{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T20:42:55Z","timestamp":1793997775695,"version":"4.8.0"},"reference-count":10,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["SPI"],"published-print":{"date-parts":[[2008,1]]},"abstract":"\nObject<\/jats:title>\nPatient selection is perhaps the most important factor in successful lumbar surgery. In this study, the authors analyzed the clinical outcomes of patients enrolled in the CHARIT\u00c9 investigational device exemption (IDE) trial who underwent revision surgery after primary total disc replacement with CHARIT\u00c9 or an anterior lumbar interbody fusion (ALIF) with placement of a BAK cage and iliac crest autograft. This revision surgery was either a supplemental posterior lumbar fixation or a 360\u00b0 fusion. Statistical analysis was conducted to compare clinical success in patients who underwent revision surgery with those who did not.<\/jats:p><\/jats:sec>\n\nMethods<\/jats:title>\nThe patients enrolled in the CHARIT\u00c9 IDE study were divided into 6 groups according to treatment and repeated operation status, and their Oswestry Disability Index (ODI) and visual analog scale (VAS) scores at the 2-year follow-up and at baseline were compared. The patients had received the following treatments by group: A) ALIF without reoperation; B) ALIF with conversion to 360\u00b0 fusion; C) arthroplasty (randomized) without repeated operation; D) arthroplasty with supplemental posterior lumbar fixation; E) arthroplasty (nonrandomized) without repeated operation; and F) arthroplasty (nonrandomized) with supplemental posterior lumbar fixation. Outcome scores in the groups of patients who required revision surgeries (Groups B, D, and F; 23 patients) were compared with the groups that did not require revision surgery (Groups A, C, and E; 299 patients).<\/jats:p><\/jats:sec>\n\nResults<\/jats:title>\nPatients who required revision surgery had a significantly lower level of clinical improvement than those who did not. The mean change in ODI score was \u221253.0% in Groups A, C, and E, but just \u221212.7% in Groups B, D, and F (p < 0.0001). The mean change in VAS score was \u221259.1% in Groups A, C, and E, compared to \u221223.4% in Groups B, D, and F (p < 0.0001). No significant differences were identified in analyzing absolute change in scores and the percentage change. A comparison of outcomes in patients who had undergone arthroplasty without reoperation (Groups C and E) with all patients who had undergone revision surgery (Groups B, D, and F) demonstrated similar results (p < 0.0001).<\/jats:p><\/jats:sec>\n\nConclusions<\/jats:title>\nThe 7.1% of patients who underwent a secondary stabilization procedure had poor clinical improvement. This finding may indicate that if the alternative treatment had been the initial treatment, these patients would not have benefited, and further implies a 7.1% rate of imprecision in preoperative evaluation.<\/jats:p><\/jats:sec>","DOI":"10.3171\/spi-08\/01\/013","type":"journal-article","created":{"date-parts":[[2008,1,2]],"date-time":"2008-01-02T13:41:36Z","timestamp":1199281296000},"page":"13-16","source":"Crossref","is-referenced-by-count":21,"title":["Patient selection for lumbar arthroplasty and arthrodesis: the effect of revision surgery in a controlled, multicenter, randomized study"],"prefix":"10.3171","volume":"8","author":[{"given":"Fred H.","family":"Geisler","sequence":"first","affiliation":[{"name":"1Illinois Neuro-Spine Center, Aurora, Illinois;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard D.","family":"Guyer","sequence":"additional","affiliation":[{"name":"2Texas Back Institute, Plano, Texas;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott L.","family":"Blumenthal","sequence":"additional","affiliation":[{"name":"2Texas Back Institute, Plano, Texas;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul C.","family":"McAfee","sequence":"additional","affiliation":[{"name":"3Spine and Scoliosis Center, Towson, Maryland;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Cappuccino","sequence":"additional","affiliation":[{"name":"4Buffalo Spine Surgery, Lockport, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabien","family":"Bitan","sequence":"additional","affiliation":[{"name":"5Lennox Hill Hospital, New York, New York; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John J.","family":"Regan","sequence":"additional","affiliation":[{"name":"6Goldstein and Penenberg Orthopedic Associates, Beverly Hills, California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-0080013","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000170587.32676.0e"},{"key":"b2-0080013","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000108423.87889.9E"},{"key":"b3-0080013","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199710150-00019"},{"issue":"1","key":"b4-0080013","doi-asserted-by":"crossref","first-page":"ONS46","DOI":"10.1227\/01.NEU.0000145785.69942.B3","volume":"56","author":"Geisler FH","year":"2005","journal-title":"Neurosurgery"},{"key":"b5-0080013","doi-asserted-by":"publisher","DOI":"10.3171\/spi.2004.1.2.0143"},{"key":"b6-0080013","doi-asserted-by":"publisher","DOI":"10.3171\/spi.2004.1.3.0267"},{"key":"b7-0080013","doi-asserted-by":"publisher","DOI":"10.3171\/spi.2006.5.4.281"},{"key":"b8-0080013","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000144408.02918.20"},{"key":"b9-0080013","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000170561.25636.1c"},{"key":"b10-0080013","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4637.2002.02033.x"}],"container-title":["Journal of Neurosurgery: Spine"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-spine\/8\/1\/article-p13.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-spine\/8\/1\/article-p13.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,13]],"date-time":"2020-11-13T23:31:33Z","timestamp":1605310293000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-spine\/8\/1\/article-p13.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1]]},"references-count":10,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.3171\/spi-08\/01\/013","relation":{},"ISSN":["1547-5654"],"issn-type":[{"value":"1547-5654","type":"print"}],"subject":[],"published":{"date-parts":[[2008,1]]}}}