{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T15:53:22Z","timestamp":1790178802600,"version":"4.1.0"},"reference-count":34,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2006,3]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>The extent of peritumoral brain edema (PTBE) associated with meningiomas can be highly variable. The authors studied the correlation between the development of efferent venous drainage from the tumor and the degree of PTBE that occurs in intracranial meningiomas.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>Twenty-five patients with 27 intracranial supratentorial meningiomas were investigated to identify the correlation between the efferent venous drainage system of the tumor and peritumoral edema. The overall mean age of the patients was 54 years. Seventeen patients (68%) were female and eight (32%) were male. All patients underwent magnetic resonance imaging and digital subtraction angiography. In each meningioma, superselective angiography of the dominant feeding artery was performed, including the late venous phase to evaluate the development of the tumor\u2019s draining vein. An edema index (EI) was introduced to serve as an objective means by which to judge the extent of PTBE. Eleven meningiomas (41%), in which the mean EI was 0.14 \u00b1 0.10, clearly showed dominant draining veins originating from the tumor itself. In the other 16 meningiomas (59%), superselective angiography demonstrated no efferent venous drainage from the tumor, which could account for this group\u2019s mean EI value of 1.49 \u00b1 1.05 (p &lt; 0.001)<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>The current results suggest that hypoplasia of the efferent draining vein from the meningioma itself contributes to PTBE formation. The development of an efferent venous system mitigates against the formation of PTBE. Intratumoral venous congestion can be considered the main cause of PTBE in meningiomas.<\/jats:p><\/jats:sec>","DOI":"10.3171\/jns.2006.104.3.382","type":"journal-article","created":{"date-parts":[[2008,1,24]],"date-time":"2008-01-24T12:30:53Z","timestamp":1201177853000},"page":"382-388","source":"Crossref","is-referenced-by-count":49,"title":["Correlation between the efferent venous drainage of the tumor and peritumoral edema in intracranial meningiomas: superselective angiographic analysis of 25 cases"],"prefix":"10.3171","volume":"104","author":[{"given":"Michihiro","family":"Tanaka","sequence":"first","affiliation":[{"name":"Institute of Neuroradiology and Department of Neurosurgery, University Hospital Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans G.","family":"Imhof","sequence":"additional","affiliation":[{"name":"Institute of Neuroradiology and Department of Neurosurgery, University Hospital Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Schucknecht","sequence":"additional","affiliation":[{"name":"Institute of Neuroradiology and Department of Neurosurgery, University Hospital Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Spyros","family":"Kollias","sequence":"additional","affiliation":[{"name":"Institute of Neuroradiology and Department of Neurosurgery, University Hospital Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Yonekawa","sequence":"additional","affiliation":[{"name":"Institute of Neuroradiology and Department of Neurosurgery, University Hospital Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anton","family":"Valavanis","sequence":"additional","affiliation":[{"name":"Institute of Neuroradiology and Department of Neurosurgery, University Hospital Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-1040382","series-title":"Surg Neurol","first-page":"471","article-title":"Cerebral edema in intracranial meningiomas: evidence for local and diffuse patterns and factors associated with its occurrence","volume":"43","year":"1994"},{"key":"b2-1040382","series-title":"Neurochirurgie","first-page":"337","article-title":"Facteurs prognostiques dans la chirurgie des m\u00e9ningiomes intr\u00e2craniens. 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