{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T14:28:47Z","timestamp":1747319327699},"reference-count":0,"publisher":"Journal of Nepal Medical Association (JNMA)","issue":"212","license":[{"start":{"date-parts":[[2018,8,31]],"date-time":"2018-08-31T00:00:00Z","timestamp":1535673600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Nepal Med Assoc"],"abstract":"<jats:p>Introduction: Preoperative diagnosis of intracranial space occupying lesion based solely on clinical and neuroimaging evaluation may not be sufficient to institute treatment plan without histopathological certainty. Frame based stereotactic biopsy is a technique of retrieving biopsy specimen to determine the histopathology. The aim of this study is to assess the efficacy and accuracy of frame based technique.&#x0D;\nMethods: This is a cross-sectional study conducted among 80 patients who underwent computed tomography guided frame based stereotactic biopsy during a period of 6 years. All operations were performed under local anesthesia. Histopathology reports were retrieved and accuracy of biopsy technique analyzed.&#x0D;\nResults: Out of 80 patients, 58 were male with male to female ratio of 2.6:1. Median age of patients were 50 years with range from 16 to 75 years. Most lesions were in deeper location lesions that was 49 (61.3%). Most common location was Parietal, 15 (18.8%) followed by Thalamic, 12 (15%). Mean size of lesion was 2.88\u00b10.71cms ranged from 2 to 5cms. Biopsy was accurate to retrieve target in 74 (92.5%) patients. Histopathology revealed glial tumor in 41 (51.2% ) of cases. Overall morbidity was observed in 3 (5.5%) patients. There is no procedure related mortality in this study during study period.&#x0D;\nConclusions: Frame based biopsy of intracranial space occupying lesion is safe and efficacious procedure with high diagnostic yield.<\/jats:p>","DOI":"10.31729\/jnma.3665","type":"journal-article","created":{"date-parts":[[2018,9,26]],"date-time":"2018-09-26T06:45:07Z","timestamp":1537944307000},"page":"749-753","source":"Crossref","is-referenced-by-count":3,"title":["Clinical Experience with Frame Based Stereotactic Biopsy for Intracranial Space Occupying Lesion"],"prefix":"10.31729","volume":"56","author":[{"given":"Suresh","family":"Bishokarma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shikher","family":"Shrestha","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Munu","family":"Napit","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dinesh Nath","family":"Gongal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"16919","published-online":{"date-parts":[[2018,8,31]]},"container-title":["Journal of Nepal Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/www.jnma.com.np\/jnma\/index.php\/jnma\/article\/download\/3665\/2774","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.jnma.com.np\/jnma\/index.php\/jnma\/article\/download\/3665\/2774","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,9,26]],"date-time":"2018-09-26T06:45:13Z","timestamp":1537944313000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jnma.com.np\/jnma\/index.php\/jnma\/article\/view\/3665"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,31]]},"references-count":0,"journal-issue":{"issue":"212","published-online":{"date-parts":[[2018,8,31]]}},"URL":"https:\/\/doi.org\/10.31729\/jnma.3665","relation":{},"ISSN":["1815-672X","0028-2715"],"issn-type":[{"value":"1815-672X","type":"electronic"},{"value":"0028-2715","type":"print"}],"subject":[],"published":{"date-parts":[[2018,8,31]]}}}