{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T00:59:06Z","timestamp":1791593946680,"version":"4.3.4"},"reference-count":0,"publisher":"Journal of Nepal Medical Association (JNMA)","issue":"213","license":[{"start":{"date-parts":[[2018,10,31]],"date-time":"2018-10-31T00:00:00Z","timestamp":1540944000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Nepal Med Assoc"],"abstract":"<jats:p>Epidermolysis bullosa is a rare inherited blistering disease with an incidence of 8-10 per million\r\nlive births. Dystrophic epidermolysis bullosa is a type of epidermolysis bullosa caused by mutation\r\nin type VII collagen, COL7A1. There are 14 subtypes of dystrophic epidermolysis bullosa and 400\r\nmutations of COL7A1. Electron microscopy is the gold standard diagnostic test but expensive.\r\nImmunofluorescence study is a suitable diagnostic alternative. Trauma prevention along with\r\nsupportive care is the mainstay of therapy. Squamous cell carcinoma develops at an early age in\r\nepidermolysis bullosa than other patients, particularly in recessive dystrophic epidermolysis bullosa\r\nsubtypes. Regular follow-up is imperative in detecting and preventing complications. Gene therapy,\r\ncell therapy and bone marrow transplantation are the emerging novel therapeutic innovations.\r\nPreventing possible skin and mucosal injury in patients requiring surgery should be worked on.\r\nHere, we present a case of dystrophic epidermolysis bullosa in a 26-year-old male.<\/jats:p>","DOI":"10.31729\/jnma.3791","type":"journal-article","created":{"date-parts":[[2018,11,7]],"date-time":"2018-11-07T18:02:23Z","timestamp":1541613743000},"page":"879-882","source":"Crossref","is-referenced-by-count":13,"title":["Dystrophic Epidermolysis Bullosa"],"prefix":"10.31729","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4075-3544","authenticated-orcid":false,"given":"Randhir Sagar","family":"Yadav","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7365-9864","authenticated-orcid":false,"given":"Amar","family":"Jayswal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7368-7884","authenticated-orcid":false,"given":"Shumneva","family":"Shrestha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay Kumar","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Upama","family":"Paudel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16919","published-online":{"date-parts":[[2018,10,31]]},"container-title":["Journal of Nepal Medical Association"],"original-title":[],"link":[{"URL":"http:\/\/www.jnma.com.np\/jnma\/index.php\/jnma\/article\/download\/3791\/2800","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.jnma.com.np\/jnma\/index.php\/jnma\/article\/download\/3791\/2800","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T20:20:16Z","timestamp":1621542016000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jnma.com.np\/jnma\/index.php\/jnma\/article\/view\/3791"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,31]]},"references-count":0,"journal-issue":{"issue":"213","published-online":{"date-parts":[[2018,10,31]]}},"URL":"https:\/\/doi.org\/10.31729\/jnma.3791","relation":{},"ISSN":["1815-672X","0028-2715"],"issn-type":[{"value":"1815-672X","type":"electronic"},{"value":"0028-2715","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10,31]]}}}