{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T14:53:30Z","timestamp":1766588010745},"reference-count":41,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004,4]]},"abstract":"<jats:p content-type=\"fine-print\"><jats:italic>Object.<\/jats:italic> This 2-year experimental study was conducted to investigate the efficacy of a bioactive three-dimensional (3D) fabric disc for lumbar intervertebral disc replacement. The authors used a bioresorbable spinal fixation rod consisting of a forged composite of particulate unsintered hydroxyapatite\/poly-<jats:sc>l<\/jats:sc>-lactide acid (HA\/PLLA) for stability augmentation. The biomechanical and histological alterations as well as possible device-related loosening were examined at 2 years postoperatively.<\/jats:p>\n<jats:p content-type=\"fine-print\"><jats:italic>Methods.<\/jats:italic> Two lumbar intervertebral discs (L2\u20133 and L4\u20135) were replaced with the 3D fabric discs, which were augmented by two titanium screws and a spanning bioresorbable rod (HA\/PLLA). The segmental biomechanics and interface bone ingrowth were investigated at 6, 15, and 24 months postoperatively, and results were compared with the other two surgical groups (3D fabric disc alone; 3D fabric disc with additional anterior instrumentation stabilization). The 3D fabric disc and HA\/PLLA\u2014spinal segments demonstrated segmental mobility at 15 and 24 months; however, the range of motion (ROM) in flexion\u2014extension decreased to 49 and 40%, respectively, despite statistically equivalent preserved torsional ROM. Histologically there was excellent osseous fusion at the 3D fabric disc surface\u2014vertebral body interface. At 2 years posttreatment, no adverse tissue reaction nor aseptic loosening of the device was observed.<\/jats:p>\n<jats:p content-type=\"fine-print\"><jats:italic>Conclusions.<\/jats:italic> Intervertebral disc replacement with the 3D fabric disc was viable and when used in conjunction with the bioresorbable HA\/PLLA spinal augmentation. Further refinements of device design to create a stand-alone type are necessary to obviate the need for additional spinal stabilization.<\/jats:p>","DOI":"10.3171\/spi.2004.100.4.0337","type":"journal-article","created":{"date-parts":[[2009,5,7]],"date-time":"2009-05-07T16:00:06Z","timestamp":1241712006000},"page":"337-342","source":"Crossref","is-referenced-by-count":10,"title":["Two-year observation of artificial intervertebral disc replacement: results after supplemental ultra\u2014high strength bioresorbable spinal stabilization"],"prefix":"10.3171","volume":"100","author":[{"given":"Yoshihisa","family":"Kotani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuniyoshi","family":"Abumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuo","family":"Shikinami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiko","family":"Takahata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Kadoya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsuyoshi","family":"Kadosawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akio","family":"Minami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyoshi","family":"Kaneda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"J Neurosurg (Spine 4)","doi-asserted-by":"publisher","first-page":"468","DOI":"10.3171\/spi.2002.97.4.0468","article-title":"Applications of a resorbable interbody spacer in posterior lumbar interbody fusion.","volume":"97","author":"Alexander","year":"2002"},{"key":"b2","series-title":"J Neurosurg (Spine 4)","doi-asserted-by":"publisher","first-page":"440","DOI":"10.3171\/spi.2002.97.4.0440","article-title":"Feasibility of a resorbable anterior cervical graft containment plate.","volume":"97","author":"Ames","year":"2002"},{"key":"b3","series-title":"Biomaterials","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.1016\/0142-9612(96)84936-2","article-title":"The artificial disc: theory, design and materials.","volume":"17","author":"Bao","year":"1996"},{"key":"b4","series-title":"Clin Orthop","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1097\/00003086-200201000-00016","article-title":"Prosthetic disc replacement: the future?","volume":"394","author":"Bao","year":"2002"},{"key":"b5","series-title":"Int Orthop","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1007\/BF00268042","article-title":"Biomechanics of the SB Charite lumbar intervertebral disc endoprosthesis.","volume":"13","author":"Buttner-Janz","year":"1989"},{"key":"b6","series-title":"J Neurosurg (Spine 2)","doi-asserted-by":"publisher","first-page":"195","DOI":"10.3171\/spi.2003.98.2.0195","article-title":"Suitability of bioresorbable cages for anterior cervical fusion.","volume":"98","author":"Cahill","year":"2003"},{"key":"b7","series-title":"Spine","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1097\/00007632-199604150-00015","article-title":"Results of disc prosthesis after a minimum follow-up period of 2 years.","volume":"21","author":"Cinotti","year":"1996"},{"key":"b8","series-title":"Eur Spine J","doi-asserted-by":"publisher","first-page":"S115","DOI":"10.1007\/s00586-002-0481-z","article-title":"Total disc replacement arthroplasty using the AcroFlex lumbar disc: a non-human primate model.","volume":"11","author":"Cunningham","year":"2002"},{"key":"b9","series-title":"J Neurosurg (Spine 4)","doi-asserted-by":"publisher","first-page":"447","DOI":"10.3171\/spi.2002.97.4.0447","article-title":"Bioabsorbable anterior lumbar plate fixation in conjunction with cage-assisted anterior interbody fusion.","volume":"97","author":"DiAngelo","year":"2002"},{"key":"b10","series-title":"Spine","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1097\/00007632-199306150-00017","article-title":"Artificial disc replacement. 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