{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T10:49:29Z","timestamp":1782211769084,"version":"3.54.5"},"reference-count":46,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,9]]},"abstract":"<jats:p>\n                    \u2713Juvenile hyaline fibromatosis (JHF) is a rare systemic disease characterized by papulonodular skin lesions, gingival hyperplasia, joint contractures, and osteolytic lesions on long bones and the skull. It has recently been reported that the disease is caused by mutations in the gene encoding\n                    <jats:italic>capillary morphogenesis protein\u20142 (CMG-2)<\/jats:italic>\n                    . To date, fewer than 60 cases have been published in the literature. Partial disease expression is common, but no cases featuring a solitary calvarial lesion have been reported.\n                  <\/jats:p>\n                  <jats:p>\n                    The authors discuss this 4-year-old boy with a solitary calvarial osteolytic lesion whose histopathological examination exhibited findings characteristic of JHF. Mutational analysis, however, revealed that there were no mutations in the\n                    <jats:italic>CMG-2<\/jats:italic>\n                    gene. Two years after surgery, he was free of any complaints as well as gingival hyperplasia, joint contractures, and new skull or skin lesions. This patient's condition may represent clinical or genetic heterogeneity associated with JHF. Whether solitary lesions mimicking JHF can arise from somatic mutation of the\n                    <jats:italic>CMG-2<\/jats:italic>\n                    gene remains to be proven.\n                  <\/jats:p>","DOI":"10.3171\/ped.2005.103.3.0285","type":"journal-article","created":{"date-parts":[[2010,8,27]],"date-time":"2010-08-27T06:01:35Z","timestamp":1282888895000},"page":"285-288","source":"Crossref","is-referenced-by-count":0,"title":["A solitary calvarial lytic lesion with typical histopathological findings of juvenile hyaline fibromatosis"],"prefix":"10.3171","volume":"103","author":[{"given":"N.","family":"Serdar Bas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feyza","family":"Karag\u00f6z G\u00fczey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erhan","family":"Emel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kivanc","family":"Cefle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00fcrriyet","family":"Turgut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim","family":"Alatas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baris","family":"Sel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sukru","family":"Palanduz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sukru","family":"Ozturk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serap","family":"Cetinkaya Bas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"J Cell Sci","doi-asserted-by":"publisher","first-page":"2755","DOI":"10.1242\/jcs.114.15.2755","article-title":"Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling.","volume":"114","author":"Bell","year":"2001"},{"key":"b2","series-title":"Int J Pediatr Otorhinolaryngol","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1016\/S0165-5876(03)00017-X","article-title":"Juvenile hyaline fibromatosis: a case report.","volume":"67","author":"Caylakli","year":"2003"},{"key":"b3","series-title":"Am J Dermatopathol","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1097\/00000372-199412000-00009","article-title":"Juvenile hyaline fibromatosis. 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Ultrastructural and biochemical study of cultured skin fibroblasts.","volume":"267","author":"Iwata","year":"1980"},{"key":"b11","series-title":"Clin Rheumatol","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1007\/s100670050094","article-title":"Two siblings with juvenile hyaline fibromatosis: case reports and review of the literature.","volume":"18","author":"Keser","year":"1999"},{"key":"b12","series-title":"Arch Dermatol","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1001\/archderm.1976.01630250050016","article-title":"Juvenile hyalin fibromatosis.","volume":"112","author":"Kitano","year":"1976"},{"key":"b13","series-title":"Pediatr Dermatol","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1046\/j.1525-1470.2001.01964.x","article-title":"Juvenile hyaline fibromatosis.","volume":"18","author":"Larralde","year":"2001"},{"key":"b14","series-title":"Arch Dis Child","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1136\/adc.73.3.246","article-title":"Skin collagen defects in a patient with juvenile hyaline fibromatosis.","volume":"73","author":"Lubec","year":"1995"},{"key":"b15","series-title":"Arch Dermatol","doi-asserted-by":"publisher","first-page":"1062","DOI":"10.1001\/archderm.1985.01660080116028","article-title":"Juvenile hyaline fibromatosis. 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A case report.","volume":"74","author":"Suzuki","year":"1992"},{"key":"b20","series-title":"Modern Surgical Pathology.","first-page":"1802","year":"2003"},{"key":"b21","series-title":"Am J Dermatopathol","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1097\/00000372-199808000-00009","article-title":"Juvenile hyaline fibromatosis ultrastructural study.","volume":"20","author":"Winik","year":"1998"},{"key":"b22","series-title":"J Pediatr Surg","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1016\/S0022-3468(84)80192-X","article-title":"A 19-year follow-up of multiple juvenile hyaline fibromatosis.","volume":"19","author":"Woyke","year":"1984"},{"key":"b23","series-title":"Int J Dermatol","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1111\/j.1365-4362.1984.tb05703.x","article-title":"Juvenile hyaline fibromatosis.","volume":"23","author":"Yesudian","year":"1984"}],"container-title":["Journal of Neurosurgery: Pediatrics"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-pediatr\/103\/3\/article-p285.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-pediatr\/103\/3\/article-p285.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-pediatr\/103\/3\/article-p285.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T10:20:00Z","timestamp":1782210000000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-pediatr\/103\/3\/article-p285.xml"}},"subtitle":["Case report"],"short-title":[],"issued":{"date-parts":[[2005,9]]},"references-count":46,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.3171\/ped.2005.103.3.0285","relation":{},"ISSN":["0022-3085"],"issn-type":[{"value":"0022-3085","type":"print"}],"subject":[],"published":{"date-parts":[[2005,9]]}}}