{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T17:44:12Z","timestamp":1773337452190,"version":"3.50.1"},"reference-count":0,"publisher":"Journal of Nepal Medical Association (JNMA)","issue":"269","license":[{"start":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T00:00:00Z","timestamp":1704153600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Nepal Med Assoc"],"abstract":"<jats:p>Sjogren\u2019s syndrome is a chronic multisystem autoimmune disease presenting a wide variety of clinical manifestations ranging from mild sicca symptoms to severe systemic symptoms involving pulmonary, renal, musculoskeletal, cutaneous, and haematological diseases. These symptomatic diversities can delay the correct diagnosis of Sjogren\u2019s Syndrome for a long time. Here, we report the case of a 59-year-old woman with fatigue and weakness in whom bicytopenia was documented. A thorough bicytopenia workup brought us to the final diagnosis of Sjogren\u2019s syndrome. Hydroxychloroquine was started which normalized the patient\u2019s blood parameters and clinical symptoms. The haematological alterations in Sjogren\u2019s syndrome are not pathognomonic. However, only bicytopenia can be the initial presentation of Sjogren\u2019s syndrome as in our patient. Therefore, inexplicable bicytopenia in a middle-aged female may alert the clinician about the possibility of Sjogren\u2019s syndrome. <\/jats:p>","DOI":"10.31729\/jnma.8406","type":"journal-article","created":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T05:44:21Z","timestamp":1704174261000},"page":"49-51","source":"Crossref","is-referenced-by-count":1,"title":["Primary Sjogren\u2019s Syndrome with Bicytopenia: A Case Report"],"prefix":"10.31729","volume":"62","author":[{"given":"Deepankar Raj","family":"Pathak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashish","family":"Kumar Chaurasiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rasish","family":"Subedi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prabin","family":"Khatri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pooja","family":"Shah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"16919","published-online":{"date-parts":[[2024,1,2]]},"container-title":["Journal of Nepal Medical Association"],"original-title":[],"link":[{"URL":"https:\/\/jnma.com.np\/jnma\/index.php\/jnma\/article\/download\/8406\/4829","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jnma.com.np\/jnma\/index.php\/jnma\/article\/download\/8406\/4829","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,13]],"date-time":"2024-01-13T05:49:34Z","timestamp":1705124974000},"score":1,"resource":{"primary":{"URL":"https:\/\/jnma.com.np\/jnma\/index.php\/jnma\/article\/view\/8406"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,2]]},"references-count":0,"journal-issue":{"issue":"269","published-online":{"date-parts":[[2024,1,1]]}},"URL":"https:\/\/doi.org\/10.31729\/jnma.8406","relation":{},"ISSN":["1815-672X","0028-2715"],"issn-type":[{"value":"1815-672X","type":"electronic"},{"value":"0028-2715","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1,2]]}}}