{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T07:32:09Z","timestamp":1782977529792,"version":"3.54.5"},"reference-count":36,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,4]]},"abstract":"<jats:p content-type=\"fine-print\">\n                    \u2713 Atypical teratoid\/rhabdoid tumors (AT\/RTs) are aggressive malignant tumors found in infants and young children. The tumor is characterized by the presence of a rhabdoid cell component in all cases, but the histological origin is still unclear. Recently, germline mutation of the\n                    <jats:italic>hSNF5\/INI1<\/jats:italic>\n                    gene has been reported in association with AT\/RTs.\n                  <\/jats:p>\n                  <jats:p content-type=\"fine-print\">\n                    The authors report a rare case of an intraocular AT\/RT followed by a fourth ventricular tumor. The results of immunohistochemical studies of the surgical specimens revealed the presence of an AT\/RT and from this finding the neural origin was inferred. A novel missense mutation of the\n                    <jats:italic>hSNF5\/INI1<\/jats:italic>\n                    gene was demonstrated by DNA analysis. High-dose chemotherapy with stem cell rescue was effective in treating this patient. The immunohistochemical relationship between rhabdoid cells and the neurogenic zone, which has not been described in AT\/RTs, is of great interest in view of the nature of rhabdoid cells.\n                  <\/jats:p>","DOI":"10.3171\/ped.2005.102.3.0299","type":"journal-article","created":{"date-parts":[[2010,8,27]],"date-time":"2010-08-27T06:00:52Z","timestamp":1282888852000},"page":"299-302","source":"Crossref","is-referenced-by-count":1,"title":["Multicentric atypical teratoid\/rhabdoid tumors occurring in the eye and fourth ventricle of an infant"],"prefix":"10.3171","volume":"102","author":[{"given":"Mitsugu","family":"Fujita","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miho","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuko","family":"Kudo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuro","family":"Nagasaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaaki","family":"Mizuno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emi","family":"Amano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoko","family":"Okamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiro","family":"Hotta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisashi","family":"Hatano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norimoto","family":"Nakahara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshihiko","family":"Wakabayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Pediatr Hematol Oncol","doi-asserted-by":"publisher","first-page":"33","DOI":"10.3109\/08880019109033425","article-title":"Malignant rhabdoid tumor of the kidney presenting as intraocular metastasis.","volume":"8","author":"Akhtar","year":"1991"},{"key":"b2","series-title":"Cancer","doi-asserted-by":"publisher","first-page":"2137","DOI":"10.1002\/1097-0142(19841115)54:10<2137::AID-CNCR2820541014>3.0.CO;2-D","article-title":"The association of embryonal tumors originating in the kidney and in the brain. 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