{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T09:43:07Z","timestamp":1747215787370,"version":"3.40.5"},"reference-count":0,"publisher":"Journal of Nepal Medical Association (JNMA)","issue":"243","license":[{"start":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T00:00:00Z","timestamp":1636934400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Nepal Med Assoc"],"abstract":"<jats:p>Macrophage activation syndrome is a rare but a life threatening condition commonly associated with Systemic Juvenile Idiopathic Arthritis. Its clinical presentation includes fever, hepatosplenomegaly, hypertriglyceridemia, hypofibrinogenemia, hyperferritinemia and impaired liver enzymes. The symptoms are alarming yet non-specific and often lead to a delayed diagnosis. A 12 year male presented with a history of intermittent fever and was started on antibiotics but failed to respond after several days of hospital stay. After a series of investigations to rule out multiple diagnoses he was diagnosed as a case of Macrophage Activation Syndrome secondary to Systemic onset Juvenile Arthritis and was treated with steroids.<\/jats:p>","DOI":"10.31729\/jnma.7019","type":"journal-article","created":{"date-parts":[[2021,11,17]],"date-time":"2021-11-17T19:16:40Z","timestamp":1637176600000},"page":"1166-1169","source":"Crossref","is-referenced-by-count":0,"title":["Macrophage Activation Syndrome secondary to Systemic Juvenile Idiopathic Arthritis: A Case Report"],"prefix":"10.31729","volume":"59","author":[{"given":"Rishikesh","family":"Kafle","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6100-545X","authenticated-orcid":false,"given":"Anwesh","family":"Bhatta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1449-7105","authenticated-orcid":false,"given":"Sumit","family":"Gami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4146-7016","authenticated-orcid":false,"given":"Abhin","family":"Sapkota","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9032-2219","authenticated-orcid":false,"given":"Dipesh","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4301-7200","authenticated-orcid":false,"given":"Arabindra","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9062-0083","authenticated-orcid":false,"given":"Vijaya Kumar","family":"Chikanbanjar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"16919","published-online":{"date-parts":[[2021,11,15]]},"container-title":["Journal of Nepal Medical Association"],"original-title":[],"deposited":{"date-parts":[[2021,11,25]],"date-time":"2021-11-25T19:22:05Z","timestamp":1637868125000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jnma.com.np\/jnma\/index.php\/jnma\/article\/view\/7019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,15]]},"references-count":0,"journal-issue":{"issue":"243","published-online":{"date-parts":[[2021,11,15]]}},"URL":"https:\/\/doi.org\/10.31729\/jnma.7019","relation":{},"ISSN":["1815-672X","0028-2715"],"issn-type":[{"type":"electronic","value":"1815-672X"},{"type":"print","value":"0028-2715"}],"subject":[],"published":{"date-parts":[[2021,11,15]]}}}