{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:00:31Z","timestamp":1790690431685,"version":"4.1.0"},"reference-count":32,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2006,8]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>The aim of this study was to assess the consequences of total removal of a large vestibular schwannoma on the patient\u2019s symptoms and quality of life (QOL).<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>A questionnaire regarding preoperative and postoperative symptoms with measures of both daily and global QOL and a modified 36-Item Short Form Health Survey (SF-36) QOL instrument were sent to 103 patients who had undergone surgery via a retrosigmoid approach for total removal of a Grade III or IV vestibular schwannoma. In addition, 48 patients underwent follow-up clinical examinations to assess their conditions.<\/jats:p>\n<jats:p>Seventy-two of the 103 patients completed and returned the questionnaire. Forty-six (64%) of the schwannomas were Grade IV and 26 (36%) were Grade III. The patients\u2019 pre- and postoperative symptoms were similar to those reported in other studies. The patients\u2019 perceptions of facial movement were likely to be worse than the clinicians\u2019 estimation based on the House\u2013Brackmann classification. All scores in the QOL categories were significantly reduced when compared with normative data. Patients with large vestibular schwannomas had lower scores in all SF-36 categories except pain compared with data from other studies. Psychological problems were the preponderant symptoms, and their presence was the most powerful predictive variable for global and daily QOL.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Surgery for a large vestibular schwannoma has a significant impact on the patient\u2019s QOL. To improve QOL postoperatively, the patient should be prepared and well informed of the consequences of such a surgery on QOL. Clinicians must be aware that early involvement of a clinical psychologist may be very helpful.<\/jats:p><\/jats:sec>","DOI":"10.3171\/jns.2006.105.2.205","type":"journal-article","created":{"date-parts":[[2008,1,24]],"date-time":"2008-01-24T12:37:17Z","timestamp":1201178237000},"page":"205-212","source":"Crossref","is-referenced-by-count":74,"title":["Surgery for large vestibular schwannomas: how patients and surgeons perceive quality of life"],"prefix":"10.3171","volume":"105","author":[{"given":"Keyvan","family":"Nicoucar","sequence":"first","affiliation":[{"name":"Division of Otolaryngology, Head and Neck Surgery, and Division of Neurosurgery, University Hospital of Geneva; and Institute of Social and Preventive Medicine\u2013Health Care Evaluation Unit, University of Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahan","family":"Momjian","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology, Head and Neck Surgery, and 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