{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T21:50:35Z","timestamp":1779918635307,"version":"3.53.1"},"reference-count":27,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:p>\u2713 The authors report the unusual case of a 35-year-old woman suffering from left leg numbness and radiculopathy due to multiple lesions in the central nervous system: one right parietal extracranial\u2013intracranial lesion with invasion of the sensory cortex, and two intraspinal, intradural lesions compressing the spinal cord at T3\u20135 and S1\u20134. Biopsy sampling of the extracranial part of the parietal lesion led to a diagnosis of myeloid sarcoma. Further examination revealed no evidence of leukemic disease or myeloproliferative disorder. An aggressive multimodal approach to treatment in this patient with a combination of chemotherapy, whole-body radiotherapy, and allogeneic bone marrow transplantation was started immediately. The patient experienced full neurological recovery and complete disappearance of all lesions. At the 7-year follow-up examination, there was no evidence of disease. To the authors\u2019 knowledge, this is the first report of a myeloid sarcoma with both intracranial and intraspinal manifestations in a patient without leukemia.<\/jats:p>","DOI":"10.3171\/jns.2006.105.6.916","type":"journal-article","created":{"date-parts":[[2008,1,24]],"date-time":"2008-01-24T12:41:37Z","timestamp":1201178497000},"page":"916-919","source":"Crossref","is-referenced-by-count":38,"title":["Myeloid sarcoma with multiple lesions of the central nervous system in a patient without leukemia"],"prefix":"10.3171","volume":"105","author":[{"given":"Georg","family":"Widhalm","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery, Clinical Pathology, and Internal Medicine, Medical University of Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Dietrich","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery, Clinical Pathology, and Internal Medicine, Medical University of Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonhard","family":"M\u00fcllauer","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery, Clinical Pathology, and Internal Medicine, Medical University of Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berthold","family":"Streubel","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery, Clinical Pathology, and Internal Medicine, Medical University of Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Werner","family":"Rabitsch","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery, Clinical Pathology, and Internal Medicine, Medical University of Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark R.","family":"Kotter","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery, Clinical Pathology, and Internal Medicine, Medical University of Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Engelbert","family":"Knosp","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery, Clinical Pathology, and Internal Medicine, Medical University of Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl","family":"Roessler","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery, Clinical Pathology, and Internal Medicine, Medical University of Vienna, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-1050916","series-title":"J Clin Pathol","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1136\/jcp.52.9.705","article-title":"Granulocytic sarcoma preceding AML M0 and the diagnostic value of CD34","volume":"52","year":"1999"},{"key":"b2-1050916","series-title":"Arch Pathol Lab Med","first-page":"203","article-title":"Pathogenesis of central nervous system infiltration in acute leukemia","volume":"101","year":"1977"},{"key":"b3-1050916","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1148\/radiology.160.1.3459211","article-title":"Granulocytic sarcoma of the brain: a case report and review of the literature","volume":"160","year":"1986"},{"key":"b4-1050916","series-title":"Ann Hematol","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1007\/s002770000165","article-title":"Isolated meningeal chloroma (granulocytic sarcoma)\u2014a case report and review of the literature","volume":"79","year":"2000"},{"key":"b5-1050916","series-title":"Leuk Res","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1016\/j.leukres.2004.01.022","article-title":"Clinicopathological characteristics of myeloid sarcoma at diagnosis and during follow-up: report of 12 cases from a single institution","volume":"28","year":"2004"},{"key":"b6-1050916","series-title":"Observations on the Surgical Anatomy of the Head and Neck. 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