{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T10:49:08Z","timestamp":1782211748724,"version":"3.54.5"},"reference-count":26,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,4]]},"abstract":"<jats:p content-type=\"fine-print\">\u2713Craniopharyngioma is a common sellar region tumor occurring in children. It usually manifests as endocrinological deficits such as short stature, delayed puberty, and obesity. Patients with craniopharyngioma commonly present with visual deficits and hydrocephalus.<\/jats:p>\n                  <jats:p content-type=\"fine-print\">The authors present the case of a child who presented with short stature and clinical evidence of Cushing disease (CD) associated with a suprasellar tumor. The patient underwent insertion of an Ommaya reservoir into the tumor's cystic portion. High adrenocorticotropic hormone (ACTH) levels were demonstrated within the cyst's fluid and in the serum. After adequate decompression of the tumor, the patient underwent total resection. The tumor pathology was compatible with an adamantinomatous craniopharyngioma and immunohistochemical studies failed to show staining for ACTH. Panhypopituitarism developed postoperatively in the patient and he received hormone substitution therapy with final adequate height and normal-high weight.<\/jats:p>\n                  <jats:p content-type=\"fine-print\">The neurosurgical implications of CD along with a possible mechanism for this patient's presentation are discussed in detail on the basis of the pertinent literature.<\/jats:p>","DOI":"10.3171\/ped.2005.102.3.0318","type":"journal-article","created":{"date-parts":[[2010,8,27]],"date-time":"2010-08-27T06:00:52Z","timestamp":1282888852000},"page":"318-321","source":"Crossref","is-referenced-by-count":2,"title":["Craniopharyngioma and Cushing disease"],"prefix":"10.3171","volume":"102","author":[{"given":"Adrian","family":"Caceres","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron","family":"J. Reitman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadanori","family":"Tomita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Arch Dis Child","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1136\/adc.62.10.1077","article-title":"Cushing's disease and craniopharyngioma.","volume":"62","author":"Ackland","year":"1987"},{"key":"b2","series-title":"Surg Neurol","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/0090-3019(94)90369-7","article-title":"A case of Cushing's disease accompanied by Rathke's cleft cyst: the usefulness of cavernous sinus sampling in the localization of microadenoma.","volume":"42","author":"Arita","year":"1994"},{"key":"b3","series-title":"J Pediatr Endocrinol Metab","first-page":"869","article-title":"Endocrine sequelae of childhood craniopharyngioma.","volume":"14","author":"Bin-Abbas","year":"2001"},{"key":"b4","series-title":"Pediatr Neurosurg","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1159\/000028679","article-title":"Suprasellar germinoma associated with Cushing's disease and diabetes insipidus in a child.","volume":"29","author":"Coufal","year":"1998"},{"key":"b5","series-title":"J Pediatr Endocrinol Metab","first-page":"703","article-title":"Craniopharyngioma: presentation and endocrine sequelae in 36 children.","volume":"16","author":"de Vries","year":"2003"},{"key":"b6","series-title":"Acta Radiol","first-page":"685","article-title":"Cushing's disease and sphenoidal aspergilloma. A case report.","volume":"44","author":"Gondim","year":"2003"},{"key":"b7","series-title":"Acta Neuropathol (Berl)","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1007\/BF00688240","article-title":"Immunohistochemical study of Rathke's cleft cyst.","volume":"77","author":"Ikeda","year":"1988"},{"key":"b8","series-title":"Cushing's Syndrome.","author":"Krieger","year":"1982"},{"key":"b9","series-title":"Neurosurgery","first-page":"920","article-title":"Cushing's disease in a child caused by a corticotropin-releasing hormone-secreting intrasellar gangliocytoma associated with an adrenocorticotropic hormone-secreting pituitary adenoma.","volume":"33","author":"Puchner","year":"1993"},{"key":"b10","series-title":"Klin Padiatr","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1055\/s-2002-33983","article-title":"Klinische symptome und befunde zum zeitpunkt der diagnosestellung bei kindern und jugendlichen mit kraniopharyngeom.","volume":"214","author":"Rohrer","year":"2002"},{"key":"b11","series-title":"Surg Neurol","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1016\/0090-3019(91)90090-V","article-title":"Secretory component of cystic craniopharyngiomas: a mucino-histochemical and electron-microscopic study.","volume":"36","author":"Szeifert","year":"1991"},{"key":"b12","series-title":"Neurol Res","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1080\/01616412.1993.11740111","article-title":"Could craniopharyngiomas produce pituitary hormones?","volume":"15","author":"Szeifert","year":"1993"},{"key":"b13","series-title":"Endocr Pathol","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1007\/BF02739956","article-title":"Pituitary adenoma with cholesterol clefts.","volume":"9","author":"Yokoyama","year":"1998"},{"key":"b1","series-title":"Arch Dis Child","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1136\/adc.62.10.1077","article-title":"Cushing's disease and craniopharyngioma.","volume":"62","author":"Ackland","year":"1987"},{"key":"b2","series-title":"Surg Neurol","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/0090-3019(94)90369-7","article-title":"A case of Cushing's disease accompanied by Rathke's cleft cyst: the usefulness of cavernous sinus sampling in the localization of microadenoma.","volume":"42","author":"Arita","year":"1994"},{"key":"b3","series-title":"J Pediatr Endocrinol Metab","first-page":"869","article-title":"Endocrine sequelae of childhood craniopharyngioma.","volume":"14","author":"Bin-Abbas","year":"2001"},{"key":"b4","series-title":"Pediatr Neurosurg","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1159\/000028679","article-title":"Suprasellar germinoma associated with Cushing's disease and diabetes insipidus in a child.","volume":"29","author":"Coufal","year":"1998"},{"key":"b5","series-title":"J Pediatr Endocrinol Metab","first-page":"703","article-title":"Craniopharyngioma: presentation and endocrine sequelae in 36 children.","volume":"16","author":"de Vries","year":"2003"},{"key":"b6","series-title":"Acta Radiol","first-page":"685","article-title":"Cushing's disease and sphenoidal aspergilloma. 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