{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:52:19Z","timestamp":1787068339335,"version":"build-2736575974"},"reference-count":0,"publisher":"Journal of Nepal Medical Association (JNMA)","issue":"260","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Nepal Med Assoc"],"abstract":"<jats:p>Introduction: Diabetes-thyroid relationship is said to be bidirectional. Insulin resistance and hyperinsulinemia in type 2 diabetes mellitus increase free thyroxine but decrease free tri-iodothyronine and thyroid-releasing hormone synthesis. Thyroid dysfunction may in turn impose an adverse effect on glucose metabolism in type 2 diabetes mellitus. Undetected thyroid dysfunction can worsen glycemic control and predispose type 2 diabetes mellitus patients to cardiovascular and other diabetes-related complications. Recognition and timely treatment of thyroid dysfunction in type 2 diabetes mellitus patients can delay diabetic complications. The aim of this study was to find out the prevalence of hypothyroidism among type 2 diabetic patients visiting the outpatient Department of Internal Medicine of a tertiary care centre.\nMethods: A descriptive cross-sectional study was conducted from 17 April 2021 to 5 September 2021 after obtaining ethical approval from the Institutional Review Committee (Reference number: 130120202). A total of 384 type 2 diabetic subjects were recruited for the study. Convenience sampling method was used. Point estimate and 95% CI were calculated.\nResults: Among 384 patients, the prevalence of hypothyroidism was found in 127 (33.07%) (28.36-37.78, 95% Confidence Interval). Among them, 56 (44.09%) were male and 71 (55.90%) were female. The mean age was 55.17\u00b17.53 years.\nConclusions: The prevalence of hypothyroidism was higher than in the other studies done in similar settings.<\/jats:p>","DOI":"10.31729\/jnma.8130","type":"journal-article","created":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T06:26:37Z","timestamp":1680503197000},"page":"325-328","source":"Crossref","is-referenced-by-count":4,"title":["Hypothyroidism among Type 2 Diabetic Patients Visiting Outpatient Department of Internal Medicine of a Tertiary Care Centre: A Descriptive Cross-sectional Study"],"prefix":"10.31729","volume":"61","author":[{"given":"Biju","family":"Shrestha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chandra Kala","family":"Rai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16919","published-online":{"date-parts":[[2023,4,1]]},"container-title":["Journal of Nepal Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/jnma.com.np\/jnma\/index.php\/jnma\/article\/download\/8130\/4558","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jnma.com.np\/jnma\/index.php\/jnma\/article\/download\/8130\/4558","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T06:26:38Z","timestamp":1680503198000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnma.com.np\/jnma\/index.php\/jnma\/article\/view\/8130"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,1]]},"references-count":0,"journal-issue":{"issue":"260","published-online":{"date-parts":[[2023,4,1]]}},"URL":"https:\/\/doi.org\/10.31729\/jnma.8130","relation":{},"ISSN":["1815-672X","0028-2715"],"issn-type":[{"value":"1815-672X","type":"electronic"},{"value":"0028-2715","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4,1]]}}}