{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T08:40:28Z","timestamp":1784191228676,"version":"3.55.0"},"reference-count":34,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,7]]},"abstract":"<jats:p>\n                    \u2713\n                    <jats:italic>Scedosporium apiospermum<\/jats:italic>\n                    is a fungus found in the soil and in contaminated water. Common cutaneous manifestations include Madura foot, a painless swelling on the sole of the foot. Invasive infection is usually associated with immunosuppression.\n                  <\/jats:p>\n                  <jats:p>\n                    The authors present a 16-month-old immunocompetent boy who had a near-drowning event. Following this, he was severely disabled with spastic quadriparesis. Early computerized tomography scans revealed diffuse hypoxic injury. Magnetic resonance images obtained 3 months after the initial event demonstrated multiple ring-enhancing lesions in the brain. Aspiration of the lesion was performed.\n                    <jats:italic>Scedosporium apiospermum<\/jats:italic>\n                    , the asexual form of\n                    <jats:italic>Pseudallescheria boydii<\/jats:italic>\n                    , was cultured. Conventional antifungal agents were commenced, with minimal effect. The child was subsequently treated with a new antifungal agent, voriconazole, a broad-spectrum triazole antifungal agent with good penetration into the cerebrospinal fluid. The patient improved, with a good radiological outcome and a moderate clinical outcome. The authors review the use of voriconazole for central nervous system infections and review the literature on\n                    <jats:italic>S. apiospermum<\/jats:italic>\n                    associated with near drowning.\n                  <\/jats:p>","DOI":"10.3171\/ped.2005.103.1.0083","type":"journal-article","created":{"date-parts":[[2010,8,27]],"date-time":"2010-08-27T06:01:30Z","timestamp":1282888890000},"page":"83-87","source":"Crossref","is-referenced-by-count":3,"title":["Scedosporium apiospermum brain abscess treated with surgery and voriconazole"],"prefix":"10.3171","volume":"103","author":[{"given":"Aabir","family":"Chakraborty","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Rella","family":"Workman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter R.","family":"Bullock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"J Radiol","first-page":"321","article-title":"An\u00e9vrysmes mycotiques fongiques et abc\u00e8s c\u00e9r\u00e9braux multiples \u00e0 Scedosporium apiospermum. A propos d'une observation avec revue de la literature.","volume":"66","author":"Baudrillard","year":"1985"},{"key":"b2","series-title":"Arch Neurol","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1001\/archneur.1978.00500300060011","article-title":"Allescheria (Petriellidium) boydii brain abscess in a child with leukemia.","volume":"35","author":"Bell","year":"1978"},{"key":"b3","series-title":"Medicine","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1097\/00005792-200209000-00001","article-title":"Pseudallescheria boydii (Anamorph Scedosponium apiospermum). Infection in solid organ transplant recipients in a tertiary medical center and review of the literature.","volume":"81","author":"Castiglioni","year":"2002"},{"key":"b4","series-title":"Can J Neurol Sci","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1017\/S0317167100045790","article-title":"Brain abscess due to Petriellidium boydii.","volume":"11","author":"Dubeau","year":"1984"},{"key":"b5","series-title":"Medicine","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1097\/00005792-198907000-00004","article-title":"Pseudallescheria boydii brain abscess: association with near-drowning and efficacy of high-dose, prolonged miconazole therapy in patients with multiple abscesses.","volume":"68","author":"Dworzack","year":"1989"},{"key":"b6","series-title":"Arch Neurol","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1001\/archneur.1982.00510200053011","article-title":"Near-drowning complicated by brain abscess due to Petriellidium boydii.","volume":"39","author":"Fisher","year":"1982"},{"key":"b7","series-title":"J Pathol","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1002\/path.1711060307","article-title":"Allescheria boydii infection of the brain.","volume":"106","author":"Forno","year":"1972"},{"key":"b8","series-title":"Sabouraudia","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1080\/00362178585380531","article-title":"Scedosporum (Monosporium) apiospermum: multiple brain abscesses.","volume":"23","author":"Gari","year":"1985"},{"key":"b9","series-title":"Pediatr Infect Dis J","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1097\/00006454-199010000-00011","article-title":"Pseudallescheria boydii and brain abscesses.","volume":"9","author":"Hachimi-Idrissi","year":"1990"},{"key":"b10","series-title":"Clin Infect Dis","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1086\/314042","article-title":"Pseudallescheria boydii brain abscess successfully treated with voriconazole and surgical drainage: case report and literature review of central nervous system pseudallescheriasis.","volume":"31","author":"Nesky","year":"2000"},{"key":"b11","series-title":"J Antimicrob Chemother","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1093\/jac\/18.4.473","article-title":"Antifungal effects of fluconazole (UK 49858), a new triazole antifungal, in vitro.","volume":"18","author":"Odds","year":"1986"},{"key":"b12","series-title":"Mycoses","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1111\/j.1439-0507.1995.tb00022.x","article-title":"Cerebral Pseudallescheria mycosis after near-drowning.","volume":"38","author":"R\u00fcchel","year":"1995"},{"key":"b13","series-title":"Br J Haematol","first-page":"663","article-title":"Successful treatment of cerebral aspergillosis with a novel triazole (voriconazole) in a patient with acute leukaemia.","volume":"97","author":"Schwartz","year":"1997"},{"key":"b14","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"225","DOI":"10.3171\/jns.1972.36.2.0225","article-title":"Pachymeningitis secondary to Allescheria boydii. Case report.","volume":"36","author":"Selby","year":"1972"},{"key":"b15","series-title":"Mayo Clin Proc","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1016\/S0025-6196(12)60571-0","article-title":"Clinical significance of Pseudallescheria boydii: a review of 10 years' experience.","volume":"60","author":"Travis","year":"1985"},{"key":"b16","series-title":"Am J Med","doi-asserted-by":"publisher","first-page":"830","DOI":"10.1016\/0002-9343(77)90170-X","article-title":"Allescheria boydii infections in the immunosuppressed host.","volume":"63","author":"Winston","year":"1977"},{"key":"b17","series-title":"Rev Infect Dis","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1093\/clinids\/7.2.272","article-title":"Brain abscesses due to Pseudallescheria boydii associated with primary non-Hodgkin's lymphoma of the central nervous system: a case report and literature review.","volume":"7","author":"Yoo","year":"1985"},{"key":"b1","series-title":"J Radiol","first-page":"321","article-title":"An\u00e9vrysmes mycotiques fongiques et abc\u00e8s c\u00e9r\u00e9braux multiples \u00e0 Scedosporium apiospermum. A propos d'une observation avec revue de la literature.","volume":"66","author":"Baudrillard","year":"1985"},{"key":"b2","series-title":"Arch Neurol","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1001\/archneur.1978.00500300060011","article-title":"Allescheria (Petriellidium) boydii brain abscess in a child with leukemia.","volume":"35","author":"Bell","year":"1978"},{"key":"b3","series-title":"Medicine","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1097\/00005792-200209000-00001","article-title":"Pseudallescheria boydii (Anamorph Scedosponium apiospermum). Infection in solid organ transplant recipients in a tertiary medical center and review of the literature.","volume":"81","author":"Castiglioni","year":"2002"},{"key":"b4","series-title":"Can J Neurol Sci","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1017\/S0317167100045790","article-title":"Brain abscess due to Petriellidium boydii.","volume":"11","author":"Dubeau","year":"1984"},{"key":"b5","series-title":"Medicine","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1097\/00005792-198907000-00004","article-title":"Pseudallescheria boydii brain abscess: association with near-drowning and efficacy of high-dose, prolonged miconazole therapy in patients with multiple abscesses.","volume":"68","author":"Dworzack","year":"1989"},{"key":"b6","series-title":"Arch Neurol","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1001\/archneur.1982.00510200053011","article-title":"Near-drowning complicated by brain abscess due to Petriellidium boydii.","volume":"39","author":"Fisher","year":"1982"},{"key":"b7","series-title":"J Pathol","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1002\/path.1711060307","article-title":"Allescheria boydii infection of the brain.","volume":"106","author":"Forno","year":"1972"},{"key":"b8","series-title":"Sabouraudia","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1080\/00362178585380531","article-title":"Scedosporum (Monosporium) apiospermum: multiple brain abscesses.","volume":"23","author":"Gari","year":"1985"},{"key":"b9","series-title":"Pediatr Infect Dis J","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1097\/00006454-199010000-00011","article-title":"Pseudallescheria boydii and brain abscesses.","volume":"9","author":"Hachimi-Idrissi","year":"1990"},{"key":"b10","series-title":"Clin Infect Dis","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1086\/314042","article-title":"Pseudallescheria boydii brain abscess successfully treated with voriconazole and surgical drainage: case report and literature review of central nervous system pseudallescheriasis.","volume":"31","author":"Nesky","year":"2000"},{"key":"b11","series-title":"J Antimicrob Chemother","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1093\/jac\/18.4.473","article-title":"Antifungal effects of fluconazole (UK 49858), a new triazole antifungal, in vitro.","volume":"18","author":"Odds","year":"1986"},{"key":"b12","series-title":"Mycoses","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1111\/j.1439-0507.1995.tb00022.x","article-title":"Cerebral Pseudallescheria mycosis after near-drowning.","volume":"38","author":"R\u00fcchel","year":"1995"},{"key":"b13","series-title":"Br J Haematol","first-page":"663","article-title":"Successful treatment of cerebral aspergillosis with a novel triazole (voriconazole) in a patient with acute leukaemia.","volume":"97","author":"Schwartz","year":"1997"},{"key":"b14","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"225","DOI":"10.3171\/jns.1972.36.2.0225","article-title":"Pachymeningitis secondary to Allescheria boydii. Case report.","volume":"36","author":"Selby","year":"1972"},{"key":"b15","series-title":"Mayo Clin Proc","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1016\/S0025-6196(12)60571-0","article-title":"Clinical significance of Pseudallescheria boydii: a review of 10 years' experience.","volume":"60","author":"Travis","year":"1985"},{"key":"b16","series-title":"Am J Med","doi-asserted-by":"publisher","first-page":"830","DOI":"10.1016\/0002-9343(77)90170-X","article-title":"Allescheria boydii infections in the immunosuppressed host.","volume":"63","author":"Winston","year":"1977"},{"key":"b17","series-title":"Rev Infect Dis","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1093\/clinids\/7.2.272","article-title":"Brain abscesses due to Pseudallescheria boydii associated with primary non-Hodgkin's lymphoma of the central nervous system: a case report and literature review.","volume":"7","author":"Yoo","year":"1985"}],"container-title":["Journal of Neurosurgery: Pediatrics"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-pediatr\/103\/1\/article-p83.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-pediatr\/103\/1\/article-p83.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-pediatr\/103\/1\/article-p83.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T10:19:34Z","timestamp":1782209974000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-pediatr\/103\/1\/article-p83.xml"}},"subtitle":["Case report"],"short-title":[],"issued":{"date-parts":[[2005,7]]},"references-count":34,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.3171\/ped.2005.103.1.0083","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[2005,7]]}}}