{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T16:59:50Z","timestamp":1700672390802},"reference-count":12,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["SPI"],"published-print":{"date-parts":[[2006,8]]},"abstract":"<jats:p>\u2713 The authors report the use of percutaneous transpedicular vertebroplasty performed using polymethylmethacrylate (PMMA) in two patients. These men (53 and 57 years old) had previously undergone open surgery and posterior instrumentation to treat myelomatous compression fractures. Both patients presented with acute back pain that manifested after minor activities. Kyphotic wedge fractures were diagnosed at T-11 in one case and at L-1 in the other. Both patients were treated at other hospitals with laminectomy and instrumented fusion; multiple myeloma was diagnosed after surgery. The patients experienced severe, recalcitrant, and progressive pain; on referral, they were found to have persistent kyphosis. Multiple myelomatous lesions of the spine were seen in one case and in the other the L-1 fracture represented the only site of disease. Percutaneous vertebroplasty was performed by injecting PMMA into the anterior third of the compressed vertebral body. Both patients experienced a 50% reduction in pain immediately after treatment; 3 months later both were walking and reported minimal back pain while undergoing treatment for multiple myeloma. Three years after surgery one patient reported no back pain and no progressive instability of the spine. Four years after surgery the other patient remains pain free, ambulatory, and with overall disease remission.<\/jats:p>\n<jats:p>Percutaneous vertebroplasty provided effective analgesia in these two patients with progressive back pain despite posterior stabilization. In both cases, the anterior column was effectively stabilized. A much larger operative intervention with its attendant risks of morbidity was avoided. In addition, subsequent aggressive medical treatment was well tolerated.<\/jats:p>","DOI":"10.3171\/spi.2006.5.2.168","type":"journal-article","created":{"date-parts":[[2008,1,24]],"date-time":"2008-01-24T12:21:36Z","timestamp":1201177296000},"page":"168-171","source":"Crossref","is-referenced-by-count":9,"title":["Percutaneous vertebroplasty of a myelomatous compression fracture in the presence of previous posterior instrumentation"],"prefix":"10.3171","volume":"5","author":[{"given":"Indro","family":"Chakrabarti","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery and Anesthesiology and Pain Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allen W.","family":"Burton","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and Anesthesiology and Pain Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ganesh","family":"Rao","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and Anesthesiology and Pain Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iman","family":"Feiz-Erfan","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and Anesthesiology and Pain Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roman","family":"Hlatky","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and Anesthesiology and Pain Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurence D.","family":"Rhines","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and Anesthesiology and Pain Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ehud","family":"Mendel","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and Anesthesiology and Pain Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-0050168","series-title":"Neurosurgery","first-page":"1105","article-title":"Percutaneous transpedicular polymethyl-methacrylate vertebroplasty for the treatment of spinal compression fractures","volume":"49","year":"2001"},{"key":"b2-0050168","series-title":"Spine","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1097\/00007632-200004150-00005","article-title":"Percutaneous vertebroplasty for pain relief and spinal stabilization","volume":"25","year":"2000"},{"key":"b3-0050168","series-title":"Semin Hematol","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1016\/S0037-1963(01)90020-4","article-title":"Myeloma bone disease","volume":"38","year":"2001"},{"key":"b4-0050168","series-title":"J Clin Oncol","doi-asserted-by":"publisher","first-page":"2382","DOI":"10.1200\/JCO.2002.09.097","article-title":"Kyphoplasty in the treatment of osteolytic vertebral compression fractures as a result of multiple myeloma","volume":"20","year":"2002"},{"issue":"(1 Suppl)","key":"b5-0050168","series-title":"J Neurosurg","first-page":"21","article-title":"Percutaneous vertebroplasty and kyphoplasty for painful vertebral body fractures in cancer patients","volume":"98","year":"2003"},{"key":"b6-0050168","series-title":"Chirurgie","first-page":"326","article-title":"[Percutaneous acrylic vertebroplasty as a treatment of vertebral angioma as well as painful and debilitating diseases.]","volume":"116","year":"1990"},{"key":"b7-0050168","series-title":"J Neurosurg Spine","doi-asserted-by":"publisher","first-page":"436","DOI":"10.3171\/spi.2005.2.4.0436","article-title":"Percutaneous vertebroplasty and kyphoplasty performed at a cancer center: refuting proposed contraindications","volume":"2","year":"2005"},{"issue":"(Suppl)","key":"b8-0050168","series-title":"Clin Orthop Relat Res","doi-asserted-by":"publisher","first-page":"S176","DOI":"10.1097\/01.blo.0000093841.72468.a8","article-title":"Vertebroplasty and kyphoplasty for osteolytic vertebral collapse","volume":"415","year":"2003"},{"key":"b9-0050168","series-title":"J Bone Joint Surg Am","doi-asserted-by":"publisher","first-page":"162","DOI":"10.2106\/00004623-199302000-00002","article-title":"Early failure of short-segment pedicle screw instrumentation for thoracolumbar fractures. A preliminary report","volume":"75","year":"1993"},{"key":"b10-0050168","series-title":"Clin Obstet Gynecol","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1097\/00003081-200209000-00038","article-title":"Multiple myeloma","volume":"45","year":"2002"},{"key":"b11-0050168","series-title":"J Bone Joint Surg Am","doi-asserted-by":"publisher","first-page":"2010","DOI":"10.2106\/00004623-200310000-00024","article-title":"Painful osteoporotic vertebral fracture. Pathogenesis, evaluation, and roles of vertebroplasty and kyphoplasty in its management","volume":"85","year":"2003"},{"key":"b12-0050168","series-title":"Osteoporos Int","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1007\/s001980170086","article-title":"Treatment of painful osteoporotic vertebral fractures with percutaneous vertebroplasty or kyphoplasty","volume":"12","year":"2001"}],"container-title":["Journal of Neurosurgery: Spine"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-spine\/5\/2\/article-p168.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-spine\/5\/2\/article-p168.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-spine\/5\/2\/article-p168.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,16]],"date-time":"2023-04-16T00:51:54Z","timestamp":1681606314000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-spine\/5\/2\/article-p168.xml"}},"subtitle":["Report of two cases"],"short-title":[],"issued":{"date-parts":[[2006,8]]},"references-count":12,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.3171\/spi.2006.5.2.168","relation":{},"ISSN":["1547-5654"],"issn-type":[{"value":"1547-5654","type":"print"}],"subject":[],"published":{"date-parts":[[2006,8]]}}}