{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T07:21:42Z","timestamp":1769498502281,"version":"3.49.0"},"reference-count":15,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2007,2]]},"abstract":"\nObject<\/jats:title>\nThe HydroCoil embolization system is a helical platinum coil coated with a polymeric hydrogel that expands when it contacts aqueous solutions to increase filling volumes, improve mesh stability, and possibly elicit a healing response within the aneurysm. In this paper, the authors report the 1-year recurrence and complication rates of 67 aneurysms embolized with the HydroCoil system.<\/jats:p><\/jats:sec>\n\nMethods<\/jats:title>\nSixty-four consecutive patients (67 total aneurysms) with small (\u2264 7 mm), large (8\u201315 mm), very large (16\u201324 mm), and giant (\u2265 25 mm) aneurysms in the anterior and posterior intracranial circulations were treated with HydroCoils between March 2003 and September 2004. All aneurysms were embolized by the senior author (A.S.B) with HydroCoils alone or in combination with bare platinum coils, until either there was no further angiographic contrast filling of the aneurysm or the microcatheter was pushed out of the dome by the coil mass. Balloon assistance was used in three cases and combined Neuroform stent\u2013coil embolization in eight other cases. To evaluate the safety and 1-year efficacy of the HydroCoil system, periprocedural complications were recorded, and angiographic recurrences were categorized using the Raymond\u2013Roy Occlusion Classification (RROC) system.<\/jats:p>\nThe 1-year aneurysm recurrence rate independent of size was 15% in patients treated with HydroCoils. Seventy percent of the patients had stable occlusions. The recurrence rate for small aneurysms was 3.7%, and the combined recurrence rate for small and large aneurysms was 6%. Fifteen percent of the aneurysms initially categorized as RROC Type 2 or 3 with stasis of contrast material at the time of initial embolization improved in RROC type, allowing the authors to develop the aneurysm embolization grade to predict recurrence. The neurological complication rate was 14.9%, of which 4.5% represented permanent neurological deficits.<\/jats:p><\/jats:sec>\n\nConclusions<\/jats:title>\nThe HydroCoil embolization system is safe and provides excellent 1-year occlusion of small and large aneurysms with initial RROC Type 1, as well as those with RROC Types 2 and 3 with stasis of contrast material at the time of embolization. Very large and giant aneurysms were not as successfully occluded with this system. Treatment of large and giant internal carotid artery aneurysms was more likely to result in cranial nerve palsies and postembolization headaches than treatment in other locations. The aneurysm embolization grade the authors developed using the results of this study accurately predicted 1-year recurrence rates based on the immediate postembolization angiographic characteristics of the treated aneurysm.<\/jats:p><\/jats:sec>","DOI":"10.3171\/jns.2007.106.2.226","type":"journal-article","created":{"date-parts":[[2008,1,24]],"date-time":"2008-01-24T12:44:23Z","timestamp":1201178663000},"page":"226-233","source":"Crossref","is-referenced-by-count":54,"title":["A prospective single-center analysis of the safety and efficacy of the HydroCoil embolization system for the treatment of intracranial aneurysms"],"prefix":"10.3171","volume":"106","author":[{"given":"Eric M.","family":"Deshaies","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew A.","family":"Adamo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan S.","family":"Boulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"2","key":"b1-1060226","series-title":"Neurosurg Focus","first-page":"E1","article-title":"Hydrogel-coated coils for the treatment of cerebral aneurysms: preliminary results","volume":"18","year":"2005"},{"key":"b2-1060226","series-title":"AJNR Am J Neuroradiol","first-page":"904","article-title":"Changes in the intraaneurysmal pressure due to HydroCoil embolization","volume":"26","year":"2005"},{"key":"b3-1060226","series-title":"AJNR Am J Neuroradiol","first-page":"60","article-title":"Aneurysm packing with HydroCoil Embolic System versus platinum coils: initial clinical experience","volume":"25","year":"2004"},{"issue":"2","key":"b4-1060226","series-title":"Neurosurg Focus","first-page":"E5","article-title":"Determination of filling volumes in HydroCoil-treated aneurysms by using three-dimensional computerized tomography 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