{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T02:25:04Z","timestamp":1792635904516,"version":"4.5.0"},"reference-count":44,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2001,7]]},"abstract":"<jats:p content-type=\"fine-print\"><jats:italic>Object.<\/jats:italic> The authors have previously reported that the results of using cadaveric fibula and locking plate (CF\/LP) fusion following anterior cervical discectomy (ACD) for cervical spondylotic radiculopathy and myelopathy are superior to those obtained using autologous iliac crest (AIC) grafts in the short term. The long-term results of using this construct are important in substantiating this improvement. The authors report on 246 consecutive patients (54% smokers) who underwent ACD with CF\/LP fusion (175 with allogeneic bone matrix [ABM]) and compare them with 111 consecutive patients in whom AIC fusions (49% smokers) were performed by the same surgeons.<\/jats:p>\n<jats:p content-type=\"fine-print\"><jats:italic>Methods.<\/jats:italic> The study is a retrospective nonrandomized analysis, and chi-square statistics were used. Bone densitometric studies of AIC grafts and CF grafts were performed. A paired t-test was used for statistical analysis of the results. Disease in the group of patients undergoing CF\/LP fusion included soft-disc herniation with radiculopathy in 14, soft-disc herniation with myelopathy in seven, cervical spondylotic radiculopathy in 144, cervical spondylotic myelopathy in 75, AIC graft collapse pseudarthrosis in five, and ACD with no fusion collapse\/kyphosis in one. Operations consisted of single-level CF\/LP fusion in 142 patients and multilevel CF\/LP fusion in 104. Perioperative complications in the CF\/LP group included three cases of transient hoarseness. There were no transfusions, infections, neurological injuries, or deaths. The mean hospital length of stay was 1.2 days (28% outpatient and 66% 23-hour stay). The mean follow-up period was 60 months (range 12\u201394 months). Ten patients were lost to follow up after 1 year. Long-term complications included one traumatic plate fracture and one symptomatic pseudarthrosis with plate fracture. At 1 year and beyond, in 245 (99.6%) of 246 patients radiographically documented fusion with no motion at the fused level on flexion\u2014extension films was demonstrated. There was no kyphosis, no symptomatic screw plate backout, and no CF\/LP graft collapse (100% in the ABM group). In the 111 consecutive patients with AIC fusions, however, there was a 17% graft-related complication rate. There were significantly fewer graft-related complications in the CF\/LP group (p &lt; 0.001). There was no difference in neurological outcome for any of the groups. In the groups undergoing single-level ACD there was a significantly greater chance of complete relief of neck pain CF\/LP fusion compared with those undergoing AIC fusion (p &lt; 0.02). There was a significantly greater chance of AIC collapse with the passage of time compared with CF graft (p &lt; 0.02). Time until return to work was shorter for the CF\/LP group by 5 to 6 weeks (p &lt; 0.02). There was a higher rate of radiographically documented pseudarthrosis in the AIC group (p &lt; 0.006). The mean bone densitometry for the CF\/LP group was 0.7 g\/cm<jats:sup>2<\/jats:sup>, significantly greater than that of the AIC group, which was 0.2 g\/cm<jats:sup>2<\/jats:sup> (paired t-test p &lt; 0.001).<\/jats:p>\n<jats:p content-type=\"fine-print\"><jats:italic>Conclusions.<\/jats:italic> When fusion is necessary following ACD, the results of CF\/LP fusion are significantly superior in the first 5 years after surgery compared with those for AIC fusions. It remains to be determined if demineralized ABM has a significant effect in enhancing fusion.<\/jats:p>","DOI":"10.3171\/spi.2001.95.1.0043","type":"journal-article","created":{"date-parts":[[2009,5,7]],"date-time":"2009-05-07T15:53:32Z","timestamp":1241711612000},"page":"43-50","source":"Crossref","is-referenced-by-count":13,"title":["Cadaveric fibula, locking plate, and allogeneic bone matrix for anterior cervical fusions after cervical discectomy for radiculopathy or myelopathy"],"prefix":"10.3171","volume":"95","author":[{"given":"Scott","family":"Shapiro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Connolly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jill","family":"Donnaldson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd","family":"Abel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Spine","doi-asserted-by":"publisher","first-page":"2211","DOI":"10.1097\/00007632-199510001-00006","article-title":"Comparison between allograft plus demineralized bone matrix versus autograft in anterior cervical fusion. 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