-6","volume":"43","author":"Miller RC","year":"1999","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"b13","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-200112000-00003"},{"key":"b14","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1989.70.5.0737"},{"key":"b15","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1016\/S0360-3016(01)02711-0","volume":"52","author":"Pollock BE","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"b16","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-199809000-00041"},{"key":"b17","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2000.92.5.0745"},{"key":"b18","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1995.82.5.0711"},{"key":"b19","first-page":"437","volume":"50","author":"Sarma S","year":"2002","journal-title":"Neurosurgery"},{"key":"b20","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1995.82.5.0719"},{"key":"b21","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1989.71.4.0506"},{"key":"b22","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1999.91.2.0202"},{"key":"b23","first-page":"269","volume":"112","author":"Zhou L","year":"1999","journal-title":"Chin Med J (English)"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/102\/11806\/article-p220.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/thejns.org\/doi\/pdf\/10.3171\/jns.2005.102.s_supplement.0220","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,12]],"date-time":"2018-10-12T15:57:51Z","timestamp":1539359871000},"score":1,"resource":{"primary":{"URL":"http:\/\/thejns.org\/doi\/10.3171\/sup.2005.102.s_supplement.0220"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":23,"URL":"https:\/\/doi.org\/10.3171\/jns.2005.102.s_supplement.0220","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[2005,1]]}}}