{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T18:11:29Z","timestamp":1784657489410,"version":"3.55.0"},"reference-count":0,"publisher":"Journal of Nepal Medical Association (JNMA)","issue":"237","license":[{"start":{"date-parts":[[2021,5,17]],"date-time":"2021-05-17T00:00:00Z","timestamp":1621209600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Nepal Med Assoc"],"abstract":"<jats:p>Staphylococcus aureus is both a frequent commensal and a leading cause of endocarditis, bacteremia, osteomyelitis and skin and soft tissue infections and device-related infections. We performed this minireview to summarize the prevalence of Staphylococcus aureus among clinical samples and estimate the proportion of methicillin-resistant Staphylococcus aureus. The prevalence of Staphylococcus aureus among clinical isolates in Nepal is 34.5%. On average, the proportion of multi-drug resistance in Staphylococcus aureus is 57.1%. Methicillin-resistant Staphylococcus aureus accounts for a total of 41.7%. Inducible clindamycin resistance was detected in about 35% of the isolates. A regular antimicrobial resistance surveillance mechanism is necessary to mitigate the development of resistance among organisms and further spread of superbugs like methicillin-resistance Staphylococcus aureus.<\/jats:p>","DOI":"10.31729\/jnma.6251","type":"journal-article","created":{"date-parts":[[2021,5,18]],"date-time":"2021-05-18T10:33:56Z","timestamp":1621334036000},"source":"Crossref","is-referenced-by-count":9,"title":["Methicillin-resistant Staphylococcus aureus in Nepal"],"prefix":"10.31729","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0054-0715","authenticated-orcid":false,"given":"Lok Bahadur","family":"Shrestha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gopiram","family":"Syangtan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajaya","family":"Basnet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishna Prasad","family":"Acharya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arun Bahadur","family":"Chand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khilasa","family":"Pokhrel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16919","published-online":{"date-parts":[[2021,5,17]]},"container-title":["Journal of Nepal Medical Association"],"original-title":[],"deposited":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T19:59:04Z","timestamp":1621540744000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jnma.com.np\/jnma\/index.php\/jnma\/article\/view\/6251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,17]]},"references-count":0,"journal-issue":{"issue":"237","published-online":{"date-parts":[[2021,5,17]]}},"URL":"https:\/\/doi.org\/10.31729\/jnma.6251","relation":{},"ISSN":["1815-672X","0028-2715"],"issn-type":[{"value":"1815-672X","type":"electronic"},{"value":"0028-2715","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5,17]]}}}