{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T23:13:59Z","timestamp":1725578039321},"reference-count":60,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2007,4]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>The goal in this article was to compare 0.1 mmol\/kg doses of gadobenate dimeglumine (Gd-BOPTA) and gadopentetate dimeglumine, also known as gadolinium diethylenetriamine pentaacetic acid (Gd-DTPA), for enhanced magnetic resonance (MR) imaging of intraaxial brain tumors.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>Eighty-four patients with either intraaxial glioma (47 patients) or metastasis (37 patients) underwent two MR imaging examinations at 1.5 tesla, one with Gd-BOPTA as the contrast agent and the other with Gd-DTPA. The interval between fully randomized contrast medium administrations was 2 to 7 days. The T<jats:sub>1<\/jats:sub>-weighted spin echo and T<jats:sub>2<\/jats:sub>-weighted fast spin echo images were acquired before administration of contrast agents and T<jats:sub>1<\/jats:sub>-weighted spin echo images were obtained after the agents were administered. Acquisition parameters and postinjection acquisition times were identical for the two examinations in each patient. Three experienced readers working in a fully blinded fashion independently evaluated all images for degree and quality of available information (lesion contrast enhancement, lesion border delineation, definition of disease extent, visualization of the lesion's internal structures, global diagnostic preference) and quantitative enhancement (that is, the extent of lesion enhancement after contrast agent administration compared with that seen before its administration [hereafter referred to as percent enhancement], lesion\/brain ratio, and contrast\/noise ratio). Differences were tested with the Wilcoxon signed-rank test. Reader agreement was assessed using kappa statistics.<\/jats:p>\n<jats:p>Significantly better diagnostic information\/imaging performance (p &lt; 0.0001, all readers) was obtained with Gd-BOPTA for all visualization end points. Global preference for images obtained with Gd-BOPTA was expressed for 42 (50%), 52 (61.9%), and 56 (66.7%) of 84 patients (readers 1, 2, and 3, respectively) compared with images obtained with Gd-DTPA contrast in four (4.8%), six (7.1%), and three (3.6%) of 84 patients. Similar differences were noted for all other visualization end points. Significantly greater quantitative contrast enhancement (p &lt; 0.04) was noted after administration of Gd-BOPTA. Reader agreement was good (\u03ba &gt; 0.4).<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Lesion visualization, delineation, definition, and contrast enhancement are significantly better after administration of 0.1 mmol\/kg Gd-BOPTA, potentially allowing better surgical planning and follow up and improved disease management.<\/jats:p><\/jats:sec>","DOI":"10.3171\/jns.2007.106.4.557","type":"journal-article","created":{"date-parts":[[2008,1,24]],"date-time":"2008-01-24T12:50:27Z","timestamp":1201179027000},"page":"557-566","source":"Crossref","is-referenced-by-count":34,"title":["Evaluation of intraaxial enhancing brain tumors on magnetic resonance imaging: intraindividual crossover comparison of gadobenate dimeglumine and gadopentetate dimeglumine for visualization and assessment, and implications for surgical intervention"],"prefix":"10.3171","volume":"106","author":[{"given":"Matthew J.","family":"Kuhn","sequence":"first","affiliation":[{"name":"Department of Radiology, Southern Illinois University School of Medicine, Springfield, Illinois;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piero","family":"Picozzi","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph A.","family":"Maldjian","sequence":"additional","affiliation":[{"name":"Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilona M.","family":"Schmalfuss","sequence":"additional","affiliation":[{"name":"Neuroradiology Research, University of Florida, Gainesville, Florida;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth R.","family":"Maravilla","sequence":"additional","affiliation":[{"name":"Neuroradiology and MR Research Laboratory, University of Washington, Seattle, Washington;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian C.","family":"Bowen","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Miami School of Medicine, Miami, Florida;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franz J.","family":"Wippold","sequence":"additional","affiliation":[{"name":"Department of Radiology, Washington University, St. Louis, Missouri;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Val M.","family":"Runge","sequence":"additional","affiliation":[{"name":"Department of Radiology, Scott and White Memorial Hospital, Temple, Texas;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael V.","family":"Knopp","sequence":"additional","affiliation":[{"name":"Department of Radiology, The Ohio State University\u2014University Hospitals, Columbus, Ohio;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leo J.","family":"Wolansky","sequence":"additional","affiliation":[{"name":"Department of Radiology, University Hospital, Newark, New Jersey;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"Gustafsson","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Sahlgrenska University Hospital, G\u00f6teborg, Sweden; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Essig","sequence":"additional","affiliation":[{"name":"German Cancer Research Institute, Heidelberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicoletta","family":"Anzalone","sequence":"additional","affiliation":[{"name":"Neuroradiology, San Raffaele Hospital, Milan, Italy;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-1060557","series-title":"Neurosurgery","first-page":"45","article-title":"Early postoperative magnetic resonance imaging after resection of malignant glioma: objective evaluation of residual tumor and its influence on regrowth and prognosis","volume":"34","author":"Albert","year":"1994"},{"key":"b2-1060557","series-title":"Surg Neurol","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1016\/S0090-3019(01)00588-2","article-title":"Is intraoperative MR-guided surgery of value?","volume":"56","author":"Ausman","year":"2001"},{"key":"b3-1060557","series-title":"Nuclear and Electron Relaxation","first-page":"138","author":"Banci","year":"1991"},{"key":"b4-1060557","series-title":"Semin Oncol","first-page":"172","article-title":"Malignant astrocytomas: surgical aspects","volume":"21","author":"Berger","year":"1994"},{"key":"b5-1060557","series-title":"Invest Radiol","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1097\/00004424-199712000-00009","article-title":"Gadolinium chelates with weak binding to serum proteins. A new class of high-efficiency, general purpose contrast agents for magnetic resonance imaging","volume":"32","author":"Cavagna","year":"1997"},{"key":"b6-1060557","series-title":"Clin Neurosurg","first-page":"375","article-title":"Aggressive surgery for malignant supratentorial gliomas","volume":"36","author":"Ciric","year":"1990"},{"key":"b7-1060557","series-title":"Pediatr Radiol","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1007\/s00247-004-1392-4","article-title":"Comparison of gadobenate dimeglumine (Gd-BOPTA) with gadopentetate dimeglumine (Gd-DTPA) for enhanced MR imaging of brain and spine tumors in children","volume":"35","author":"Colosimo","year":"2005"},{"key":"b8-1060557","series-title":"Neuroradiology","first-page":"655","article-title":"A comparison of Gd-BOPTA and Gd-DOTA for contrast-enhanced MRI of intracranial tumors","volume":"46","author":"Colosimo","year":"2004"},{"key":"b9-1060557","series-title":"Nomenclature and Criteria for Diagnosis of Diseases of the Heart and Great Vessels","author":"Criteria Committee of the American Heart Association","year":"1994"},{"issue":"1 Suppl","key":"b10-1060557","series-title":"J Comput Assist Tomogr","doi-asserted-by":"publisher","first-page":"S161","DOI":"10.1097\/00004728-199911001-00021","article-title":"Gadobenate dimeglumine 0.5 M solution for injection (Multi-Hance) pharmaceutical formulation and physicochemical properties of a new magnetic resonance imaging contrast medium","volume":"23","author":"de Haen","year":"1999"},{"key":"b11-1060557","series-title":"J Magn Reson Imaging","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1002\/jmri.1880030130","article-title":"Soluble-type hepatobiliary contrast agents for MR imaging","volume":"3","author":"de Ha\u00ebn","year":"1993"},{"key":"b12-1060557","series-title":"Eur J Radiol","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/S0720-048X(02)00027-X","article-title":"Early-postoperative magnetic resonance imaging in glial tumors: prediction of tumor regrowth and recurrence","volume":"45","author":"Ekinci","year":"2003"},{"key":"b13-1060557","series-title":"Acad Radiol","doi-asserted-by":"publisher","first-page":"744","DOI":"10.1016\/j.acra.2006.02.056","article-title":"Enhancing lesions of the brain: intraindividual crossover comparison of contrast enhancement after gadobenate dimeglumine versus established gadolinium comparators","volume":"13","author":"Essig","year":"2006"},{"issue":"5 Suppl","key":"b14-1060557","series-title":"Neurosurgery","first-page":"S66","article-title":"Current treatment paradigms for the management of patients with brain metastases","volume":"57","author":"Ewend","year":"2005"},{"key":"b15-1060557","series-title":"The Design and Analysis of Clinical Experiments","first-page":"76","author":"Fleiss","year":"1999"},{"key":"b16-1060557","series-title":"Statistical Methods for Rates and Proportions","author":"Fleiss","year":"1981"},{"key":"b17-1060557","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"318","DOI":"10.3171\/jns.2005.102.2.0318","article-title":"Multimodal metabolic imaging of cerebral gliomas: positron emission tomography with [18F]fluoroethyl-L-tyrosine and magnetic resonance spectroscopy","volume":"102","author":"Floeth","year":"2005"},{"key":"b18-1060557","series-title":"Australas Radiol","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1046\/j.1440-1673.2001.00957.x","article-title":"Phase III, randomized, double-blind, cross-over comparison of gadoteridol and gadopentetate dimeglumine in magnetic resonance imaging of patients with intracranial lesions","volume":"45","author":"Greco","year":"2001"},{"key":"b19-1060557","series-title":"Invest Radiol","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1097\/00004424-200007000-00003","article-title":"Magnetic resonance imaging in patients with central nervous system pathology: a comparison of OptiMARK (Gd-DTPA-BMEA) and Magnevist (Gd-DTPA)","volume":"35","author":"Grossman","year":"2000"},{"key":"b20-1060557","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1148\/radiology.165.3.3317496","article-title":"Increased detection of intracranial metastases with intravenous Gd-DTPA","volume":"165","author":"Healy","year":"1987"},{"key":"b21-1060557","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1148\/radiology.170.1.2535765","article-title":"Human cerebral gliomas: correlation of postmortem MR imaging and neuropathologic findings","volume":"170","author":"Johnson","year":"1989"},{"key":"b22-1060557","series-title":"Neuroimaging Clin N Am","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1016\/S1052-5149(02)00036-9","article-title":"Intraoperative magnetic resonance imaging and magnetic resonance imaging-guided therapy for brain tumors","volume":"12","author":"Jolesz","year":"2002"},{"key":"b23-1060557","series-title":"Lancet Neurol","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/S1474-4422(05)70072-7","article-title":"Therapeutic management of brain metastasis","volume":"4","author":"Kaal","year":"2005"},{"key":"b24-1060557","series-title":"J Neurooncol","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1007\/s11060-004-8094-5","article-title":"Symptomatic management and imaging of brain metastases","volume":"75","author":"Kaal","year":"2005"},{"key":"b25-1060557","series-title":"J Magn Reson Imaging","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1002\/jmri.1184","article-title":"Safety assessment of gadobenate dimeglumine (Multihance): extended clinical experience from phase I studies to post-marketing surveillance","volume":"14","author":"Kirchin","year":"2001"},{"key":"b26-1060557","series-title":"Top Magn Reson Imaging","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1097\/00002142-200310000-00007","article-title":"Contrast agents for magnetic resonance imaging: safety update","volume":"14","author":"Kirchin","year":"2003"},{"key":"b27-1060557","series-title":"AJNR Am J Neuroradiol","first-page":"1642","article-title":"Intraoperative MR imaging increases the extent of tumor resection in patients with high-grade gliomas","volume":"20","author":"Knauth","year":"1999"},{"key":"b28-1060557","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1148\/radiology.211.3.r99jn46791","article-title":"Glial neoplasms: dynamic contrast-enhanced T2*-weighted MR imaging","volume":"211","author":"Knopp","year":"1999"},{"key":"b29-1060557","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1148\/radiol.2301021085","article-title":"Primary and secondary brain tumors at MR imaging: bicentric intraindividual crossover comparison of gadobenate dimeglumine and gadopentetate dimeglumine","volume":"230","author":"Knopp","year":"2004"},{"key":"b30-1060557","series-title":"Int J Radiat Oncol Biol Phys","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1016\/S0360-3016(99)00198-4","article-title":"Stereotactic radiosurgery plus whole brain radiotherapy versus radiotherapy alone for patients with multiple brain metastases","volume":"45","author":"Kondziolka","year":"1999"},{"key":"b31-1060557","series-title":"Top Magn Reson Imaging","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1097\/00002142-200410000-00003","article-title":"MR spectroscopy of brain tumors","volume":"15","author":"Law","year":"2004"},{"key":"b32-1060557","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"467","DOI":"10.3171\/jns.2003.99.3.0467","article-title":"Survival following surgery and prognostic factors for recently diagnosed malignant glioma: data from the Glioma Outcomes Project","volume":"99","author":"Laws","year":"2003"},{"key":"b33-1060557","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"642","DOI":"10.3171\/jns.1980.52.5.0642","article-title":"Prognostic significance of the pretreatment CT scan on time to progression for patients with malignant gliomas","volume":"52","author":"Levin","year":"1980"},{"key":"b34-1060557","series-title":"Magn Reson Imaging Clin N Am","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/S1064-9689(21)00447-5","article-title":"Contrast dosage in the neuroimaging of brain tumors. Principles and indications","volume":"6","author":"Maley","year":"1998"},{"key":"b35-1060557","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1148\/radiol.2402051266","article-title":"Contrast enhancement of central nervous system lesions: multicenter intraindividual crossover comparative study of two MR contrast agents","volume":"240","author":"Maravilla","year":"2006"},{"key":"b36-1060557","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1148\/radiology.215.1.r00ap31221","article-title":"Brain tumor resection: intraoperative monitoring with high-field-strength MR imaging\u2014initial results","volume":"215","author":"Martin","year":"2000"},{"issue":"5 Suppl","key":"b37-1060557","series-title":"Neurosurgery","first-page":"S45","article-title":"Radiosurgery in metastatic brain cancer","volume":"57","author":"McDermott","year":"2005"},{"key":"b38-1060557","series-title":"Acta Radiol","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1177\/028418519203300504","article-title":"Gadodiamide injection and gado-pentetate dimeglumine: a double-blind study in MR imaging of the CNS","volume":"33","author":"Myhr","year":"1992"},{"issue":"Suppl","key":"b39-1060557","series-title":"Acta Neurochir","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1007\/978-3-7091-6043-5_8","article-title":"Glioma surgery evaluated by intraoperative low-field magnetic resonance imaging","volume":"85","author":"Nimsky","year":"2003"},{"key":"b40-1060557","series-title":"Acad Radiol","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1016\/j.acra.2005.05.020","article-title":"Comparing 0.2 tesla with 1.5 tesla intraoperative magnetic resonance imaging analysis of setup, workflow, and efficiency","volume":"12","author":"Nimsky","year":"2005"},{"key":"b41-1060557","series-title":"Neurosurg Clin N Am","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/j.nec.2004.07.001","article-title":"1.5 T: intraoperative imaging beyond standard anatomic imaging","volume":"16","author":"Nimsky","year":"2005"},{"key":"b42-1060557","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1148\/radiol.2331031352","article-title":"Intraoperative high-field-strength MR imaging: implementation and experience in 200 patients","volume":"233","author":"Nimsky","year":"2004"},{"key":"b43-1060557","series-title":"Neurosurg Clin N Am","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.nec.2004.07.010","article-title":"A low-field intraoperative MRI system for glioma surgery: is it worthwhile?","volume":"16","author":"Oh","year":"2005"},{"key":"b44-1060557","series-title":"J Magn Reson Imaging","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1002\/jmri.20335","article-title":"Quantitative apparent diffusion coefficients and T2 relaxation times in characterizing contrast enhancing brain tumors and regions of peritumoral edema","volume":"21","author":"Oh","year":"2005"},{"key":"b45-1060557","series-title":"Invest Radiol","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1097\/00004424-199502000-00002","article-title":"Safety and efficacy of dotarem (Gd-DOTA) versus magnevist (Gd-DTPA) in magnetic resonance imaging of the central nervous system","volume":"30","author":"Oudkerk","year":"1995"},{"key":"b46-1060557","series-title":"Neurosurgery","first-page":"1021","article-title":"Reevaluation of surgery for the treatment of brain metastases: review of 208 patients with single or multiple brain metastases treated at one institution with modern neurosurgical techniques","volume":"56","author":"Paek","year":"2005"},{"key":"b47-1060557","series-title":"JAMA","first-page":"1485","article-title":"Postoperative radiotherapy in the treatment of single metastases to the brain: a randomized trial","volume":"280","author":"Patchell","year":"1998"},{"key":"b48-1060557","series-title":"Invest Radiol","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1097\/01.rli.0000197668.44926.f7","article-title":"Relaxivity of gadopentetate dimeglumine (Magnevist), gadobutrol (Gadovist), and gadobenate dimeglumine (Multi-Hance) in human blood plasma at 0.2, 1.5, and 3 Tesla","volume":"41","author":"Pintaske","year":"2006"},{"key":"b49-1060557","series-title":"Neuroradiology","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1007\/s00234-005-0030-7","article-title":"Clinical relevance of diffusion and perfusion magnetic resonance imaging in assessing intraaxial brain tumors","volume":"48","author":"Rollin","year":"2006"},{"key":"b50-1060557","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1227\/00006123-198101000-00004","article-title":"Value of sequential computed tomography in the multimodality treatment of glioblastoma multiforme","volume":"8","author":"Salcman","year":"1981"},{"key":"b51-1060557","series-title":"Neuroradiology","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1007\/s00234-005-0024-5","article-title":"Pattern of T2 hypointensity associated with ring-enhancing brain lesions can help to differentiate pathology","volume":"48","author":"Schwartz","year":"2006"},{"key":"b52-1060557","series-title":"Acta Neuropathol (Berl)","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1007\/BF00693780","article-title":"Immunohistochemical demonstration of serum proteins in human cerebral gliomas","volume":"73","author":"Seitz","year":"1987"},{"key":"b53-1060557","series-title":"Invest Radiol","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1097\/01.rli.0000209661.99225.c2","article-title":"Safety of gadobenate dimeglumine: summary of findings from clinical studies and post-marketing surveillance","volume":"41","author":"Shellock","year":"2006"},{"key":"b54-1060557","series-title":"Acad Radiol","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1016\/S1076-6332(99)80451-6","article-title":"Safety, tolerance, biodistribution, and MR imaging enhancement of the liver with gadobenate dimeglumine: results of clinical pharmacologic and pilot imaging studies in nonpatient and patient volunteers","volume":"6","author":"Spinazzi","year":"1999"},{"key":"b55-1060557","series-title":"Neuroradiology","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1007\/BF00588486","article-title":"A double-blind, comparative study of gadodiamide injection and gadopentetate dimeglumine in MRI of the central nervous system","volume":"35","author":"Valk","year":"1993"},{"issue":"Suppl","key":"b56-1060557","series-title":"Acta Neurochir","first-page":"13","article-title":"Postoperative imaging after brain tumor resection","volume":"88","author":"Warmuth-Metz","year":"2003"},{"key":"b57-1060557","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1148\/radiology.180.2.2068317","article-title":"MR evaluation of CNS tumors: dose comparison study with gadopentetate dimeglumine and gadoteridol","volume":"180","author":"Yuh","year":"1991"},{"key":"b58-1060557","series-title":"AJNR Am J Neuroradiol","first-page":"335","article-title":"Experience with high-dose gadolinium MR imaging in the evaluation of brain metastases","volume":"13","author":"Yuh","year":"1992"},{"key":"b59-1060557","series-title":"J Magn Reson Imaging","first-page":"242","article-title":"Dose of contrast material in the MR imaging evaluation of central nervous system tumors","volume":"4","author":"Yuh","year":"1994"},{"key":"b60-1060557","series-title":"AJNR Am J Neuroradiol","first-page":"373","article-title":"The effect of contrast dose, imaging time, and lesion size in the MR detection of intracerebral metastasis","volume":"16","author":"Yuh","year":"1995"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/106\/4\/article-p557.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/106\/4\/article-p557.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/106\/4\/article-p557.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,9]],"date-time":"2024-03-09T10:11:51Z","timestamp":1709979111000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/106\/4\/article-p557.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4]]},"references-count":60,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.3171\/jns.2007.106.4.557","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[2007,4]]}}}