{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T22:32:00Z","timestamp":1791412320488,"version":"4.3.3"},"reference-count":0,"publisher":"Journal of Nepal Medical Association (JNMA)","issue":"268","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Nepal Med Assoc"],"abstract":"<jats:p>Congenital adrenal hyperplasia occurs due to enzymatic defects in the adrenocortical steroidogenesis. 11\u03b2 hydroxylase deficiency is the second most common cause of congenital adrenal hyperplasia which presents with hypertension and features of androgen excess. Hypertension has also been found to cause end-organ damage in children with 11\u03b2 hydroxylase deficiency. We report a case of a 10-year-old male child with hypothyroidism under thyroid replacement therapy, presenting with features of severe hypertension and androgen excess, later on, diagnosed as congenital adrenal hyperplasia due to 11\u03b2 hydroxylase deficiency.<\/jats:p>","DOI":"10.31729\/jnma.8378","type":"journal-article","created":{"date-parts":[[2023,12,2]],"date-time":"2023-12-02T05:35:37Z","timestamp":1701495337000},"page":"956-957","source":"Crossref","is-referenced-by-count":1,"title":["11\u03b2 Hydroxylase Deficiency in a Child with Hypothyroidism: A Case Report"],"prefix":"10.31729","volume":"61","author":[{"given":"Bipesh Kumar","family":"Shah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richa","family":"Koirala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumit","family":"Dhamala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mukesh","family":"Bhatta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shekhar","family":"Khatiwada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"16919","published-online":{"date-parts":[[2023,12,1]]},"container-title":["Journal of Nepal Medical Association"],"original-title":[],"link":[{"URL":"http:\/\/www.jnma.com.np\/jnma\/index.php\/jnma\/article\/download\/8378\/4812","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.jnma.com.np\/jnma\/index.php\/jnma\/article\/download\/8378\/4812","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,4]],"date-time":"2023-12-04T05:35:56Z","timestamp":1701668156000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jnma.com.np\/jnma\/index.php\/jnma\/article\/view\/8378"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,1]]},"references-count":0,"journal-issue":{"issue":"268","published-online":{"date-parts":[[2023,12,1]]}},"URL":"https:\/\/doi.org\/10.31729\/jnma.8378","relation":{},"ISSN":["1815-672X","0028-2715"],"issn-type":[{"value":"1815-672X","type":"electronic"},{"value":"0028-2715","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12,1]]}}}