{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T20:10:38Z","timestamp":1770149438948,"version":"3.49.0"},"reference-count":6,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,11]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713 The authors report on the case of a 14-year-old boy who presented with bilateral visual impairment due to optic canal stenosis caused by hyperplasia of the bone marrow arising from anemia. The patient had hereditary hemolytic anemia with unstable hemoglobin of the Christchurch type. This congenital form of anemia caused hyperplasia of the bone marrow as well as hyperostosis of the entire calvarial bone, which in turn led to optic canal stenosis. The patient underwent surgical decompression of the optic canal, resulting in significant improvement in visual acuity. Pathological findings in the calvarial bone indicated hypertrophic bone marrow with no other specific features such as neoplastic pattern or fibrous dysplasia. With the exception of objective hearing impairment, no other significant cranial neuropathy has been detected thus far.<\/jats:p>\n<jats:p content-type=\"fine-print\">On reviewing the published literature, this case was found to be the first in which hyperostosis due to congenital anemia resulted in symptomatic entrapment neuropathy of the optic nerve. The authors concluded that surgical decompression effectively improves visual acuity.<\/jats:p>","DOI":"10.3171\/jns.2005.103.5.0917","type":"journal-article","created":{"date-parts":[[2009,5,13]],"date-time":"2009-05-13T18:03:20Z","timestamp":1242237800000},"page":"917-919","source":"Crossref","is-referenced-by-count":6,"title":["Entrapment neuropathy of the optic nerve due to hyperostosis associated with congenital anemia"],"prefix":"10.3171","volume":"103","author":[{"given":"Takeo","family":"Baba","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiro","family":"Minamida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Mikami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Izumi","family":"Koyanagi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyohiro","family":"Houkin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Ann Anat","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/S0940-9602(04)80035-9","article-title":"Cribra orbitalia visualized in computed tomography.","volume":"186","author":"Exner","year":"2004"},{"key":"b2","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"1145","DOI":"10.1097\/00006123-199805000-00114","article-title":"Disease of skull in pre-Columbian South American mummies.","volume":"42","author":"Gerszten","year":"1998"},{"key":"b3","series-title":"Am J Hum Biol","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1002\/ajhb.1115","article-title":"Porotic hyperostosis as a marker of health and nutritional conditions during childhood: studies at the transition between Imperial Rome and the Early Middle Ages.","volume":"13","author":"Salvadei","year":"2001"},{"key":"b4","series-title":"J Clin Neurosci","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1054\/jocn.2002.1056","article-title":"Symptomatic cranial fibrous dysplasias: clinico-radiological analysis in a series of eight operative cases with follow-up results.","volume":"9","author":"Sharma","year":"2002"},{"key":"b5","series-title":"Am J Phys Anthropol","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1002\/ajpa.1330740410","article-title":"Porotic hyperostosis: new evidence to support the anemia theory.","volume":"74","author":"Stuart-Macadam","year":"1987"},{"key":"b6","series-title":"Am J Phys Anthropol","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1002\/ajpa.10321","article-title":"Is cribra orbitalia synonymous with anemia? Analysis and interpretation of cranial pathology in Sudan.","volume":"123","author":"Wapler","year":"2004"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/103\/5\/article-p917.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/103\/5\/article-p917.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/103\/5\/article-p917.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,3]],"date-time":"2022-07-03T17:06:05Z","timestamp":1656867965000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/103\/5\/article-p917.xml"}},"subtitle":["Case report"],"short-title":[],"issued":{"date-parts":[[2005,11]]},"references-count":6,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.3171\/jns.2005.103.5.0917","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[2005,11]]}}}