{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T17:42:40Z","timestamp":1648575760277},"reference-count":0,"publisher":"Journal of Nepal Medical Association (JNMA)","issue":"224","license":[{"start":{"date-parts":[[2020,4,30]],"date-time":"2020-04-30T00:00:00Z","timestamp":1588204800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Nepal Med Assoc"],"abstract":"<jats:p>Angina is a type of chest pain, experienced by patients with ischemic heart diseases. Cardiac autonomicmodulation as assessed by heart rate variability and baroreflex sensitivity is found reduced inischemic heart disease patients. Marked reduction in heart rate variability and baroreflex sensitivityin ischemic heart disease patients is found associated with sudden cardiac death. We report a caseof a 35-year-old man who presented with angina for the last few months. Thorough investigationsshowed no evidence of any cardiac or other systemic diseases. However, his cardiovascularautonomic modulation (as assessed by heart rate variability) and spontaneous baroreflex sensitivitywere markedly reduced. The patient had sudden death within 6 months of follow-up. Reportedly,no other specific abnormalities were found before death. This case report suggests that patientspresenting with typical chest pain as angina may have severe dysautonomia and risk of suddendeath even in the absence of cardiovascular or any other known end-organ diseases.<\/jats:p>","DOI":"10.31729\/jnma.4828","type":"journal-article","created":{"date-parts":[[2020,11,2]],"date-time":"2020-11-02T19:37:37Z","timestamp":1604345857000},"source":"Crossref","is-referenced-by-count":0,"title":["Severe Cardiac Dysautonomia and Sudden Death in a Patient Presenting with Anginal Symptoms in Absence of Cardiovascular and Other Diseases: A Case Report"],"prefix":"10.31729","volume":"58","author":[{"given":"Rita","family":"Khadka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajiv","family":"Narang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashok Kumar","family":"Jaryal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chetan","family":"Patel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kishore Kumar","family":"Deepak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"16919","published-online":{"date-parts":[[2020,4,30]]},"container-title":["Journal of Nepal Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/www.jnma.com.np\/jnma\/index.php\/jnma\/article\/download\/4828\/3144","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.jnma.com.np\/jnma\/index.php\/jnma\/article\/download\/4828\/3144","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,2]],"date-time":"2020-11-02T19:37:37Z","timestamp":1604345857000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jnma.com.np\/jnma\/index.php\/jnma\/article\/view\/4828"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,30]]},"references-count":0,"journal-issue":{"issue":"224","published-online":{"date-parts":[[2020,4,30]]}},"URL":"https:\/\/doi.org\/10.31729\/jnma.4828","relation":{},"ISSN":["1815-672X","0028-2715"],"issn-type":[{"value":"1815-672X","type":"electronic"},{"value":"0028-2715","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4,30]]}}}