{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,7]],"date-time":"2024-07-07T11:15:15Z","timestamp":1720350915651},"reference-count":11,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,7]]},"abstract":"\nObject<\/jats:italic><\/jats:title>\nThe goal of this study was to quantify volumetrically cement fill and leakage in patients with osteoporotic and metastatic vertebral lesions undergoing percutaneous vertebroplasty and to establish whether these factors have any clinical significance at follow up.<\/jats:p>\n<\/jats:sec>\n\nMethods<\/jats:italic><\/jats:title>\nDigital computerized tomography data were retrospectively collected from all cases at the authors' institution in which percutaneous vertebroplasty was performed for osteoporosis or metastatic disease. Patient selection was based on the consensus of a multidisciplinary team consisting of an orthopedic surgeon, an oncologist, and a neuroradiologist. A semiautomated thresholding technique was used to measure vertebral body volume, the volume of cement injected directly into the vertebra, and the volume of cement leakage. Pain-related scores were collected at four early stages of treatment, and all clinical complications were recorded.<\/jats:p>\nCement leakage was found in 87.9% of vertebrae treated with percutaneous vertebroplasty. In osteoporotic vertebrae it occurred mainly in the disc, whereas in metastatic lesions, it was found in multiple areas. Irrespective of leakage, both patients with osteoporotic and metastatic disease experienced significant immediate pain relief postoperatively.<\/jats:p>\n<\/jats:sec>\n\nConclusions<\/jats:italic><\/jats:title>\nAlthough there was no correlation between cement fill or cement leakage and pain relief, there exists a risk of serious complications due to cement leakage.<\/jats:p>\n<\/jats:sec>","DOI":"10.3171\/spi.2003.99.1.0056","type":"journal-article","created":{"date-parts":[[2009,5,7]],"date-time":"2009-05-07T15:57:33Z","timestamp":1241711853000},"page":"56-59","source":"Crossref","is-referenced-by-count":22,"title":["Volumetric quantification of cement leakage following percutaneous vertebroplasty in metastatic and osteoporotic vertebrae"],"prefix":"10.3171","volume":"99","author":[{"given":"Payam","family":"Mousavi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Roth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joel","family":"Finkelstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gordon","family":"Cheung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cari","family":"Whyne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Spine","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1097\/00007632-200203010-00005","article-title":"Fat embolism and acute hypotension during vertebroplasty: an experimental study in sheep.","volume":"27","author":"Aebli","year":"2002"},{"key":"b2","series-title":"Spine","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1097\/00007632-200004150-00005","article-title":"Percutaneous vertebroplasty for pain relief and spinal stabilization.","volume":"25","author":"Barr","year":"2000"},{"key":"b3","series-title":"J Bone Joint Surg Br","doi-asserted-by":"publisher","first-page":"748","DOI":"10.1302\/0301-620X.84B5.0840748","article-title":"Adjacent vertebral failure after vertebroplasty. A biomechanical investigation.","volume":"84","author":"Berlemann","year":"2002"},{"key":"b4","series-title":"J Neuroradiol","first-page":"45","article-title":"[Percutaneous vertebral surgery. Technics and indications.]","volume":"24","author":"Chiras","year":"1997"},{"key":"b5","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1148\/radiology.200.2.8685351","article-title":"Percutaneous vertebroplasty for osteolytic metastases and myeloma: effects of the percentage of lesion filling and the leakage of methyl methacrylate at clinical follow-up.","volume":"200","author":"Cotten","year":"1996"},{"key":"b6","series-title":"Radiol Clin North Am","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1016\/S0033-8389(05)70042-7","article-title":"Percutaneous vertebroplasty with polymethylmethacrylate. Technique, indications, and results.","volume":"36","author":"Deramond","year":"1998"},{"key":"b7","series-title":"International Journal of Cancer.","first-page":"135","article-title":"Prospective evaluation of functional status and quality of life in patients undergoing percutaneous vertebroplasty.","volume":"S13","author":"Holden","year":"2002"},{"key":"b8","series-title":"Spine","doi-asserted-by":"publisher","first-page":"E416","DOI":"10.1097\/00007632-200210010-00021","article-title":"Pulmonary embolism of polymethylmethacrylate after percutaneous vertebroplasty: a report of three cases.","volume":"27","author":"Jang","year":"2002"},{"key":"b9","series-title":"AJNR Am J Neuroradiol","first-page":"375","article-title":"Pulmonary embolism caused by acrylic cement: a rare complication of percutaneous vertebroplasty.","volume":"20","author":"Padovani","year":"1999"},{"key":"b10","series-title":"AJNR Am J Neuroradiol","first-page":"868","article-title":"Paradoxical cerebral arterial embolization of cement during intraoperative vertebroplasty: Case report.","volume":"23","author":"Scroop","year":"2002"},{"key":"b11","series-title":"Clin Orthop","first-page":"276","article-title":"The safety of cement fixation in the cervical spine. Studies of a rabbit model.","volume":"139","author":"Wang","year":"1979"}],"container-title":["Journal of Neurosurgery: Spine"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-spine\/99\/1\/article-p56.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-spine\/99\/1\/article-p56.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-spine\/99\/1\/article-p56.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T20:35:19Z","timestamp":1681590919000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-spine\/99\/1\/article-p56.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,7]]},"references-count":11,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.3171\/spi.2003.99.1.0056","relation":{},"ISSN":["1547-5654"],"issn-type":[{"value":"1547-5654","type":"print"}],"subject":[],"published":{"date-parts":[[2003,7]]}}}