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Using the reported sensitivities and specificities of several such tests, they evaluated the effects such tests would have on the expected outcome of an average 65-year-old patient with moderate dementia. They also evaluated the cost-effectiveness of a theoretical screening test with superior sensitivity and specificity.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Although external lumbar drainage comes quite close, none of the screening tests reported to date have sufficient sensitivity and specificity to improve expected outcome in an average candidate, compared with the results of automatic shunt placement in cases of suspected NPH. In addition, even a theoretically improved test would need to be considerably less expensive than prolonged lumbar drainage to be cost-effective in clinical practice.<\/jats:p><\/jats:sec>","DOI":"10.3171\/jns.2006.105.6.823","type":"journal-article","created":{"date-parts":[[2008,1,24]],"date-time":"2008-01-24T12:41:37Z","timestamp":1201178497000},"page":"823-829","source":"Crossref","is-referenced-by-count":19,"title":["Screening tests for normal-pressure hydrocephalus: sensitivity, specificity, and cost"],"prefix":"10.3171","volume":"105","author":[{"given":"Mark G.","family":"Burnett","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery and Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seema S.","family":"Sonnad","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and Surgery, Hospital of the University of Pennsylvania, Philadelphia, 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