{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T13:07:06Z","timestamp":1770901626643,"version":"3.50.1"},"reference-count":25,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["SPI"],"published-print":{"date-parts":[[2007,8]]},"abstract":"<jats:p>\u2713Hemangioblastomas are low-grade, highly vascular tumors commonly associated with von Hippel\u2013Lindau (VHL) syndrome and most often appearing in the cerebellum. They very rarely occur in the spinal nerve roots, and an origin in the filum terminale is exceptional with no instances of multiple hemangioblastomas of the filum terminale reported in the literature. Because of their vascular nature, these lesions can enlarge and become symptomatic in the context of the changes that take place during pregnancy, as has been noted with cerebellar hemangioblastomas. In any case, the evolution of spinal hemangioblastomas during pregnancy is not well known given its rarity. The conjunction of both processes\u2014that is, multiple hemangioblastomas arising in the filum terminale and pregnancy\u2014is unique. The authors describe the case of a 41-year-old woman with multiple hemangioblastomas of the filum terminale and no other evidence of VHL syndrome, in whom pregnancy precipitated symptoms. The interruption of gestation led to a remission of the symptoms. The literature concerning filum terminale hemangioblastomas and pregnancy is also reviewed.<\/jats:p>","DOI":"10.3171\/spi-07\/08\/254","type":"journal-article","created":{"date-parts":[[2008,1,24]],"date-time":"2008-01-24T13:19:02Z","timestamp":1201180742000},"page":"254-258","source":"Crossref","is-referenced-by-count":22,"title":["Multiple filum terminale hemangioblastomas symptomatic during pregnancy"],"prefix":"10.3171","volume":"7","author":[{"given":"Marta","family":"Ortega-Mart\u00ednez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose M.","family":"Cabezudo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignacio","family":"Fern\u00e1ndez-Portales","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Pineda-Palomo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Antonio","family":"Rodr\u00edguez-S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis Miguel","family":"Bernal-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-0070254","series-title":"AJR Am J Roentgenol","doi-asserted-by":"publisher","first-page":"857","DOI":"10.2214\/ajr.173.3.10470964","article-title":"Hemangioblastoma of the filum terminale: MR imaging","volume":"173","author":"Arbelaez","year":"1999"},{"key":"b2-0070254","series-title":"Acta Neurochir (Wien)","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1007\/s007010070063","article-title":"Extramedullary hemangioblastoma of the conus medullaris","volume":"142","author":"Brisman","year":"2000"},{"key":"b3-0070254","series-title":"Mod Pathol","first-page":"55","article-title":"Hormone receptor immunoreactivity in hemangioblastomas and clear cell renal cell carcinomas","volume":"11","author":"Brown","year":"1998"},{"key":"b4-0070254","series-title":"Arch Neurol","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1001\/archneur.1976.00500060041009","article-title":"Hemangioblastoma of the spinal cord. 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