{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T11:01:59Z","timestamp":1780052519347,"version":"3.53.1"},"reference-count":20,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2002,9]]},"abstract":"<jats:p content-type=\"fine-print\"><jats:italic>Object.<\/jats:italic> In these prospective and retrospective studies the authors evaluated trauma-induced myelopathy in patients with ossification of the posterior longitudinal ligament (OPLL) to determine the effectiveness of preventive surgery for this disease.<\/jats:p>\n<jats:p content-type=\"fine-print\"><jats:italic>Methods.<\/jats:italic> The authors studied 552 patients with cervical OPLL, including 184 with myelopathy at the time of initial consultation and 368 patients without myelopathy at that time. In the former group of 184 patients retrospective analysis was performed using an interview survey to ascertain the relationship between onset of myelopathy and trauma. In the latter group of 368 patients prospective examination was conducted by assessing radiographic findings and noting changes in clinical symptoms apparent during regular physical examination. The follow-up period ranged from 10 to 32 years (mean 19.6 years).<\/jats:p>\n<jats:p content-type=\"fine-print\">In the retrospective investigation, 24 patients (13%) identified cervical trauma as the trigger of their myelopathy. In the prospective investigation, 70% of patients did not develop myelopathy over a follow-up period greater than 20 years (determined using the Kaplan\u2014Meier method). Of the 368 patients without myelopathy at the time of initial consultation, only six patients (2%) subsequently developed trauma-induced myelopathy. Types of ossification in patients who developed trauma-induced myelopathy were primarily a mixed type. All patients in whom stenosis affected 60% or greater of the spinal canal developed myelopathy regardless of a history of trauma.<\/jats:p>\n<jats:p content-type=\"fine-print\"><jats:italic>Conclusions.<\/jats:italic> Preventive surgery prior to onset of myelopathy is unnecessary in most patients with OPLL.<\/jats:p>","DOI":"10.3171\/spi.2002.97.2.0172","type":"journal-article","created":{"date-parts":[[2009,5,7]],"date-time":"2009-05-07T15:52:47Z","timestamp":1241711567000},"page":"172-175","source":"Crossref","is-referenced-by-count":15,"title":["Trauma-induced myelopathy in patients with ossification of the posterior longitudinal ligament"],"prefix":"10.3171","volume":"97","author":[{"given":"Shunji","family":"Matsunaga","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Sakou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoji","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Ishidou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masataka","family":"Hirotsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Setsuro","family":"Komiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"J Neurol Neurosurg Psychiatry","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1136\/jnnp.33.2.263","article-title":"Ossification in the region of the posterior longitudinal ligament as a cause of cervical myelopathy.","volume":"33","author":"Bakay","year":"1970"},{"key":"b2","series-title":"Spine","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1097\/00007632-199403001-00006","article-title":"Ossification of the posterior longitudinal ligament in evolution in 12 patients.","volume":"19","author":"Epstein","year":"1994"},{"key":"b3","series-title":"Spine","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1097\/00007632-199403001-00005","article-title":"The surgical management of ossification of the posterior longitudinal ligament in 43 north americans.","volume":"19","author":"Epstein","year":"1994"},{"key":"b4","series-title":"J Spinal Disord","first-page":"16","article-title":"Influence of minor trauma on surgical results in patients with cervical OPLL.","volume":"11","author":"Fujimura","year":"1998"},{"key":"b5","series-title":"J Amer Stat Assoc","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1080\/01621459.1958.10501452","article-title":"Nonparametric estimation from incomplete observation.","volume":"53","author":"Kaplan","year":"1958"},{"key":"b6","series-title":"Paraplegia","first-page":"330","article-title":"Influence of minor trauma to the neck on the neurological outcome in patients with ossification of the posterior longitudinal ligament (OPLL) of the cervical spine.","volume":"33","author":"Katoh","year":"1995"},{"key":"b7","series-title":"Clin Orthop","first-page":"168","article-title":"The natural course of myelopathy caused by ossification of the posterior longitudinal ligament in the cervical spine.","volume":"305","author":"Matsunaga","year":"1994"},{"key":"b8","series-title":"Am J Roentgenol Radium Ther Nucl Med","doi-asserted-by":"publisher","first-page":"365","DOI":"10.2214\/ajr.105.2.365","article-title":"Calcification of the posterior longitudinal ligament: a cause of cervical myelopathy.","volume":"105","author":"Minagi","year":"1969"},{"key":"b9","series-title":"Brain","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1093\/brain\/95.1.87","article-title":"The pathogenesis of the spinal cord disorder associated with cervical spondylosis.","volume":"95","author":"Nurick","year":"1972"},{"key":"b10","series-title":"Spine","doi-asserted-by":"publisher","first-page":"2024","DOI":"10.1097\/00007632-199310001-00016","article-title":"Magnetic resonance imaging study on the results of surgery for cervical compression myelopathy.","volume":"18","author":"Okada","year":"1993"},{"key":"b11","series-title":"J Bone Joint Surg (Am)","doi-asserted-by":"publisher","first-page":"1314","DOI":"10.2106\/00004623-196749070-00007","article-title":"Posterior paravertebral ossification causing cervical myelopathy. A report of eighteen cases.","volume":"49","author":"Onji","year":"1967"},{"key":"b12","series-title":"AJR Am J Roentgenol","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.2214\/ajr.131.6.1049","article-title":"Association of diffuse idiopathic skeletal hyperostosis (DISH) and calcification and ossification of the posterior longitudinal ligament.","volume":"131","author":"Resnick","year":"1978"},{"key":"b13","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1148\/15.3.513","article-title":"Diffuse idiopathic skeletal hyperostosis (DISH): Forestier's disease with extraspinal manifestations.","volume":"115","author":"Resnick","year":"1975"},{"key":"b14","series-title":"Spine","first-page":"1249","article-title":"Genetic study of ossification of the posterior longitudinal ligament in the cervical spine with human leukocyte antigen haplotype.","volume":"6","author":"Sakou","year":"1991"},{"key":"b15","series-title":"Spinal Cord","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1038\/sj.sc.3100595","article-title":"Clinical outcomes of cervical spinal cord injuries without radiographic evidence of trauma.","volume":"36","author":"Saruhashi","year":"1998"},{"key":"b16","series-title":"Clin Orthop","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1097\/00003086-199703000-00019","article-title":"3-dimensional computed tomography of ossification of the spinal ligament.","volume":"336","author":"Terada","year":"1997"},{"key":"b17","series-title":"Spine","doi-asserted-by":"publisher","first-page":"1184","DOI":"10.1097\/00007632-198911000-00009","article-title":"Genetic studies on ossification of then posterior longitudinal ligament of the spine.","volume":"14","author":"Terayama","year":"1989"},{"key":"b18","series-title":"Nihon Geka Hokan","first-page":"1003","article-title":"[On an autopsied case of compression myelopathy with a callus formation in the cervical spinal canal.]","volume":"29","author":"Tsukimoto","year":"1960"},{"key":"b19","series-title":"Clin Orthop","first-page":"71","article-title":"Ossification of the posterior longitudinal ligament of the spine.","volume":"184","author":"Tsuyama","year":"1984"},{"key":"b20","series-title":"Spine","doi-asserted-by":"publisher","first-page":"S388","DOI":"10.1097\/00007632-199210001-00008","article-title":"Preoperative and postoperative magnetic resonance image evaluations of the spinal cord in cervical myelopathy.","volume":"17","author":"Yone","year":"1992"}],"container-title":["Journal of Neurosurgery: Spine"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-spine\/97\/2\/article-p172.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-spine\/97\/2\/article-p172.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-spine\/97\/2\/article-p172.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T21:09:29Z","timestamp":1681592969000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-spine\/97\/2\/article-p172.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,9]]},"references-count":20,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.3171\/spi.2002.97.2.0172","relation":{},"ISSN":["1547-5654"],"issn-type":[{"value":"1547-5654","type":"print"}],"subject":[],"published":{"date-parts":[[2002,9]]}}}