{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T10:58:03Z","timestamp":1780052283824,"version":"3.53.1"},"reference-count":19,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["SPI"],"published-print":{"date-parts":[[2006,10]]},"abstract":"<jats:p>\u2713 Neuromas typically arise in the peripheral nervous system in response to traumatic injury at the site of partial or complete nerve transection as new axons from the proximal nerve stump sprout to reinnervate the distal segment. In rare cases neuromas have also been described as intramedullary spinal cord lesions. These lesions have been identified as incidental autopsy findings in association with prior trauma and cervical spondylosis, multiple sclerosis, spinal tumors, and syringomyelia.<\/jats:p>\n<jats:p>The authors report the case of a 50-year-old man who had been involved in a motor vehicle accident, during which his car was struck from behind as it was stationary at an intersection, more than 5 years before presentation. A workup for syncopal and presyncopal episodes involved magnetic resonance imaging that revealed a 1.1-cm lesion at the cervicomedullary junction (CMJ). The imaging features of the lesion raised the question of an ependymoma or subependymoma. The lesion was excised, and examination of the tissue demonstrated a neuroma with haphazardly arranged interlacing bundles of axons ensheathed by Schwann cells with interfascicular regions of reactive glial cells and Rosenthal fibers, consistent with those present after traumatic injury. This case may represent the first true traumatic intramedullary neuroma of the CMJ diagnosed in a living patient and treated surgically.<\/jats:p>","DOI":"10.3171\/spi.2006.5.4.362","type":"journal-article","created":{"date-parts":[[2008,1,24]],"date-time":"2008-01-24T13:12:52Z","timestamp":1201180372000},"page":"362-366","source":"Crossref","is-referenced-by-count":8,"title":["Intramedullary neuroma of the cervicomedullary junction"],"prefix":"10.3171","volume":"5","author":[{"given":"Sandro","family":"Santagata","sequence":"first","affiliation":[{"name":"Departments of Pathology, Neurosurgery, and Radiology, Brigham and Women\u2019s Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sagun","family":"Tuli","sequence":"additional","affiliation":[{"name":"Departments of Pathology, Neurosurgery, and Radiology, Brigham and Women\u2019s Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Don E.","family":"Wiese","sequence":"additional","affiliation":[{"name":"Departments of Pathology, Neurosurgery, and Radiology, Brigham and Women\u2019s Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur","family":"Day","sequence":"additional","affiliation":[{"name":"Departments of Pathology, Neurosurgery, and Radiology, Brigham and Women\u2019s Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umberto","family":"De Girolami","sequence":"additional","affiliation":[{"name":"Departments of Pathology, Neurosurgery, and Radiology, Brigham and Women\u2019s Hospital, Boston, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-0050362","series-title":"Surgical Pathology of the Nervous System and Its Coverings","year":"2002"},{"key":"b2-0050362","series-title":"Neuroscientist","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1177\/1073858404263511","article-title":"Intrinsic regenerative ability of mature CNS neurons","volume":"10","year":"2004"},{"issue":"1 Suppl","key":"b3-0050362","series-title":"J Neurosurg","first-page":"114","article-title":"Magnetic resonance imaging of intramedullary spinal cord schwannomas","volume":"99","year":"2003"},{"key":"b4-0050362","series-title":"Surg Neurol","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/S0090-3019(03)00537-8","article-title":"Spinal neurinomas: retrospective analysis and long-term outcome of 179 consecutively operated cases and review of the literature","volume":"61","year":"2004"},{"key":"b5-0050362","series-title":"J Neurol Neurosurg Psychiatry","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1136\/jnnp.28.2.121","article-title":"Aberrant peripheral nerve fibers in the medulla oblongata of man","volume":"28","year":"1965"},{"key":"b6-0050362","series-title":"Neurosurgery","first-page":"594","article-title":"Intramedullary neuroma of the cervical spinal cord: case report","volume":"39","year":"1996"},{"key":"b7-0050362","series-title":"Spinal Cord","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1038\/sj.sc.3100758","article-title":"Pathology of the spinal cord damaged by ossification of the posterior longitudinal ligament associated with spinal cord injury","volume":"37","year":"1999"},{"issue":"3 Suppl","key":"b8-0050362","series-title":"J Neurosurg","first-page":"393","article-title":"Traumatic neuroma of the anterior cervical nerve root with no subjective episode of trauma. 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